2017 (53 POSTS)

Monticello TM, Jones TW, Dambach DM, Potter DM, Bolt MW, Liu M, Keller DA, Hart TK, Kadambi VJ. 2017. Current nonclinical testing paradigm enables safe entry to first-in-human clinical trials: The IQ consortium nonclinical to clinical translational database. Toxicol Appl Pharmacol 334:100–109, doi: 10.1016/j.taap.2017.09.006.

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Feifarek DJ*, Randolph EC, Milsk RY, Cavallin JE, Poole ST, Saari TW, et al. Reevaluating the significance of estrone as an environmental estrogen. Society of Environmental Toxicology and Chemistry Midwest Chapter Meeting, University of St. Thomas, Minneapolis, MN, 2017.

Villeneuve DL*, Blackwell BR, Cavallin JE, Cheng W, Feifarek DJ, Jensen KM, et al. Developing confidence in adverse outcome pathway-based toxicity predictions: Effects of the fungicide imazalil on fathead minnow reproduction. Society of Environmental Toxicology and Chemistry Europe Annual Meeting, Brussels, Belgium, 2017.

Jensen KM*, Ankley GT, Blackwell BR, Cavallin JE, Cheng W, Conolly R, Feifarek DJ, et al. The use of adverse outcome pathway-based toxicity predictions — A case study evaluating the effects of imazalil on fathead minnow reproduction. Society of Environmental Toxicology and Chemistry North America Annual Meeting, Minneapolis, MN, 2017.

Fay KA*, LaLone CA, Feifarek DJ, Doering JA, Cavallin JE, Villeneuve DL, Ankley GT. Addressing species diversity in biotransformation: Variability in expressed transcripts of Phase I and II hepatic enzymes among fishes. Society of Environmental Toxicology and Chemistry North America Annual Meeting, Minneapolis, MN, 2017.

Shappell NW, Feifarek DJ, Rearick DC, Bartell SE, Schoenfuss HL. 2017. Do environmental factors affect male fathead minnow (Pimephales promelas) response to estrone? Part 2. Temperature and food availability. Sci Tot Environ 611:32–43.

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Feifarek DJ, Shappell NW, Schoenfuss HL. 2017. Do environmental factors affect male fathead minnow (Pimephales promelas) response to estrone? Part 1. Dissolved oxygen and sodium chloride. Sci Tot Environ 610:1262–1270.

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Ankley GT, Feifarek DJ, Blackwell BR, Cavallin JE, Jensen KM, Kahl MD, Poole ST, Randolph EC, Saari TW, Villeneuve DL. 2017. Re-evaluating the significance of estrone as an environmental estrogen. Environ Sci Technol 51(10):4705–4713 (ACS Editor’s Choice Article; ES&T cover article).

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Thompson CM, Wolf, JC, McCoy A, Suh M, Proctor DM, Kirman CR, Haws LC, Harris MA. 2017. Comparison of toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens captan, folpet, and hexavalent chromium. Toxicol Pathol 45(8):1091–1101. DOI: 10.1177/019262331yy4324.

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2016 (55 POSTS)

Wirbisky SE, Weber GJ, Schlotman KE, Sepúlveda MS, Freeman JL. 2016. Embryonic atrazine exposure alters zebrafish and human miRNAs associated with angiogenesis, cancer, and neurodevelopment. Food Chem Toxicol 98:25–33.

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LaPlaca SB, Scott GI. Assessing potential endocrine disruption in largemouth bass from a PCB-contaminated reservoir in South Carolina. Poster presentation at the 37th annual meeting of the Society of Environmental Toxicology and Chemistry, North America Chapter, Orlando, FL, November 2016.

Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD, Chen C, et al. 2016. Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects. Crit Rev Toxicol 46:900–910, DOI: 10.1080/10408444.2016.1224807, open access online.

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Borghoff SJ, Ring C, Banton M, Leavens TL. 2016. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes.  J Appl Toxicol, DOI 10.1002/jat.3412

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Ulrich, K. Adversity and risk assessment of respiratory tract findings — A regulatory perspective. Presentation to the 31st Annual Meeting of the British Society of Toxicological Pathology (BSTP) — Association of Inhalation Toxicologists Joint Conference, Alderley Edge, Cheshire, UK, 2016.

Wirbisky SE, Sepúlveda MS, Weber GJ, Jannasch AS, Horzmann KA, Freeman JL. 2016. Embryonic atrazine exposure elicits alterations in genes associated with neuroendocrine function in adult male zebrafish. Toxicol Sci 153:149–164.

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Bi P, Yue F, Karki A, Castro B, Wirbisky SE, Wang C, … Kuang, S. 2016. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med 213(10):2019–2037.

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Bi P, Yue F, Sato Y, Wirbisky S, Liu W, Shan T, Wen Y, Zhou D, Freeman J, Kuang S. 2016. Stage-specific effects of notch activation during skeletal myogenesis. Elife 5:e17355.

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Schmitt G, Ridings J, De Schaepdrijver L, van Doesum-Wolters C, Cappon GD, Hartmann A. 2016. Nonclinical safety considerations for the development of pediatric-first drugs: An industry view. Therapeut Innov Regul Sci 50(5):632–638, DOI:10.1177/2168479016642813, online article.

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Mackay CE, Vivanco SN, Yeboah G, Vercellone J. 2016. Assessment of dermal hazard from acid burns with fire retardant garments in a full-size simulation of an engulfment flash fire. Burns 42(6):1350–1356.

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Williams K, Chesney AR. Proper study design and protocol for preclinical trials. Institute of Food Technologies Annual Meeting, Chicago, IL, July 19, 2016.