Rager JE, Suh M , Chappell G, Thompson CM , Proctor DM . 2019. Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis. Toxicol Lett 305:40-50.
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Publication: Manuscripts
/ Topics: Cr(VI) MOA Study , Hexavalent Chromium
Wikoff DS , Rager JE, Chappell GA, Fitch S , Haws L , Borghoff SJ . 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335.
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Publication: Manuscripts
/ Topics: Systematic Review
Wikoff D . Problem formulation: Lessons and tools from practical applications involving systematic review of mechanistic data. Presented at Strategies and Tools for Conducting Systematic Reviews of Mechanistic Data to Support Chemical Assessments, National Academies of Sciences, Engineering, and Medicine. Washington, D.C., December 2018.
Publication: Abstracts and Presentations
/ Topics: Systematic Review
Urban J , Wikoff D , Haws L , Fitch S , Ring C, Thompson C , Suh M . 2018. Systematic review protocol: Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count. Zenodo. http://doi.org/10.5281/zenodo.1636357 .
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Publication: Protocol Registrations
/ Topics: Systematic Review
Lewis RC, Meeker JD, Basu N, Gauthier AM , Cantoral A, Mercado-García A, Watkins DJ. 2018. Urinary metal concentrations among mothers and children in a Mexico City birth cohort study. Int J Hyg Environ Health 221(4):609–615.
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Publication: Manuscripts
/ Topics: Epidemiology
Kimzey AL , Piche M-S, Wood M , Weir AB, Lansita J. 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3rd Ed. Vol 11:399–427 .
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Publication: Book Chapters
/ Topics: Toxicology
Brorby G , Ring C, Loko F, Harris MA . Characterization of hexavalent chromium and total chromium in drinking water monitoring data. Poster MP 117. Society of Environmental Toxicology and Chemistry (SETAC) North America 39th Annual Meeting, Sacramento, CA, November 4–8, 2018.
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Publication: Abstracts and Presentations
/ Topics: Hexavalent Chromium
Tsaioun K, Dirven H, Beck Færden K, Wikoff D , Ram R, Kleinstreuer N, McCormack A, Wright R, Vist GE, Fitch S . 2018. Systematic reviews of the hepatotoxic effects of specified compounds/drugs as observed in humans and experimental animals (rats, mice, dogs and non-human primates). PROSPERO CRD42018112353 .
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Publication: Protocol Registrations
/ Topics: Systematic Review
Grimm FA, Blanchette A , House JS, Ferguson K, Hsieh N-H, Dalaijamts C, Wright AA, Anson B, Wright FA, Chiu WA, Rusyn I. 2018. A human population-based organotypic in vitro model for cardiotoxicity screening. ALTEX 35(4):441–452, Epub 2018/07/08 , doi: 10.14573/altex.1805301. PMID: 29999168.
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Publication: Manuscripts
/ Topics: Toxicology
LaPlaca SB . Toxicological effects of tire wear particles on mummichogs and fathead minnows. Poster presentation at annual meeting of the Society of Environmental Toxicology and Chemistry, North America Chapter, Sacramento, CA, November 2018.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Suh M , Wikoff D , Harvey S , Mittal L , Lipworth L, Goodman M, Goodmanson A, Ring C, Rohr A, Proctor D . Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.
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Publication: Abstracts and Presentations
/ Topics: Hexavalent Chromium , Systematic Review
Borghoff SJ, Fitch S , Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99:168–181.
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Publication: Manuscripts
/ Topics: PFAS , Toxicology
Ring CL, Suh M , Casteel S, Dunsmore M, Verwiel A , Proctor D . Relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.
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Publication: Abstracts and Presentations
/ Topics: Metals , Toxicology
Harrill AH, Borghoff S , Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ. 2018. NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies. National Toxicology Program Research Report 6, Research Triangle Park, NC.
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Publication: Manuscripts
/ Topics: Toxicology
Chowdhary P, Vivanco SN , Kelly C, Leiga A. What’s in your laundry detergent? An evaluation of common surfactants found in laundry detergents and their PBT characteristics. Presentation to Society of Environmental Toxicology and Chemistry, November 2018.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Vivanco SN , Chowdhary P, Kelly C. Evaluating Prop65 exposure to ethylene oxide and 1,4-dioxane in personal care products. Presentation to Society of Environmental Toxicology and Chemistry, November 2018.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Chesney AR , O’Brien KM, Jordan H, Bakko A, Drey H, Ealy D, Wheiland T, Osinski M. Plethysmography versus blood-gas parameters: Overlap and considerations in nonclinical safety assessment studies. Society of Toxicology, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Casey WM, Chang X, Allen DG, Ceger PC, Choksi NY , Hsieh JH, et al. 2018. Evaluation and optimization of pharmacokinetic models for in vitro to in vivo extrapolation of estrogenic activity for environmental chemicals. Environ Health Perspect 126:97001, DOI: 10.1289/EHP1655
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Publication: Manuscripts
/ Topics: Toxicology
Wikoff DS, Thompson C , Rager J, Chappell G, Fitch S, Doepker C . 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120:709-723.
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Publication: Manuscripts
/ Topics: Toxicology
McMillan DA . Large scale botanical and phytochemical data to assist in rapid analysis for safety assessment. 18th Annual Oxford International Conference on the Science of Botanicals, Oxford, MS, April 2018.