Publications

Kennedy SB, Heintz MM, Brown L, Fender CL, Hecker M, Hughes SA, Naile J, DeLeo P. Defining the domain of applicability: A case study to increase confidence in toxicogenomic tools for ecological risk assessment. Poster 1.03.P-Tu032, SETAC Europe 36^th Annual Meeting, Maastricht, The Netherlands, May 19, 2026.

Wigh A, Campos B, de Croze N, Roush K, Suzuki T, Brown L, Kennedy SB, Hecker M, et al. Chronic fish toxicity case studies toward a best practice guidance document. Poster 1.09P-Mo042, SETAC Europe 36^th Annual Meeting, Maastricht, The Netherlands, May 18, 2026.

Nordyke RJ. Panel Moderator: Can new approaches to estimating dynamic efficiency help to maintain both access and innovation in pharmaceutical markets? ISPOR 2026, Philadelphia, PA, May 19, 2026.

Nordyke RJ, Cyr P, Jensen I. Gene therapy development programs are both growing and evolving in the face of commercial headwinds. Poster Session 3/No. HPR71, ISPOR 2026, Philadelphia, PA, May 19, 2026.

Nordyke RJ, Jensen I, Hooda N, Miller B. Rising levels of innovation in expedited designations among FDA-approved drugs: 2012-2024. Poster Session 2/No. HPR63, ISPOR 2026, Philadelphia, PA, May 18, 2026.

Fitch S, Lozy F, Mitchell C, Patlewicz G, Wood A. Use of new approach methodologies in the safety assessment of dietary supplements—Parts one and two. Webinar series, Council for Responsible Nutrition (CRN), Washington, DC, May 2026.

Doepker C, Franzen A, Brorby G*, Wikoff D, Thompson C. From alerts to evidence: Advancing the use of in vivo genotoxicity dose-response data for complex mixtures. Poster/Abstract PA3, International Conference on the Science of Botanicals (ICSB), Oxford, MS, April 2026. (*poster only)

Wikoff D, Brown L. Development of an integrated human and environmental health safety assessment framework: Initial findings and progress from a consortium effort. Abstract 1050, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Wikoff D, Fitch S, Eichenbaum G, Ejaz S, Klaren W, Southall M. Need for fit-for-purpose approaches that integrate dose, mechanism, and context of use with key characteristics when evaluating the carcinogenic potential of widely used therapeutics: A case study of acetaminophen. Abstract 4005, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Vincent M, Wheeler M, Schaefer H, Rhoden J, Fitch S, Wikoff D. Quantitative bias assessment to facilitate assessment of (un)certainty in observational data evaluating acetaminophen use and liver cancer. Abstract 4279, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Shobair M, Allen D, Ballone I, Brull M, Burbank M, Choksi N, Fitch S, Irizar A, et al. A machine-learning approach for the development of a knowledgebase to identify systemic toxicity mechanistic targets and evaluate biological space coverage. Abstract 5161, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Proctor DM, Verwiel AH, Covington TR, Thompson CM. Acute (24-hour) nickel inhalation reference concentration for use in air toxics risk assessment. Abstract 3997, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Price SA, Bare JL, Verwiel AH, Proctor DM. Novel application of the EPA All Ages Lead Model (AALM) to determine an acute (24-hour) inhalation threshold for lead protective of neurotoxicity in children. Abstract 4604, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Patlewicz G, Mihalchik A, Thompson CM, East A, Borghoff S. Investigating the feasibility of deriving a new environmentally relevant Thresholds of Toxicological Concern (TTCs) from estimated human equivalent benchmark dose (eBMD_HED) values. Abstract 4013, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Lea I, Rivera B, Rogers S, Borghoff SJ. Assessment of the carcinogenic potential of automotive gasoline in humans based on mechanistic evidence. Abstract 5206, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Abstract 3653, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Klaren WD, East A, Wheeler M, Vincent M, Wikoff DS, Covington T. Probabilistic estimation of daily total nitrosamine exposures generated from drinking water and dietary nitrate and nitrate sources. Abstract 3982, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Killius A, Covell LT. Characterization of PFAS in Vermont public water systems. Abstract 3892, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Henderson RG, Hinerman J, Franzen A, Nguyen H, Wong A. Development of supplemental intake limits for nutrients. Abstract 3664, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Greene N. The role of AI in advancing drug discovery. Abstract 1055, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.