With the increasing prevalence of systematic reviews in toxicology and environmental research, a team of prominent scientists in the field convened a workshop to address the issue of ensuring scientific quality and integrity in this body of study. Dr. Daniele Wikoff, of ToxStrategies, was a member of this team, helping to apply the principles and methods of systematic review to the review process itself. The team proposed 58 editorial interventions, of which 26 were assessed as “potentially effective.” Of that group, five actions were highlighted as relatively easy for editors to implement in the effort to improve the quality of systematic reviews. The study was published in ALTEX, a journal focusing on alternatives to animal experimentation.