Publications

Ciaccio PJ. Tew KD. 1996. Adaptive response to glutathione S-transferase inhibitors. Brit J Cancer 74:S93–S98

Ciaccio PJ, Shen H, Tew KD. 1996. Modulation of detoxification gene expression in HT29 colon cells by glutathione S-transferase inhibitors. In: Vermeulen NPE (ed), Proceedings of the International Workshop on Glutathione S-transferases. Taylor and Francis, pp. 213–226

Morgan AS, Ciaccio PJ, Tew KD, Kauvar LM. 1996. Isozyme specific GST inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chemother Pharmacol 37:363–370.

Ciaccio PJ, Jaiswal AK, Tew KD. 1994. Regulation of human dihydrodiol dehydrogenase by Michael acceptor xenobiotics. J Biol Chem 269(22):15558–15562

Ciaccio PJ, Stuart JE, Tew KD. 1993. Overproduction of a 37.5-kDa cytosolic protein structurally related to prostaglandin F synthase in ethacrynic acid-resistant human colon cells. Molec Pharmacol 43:845–853.

Ciaccio PJ. Tew KD. 1993. Glutathione S-transferases. In:  Teicher BA (ed), Drug Resistance in Oncology, Marcel Dekker, Inc., pp. 351–374.

Ranganathan S, Ciaccio PJ, Tew KD. 1993. Principles of drug modulation applied to glutathione S-transferases. In: Tew KD, Pickett CB, Mantle TJ, Mannervik B, Hayes JD (eds), Structure and Function of Glutathione Transferases. CRC Press, Boca Raton, FL, pp. 249–256

Tew KD, Ciaccio PJ, Ranganathan S. 1993. Glutathione S-transferases as determinants of cellular response to drugs. In: Miyazaki T, Takaku F, Sakurada K (eds), Mechanisms and New Approaches in Drug Resistance of Cancer Cells. Elsevier Science Publishers B.V., pp. 147–156.

Ciaccio PJ, Tew KD, LaCreta FP. 1991. The enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferase enzymes and inhibition by ethacrynic acid. Biochem Pharmacol 42(7):1504–1507

Ciaccio PJ, Graves PE, Bourque DP, Glinsmann-Gibson B, Halpert JR. 1991. cDNA and deduced amino acid sequences of a dog liver cytochrome P450 of the IIIA gene subfamily. Biochimica Biophysica Acta 1088:319–322

Graves PE, Elhag GA, Ciaccio PJ, Bourque DP, Halpert JR. 1990. cDNA and deduced amino acid sequences of a dog liver cytochrome P450IIB responsible for the metabolism of 2,2′,4,4′,5,5-hexachlorobiphenyl. Arch Biochem Biophys 281(1)106–115

Ciaccio PJ, Tew KD, LaCreta FP. 1990. The spontaneous and glutathione S-transferase-mediated reaction of chlorambucil with glutathione. Cancer Comm 2(8):279–286.

Ciaccio PJ, Halpert JR. 1989. Characterization of a phenobarbital-inducible dog liver cytochrome P450 structurally related to rat and human enzymes of the P450IIIA (steroid-inducible) gene subfamily. Arch Biochem Biophys 271(2):284–299.

Duignan DB, Sipes IG, Ciaccio PJ, Halpert JR. 1988. The metabolism of xenobiotics and endogenous compounds by the constitutive dog liver cytochrome P450 PBD-2. Arch Biochem Biophys 267(1):294–304.

Ciaccio PJ, Duignan DB, Halpert JR. 1987. Selective inactivation by chloramphenicol of the major phenobarbital-inducible isozyme of dog liver cytochromes P-450. Drug Metab Disposit 15(5):852–856.