Lauren Payne specializes in providing support for a variety of evidence-based analyses involving food ingredients and additives, consumer products, and industrial chemicals. Ms. Payne conducts scoping and systematic literature reviews in PubMed, Embase, ToxPlanet, and other public and proprietary databases. In the systematic review process, Ms. Payne searches and selects studies for inclusion based on pre-defined criteria. She conducts preliminary reviews of titles/abstracts to determine potentially eligible studies for final review, and also participates as an evidence analyst, with roles that include extraction and devopment of evidence tables and landscape summaries.
Ms. Payne has supported a variety of scientific assessments, including worker and environmental safety assessments on microorgranisms. This process includes identification of toxicological data, as well as integration of regulatory considerations from both US and international agencies to ensure a comprehensive overview of the product. She has also conducted screening-level safety assessments for a variety of products used in the oil and gas industry.
Ms. Payne has assisted in the preparation and development of manuscripts by conceptualizing research questions, searching the literature, performing analyses, creating tables and figures, and writing to describe the study and communicate key findings.
Ms. Payne actively collaborates on projects through the Open Science Framework, an open-source repository that allows her to manage the research work flow, share, and register research projects. Additionally, she has experience registering protocols through Zenodo. She manages references using the bibliography software Zotero and Endnote. Using the systematic review software Distiller, Ms. Payne categorizes and extracts data on the study population, intervention or exposure, comparator, outcomes data, and study design. Ms. Payne has particular expertise in extraction of mechanistic data related to the key characteristics of carcinogenicity, as well as assessment of dose-response.
Ms. Payne’s past work has focused on the design and development of survey instruments and data collection forms, data management and data analysis, literature searches and reviews, and other research support related to a wide range of topics, including medical education, resiliency culture in the healthcare workforce, recruitment and retention of medical providers, substance use initiatives addressing the opioid crisis, health disparities in rural areas, disordered eating, pediatric oral health, psychiatric evaluation, and vaginal hysterectomies.