Dr. James has more than 35 years of experience in basic human and animal toxicological research and environmental consulting. He has worked with the departments of pharmacology, toxicology, and medicine at the University of Utah, Vanderbilt University, Georgia Institute of Technology, the University of Arkansas for Medical Science, the University of Florida, Florida State University, and the Medical College of Wisconsin. His basic and applied research has resulted in 75 scientific publications, and he is an editor of a toxicology textbook.
In addition to his academic career, Dr. James has served as a consulting environmental toxicologist since 1979. He has provided toxicological expertise, safety/risk assessment, and staff training to Fortune 500 companies, state environmental and public health departments, and federal entities such as the Department of Agriculture, USEPA, Department of Navy, Department of Justice, OSHA, and ACGIH.
As a toxicology consultant, Dr. James has authored hundreds of scientific evaluations in the areas of exposure-pathway and site-specific risk assessments and safety/risk evaluations for chemicals present in soil, water, air, various foods, and medicines; attached to indoor and outdoor surfaces; and present in consumer products or construction materials. The types of safety/risk assessments performed include complete chemical toxicological evaluations, technical comments on regulatory documents/approaches, hazard classifications (under Proposition 65, IARC, USEPA), derivation of toxicity constants (i.e., reference doses and slope factors), mechanistic evaluations, and historical state-of-the-art reviews. The chemicals of concern include but are not limited to heavy metals; radionuclides; industrially important chemicals and components of commercial products, petroleum products, organic solvents (BTEX, formaldehyde), chlorinated solvents, specific pesticides/fumigants, pharmaceuticals, consumer products and food chemicals (e.g., acrylamide, diacetyl), and environmentally persistent chemicals (e.g., brominated ethers, PFOA, PCBs, PCDD/Fs).
Dr. James’ experience in occupational and environmental exposures of consumer/commercial products, drugs, and industrial chemicals ultimately led to legal work both as a consultant and expert witness. He has worked on variety of legal issues, including site clean-up apportionment; in limine, Lone Pine, Kelly-Frye, and Daubert motions; issues of general and specific causation; and cases involving class certification, product safety, dose-reconstruction, liability, and toxic tort remedies such as medical surveillance.