Publications

Wikoff D, Brown L. Development of an integrated human and environmental health safety assessment framework: Initial findings and progress from a consortium effort. Abstract 1050, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Wikoff D, Fitch S, Eichenbaum G, Ejaz S, Klaren W, Southall M. Need for fit-for-purpose approaches that integrate dose, mechanism, and context of use with key characteristics when evaluating the carcinogenic potential of widely used therapeutics: A case study of acetaminophen. Abstract 4005, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Vincent M, Wheeler M, Schaefer H, Rhoden J,  Fitch S, Wikoff D. Quantitative bias assessment to facilitate assessment of (un)certainty in observational data evaluating acetaminophen use and liver cancer. Abstract 4279, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Shobair M, Allen D, Ballone I, Brull M, Burbank M, Choksi N, Fitch S, Irizar A, et al. A machine-learning approach for the development of a knowledgebase to identify systemic toxicity mechanistic targets and evaluate biological space coverage. Abstract 5161, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Proctor DM, Verwiel AH, Covington TR, Thompson CM. Acute (24-hour) nickel inhalation reference concentration for use in air toxics risk assessment. Abstract 3997, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Price SA, Bare JL, Verwiel AH, Proctor DM. Novel application of the EPA All Ages Lead Model (AALM) to determine an acute (24-hour) inhalation threshold for lead protective of neurotoxicity in children. Abstract 4604, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Patlewicz G, Mihalchik A, Thompson CM, East A, Borghoff S. Investigating the feasibility of deriving a new environmentally relevant Thresholds of Toxicological Concern (TTCs) from estimated human equivalent benchmark dose (eBMD_HED) values. Abstract 4013, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Lea I, Rivera B, Rogers S, Borghoff SJ. Assessment of the carcinogenic potential of automotive gasoline in humans based on mechanistic evidence. Abstract 5206, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Abstract 3653, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Klaren WD, East A, Wheeler M, Vincent M, Wikoff DS, Covington T. Probabilistic estimation of daily total nitrosamine exposures generated from drinking water and dietary nitrate and nitrate sources. Abstract 3982, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Killius A, Covell LT. Characterization of PFAS in Vermont public water systems. Abstract 3892, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Henderson RG, Hinerman J, Franzen A, Nguyen H, Wong A. Development of supplemental intake limits for nutrients. Abstract 3664, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Greene N. The role of AI in advancing drug discovery. Abstract 1055, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Buerger AN, Heintz MM, Haws LC, Nyambego H, Palermo CM, Thompson CM. Mode of action and human relevance assessment for diisononyl phthalate (DINP)-induced liver tumors in rodents. Abstract 3324, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Buerger AN, Lea IA, Vincent MJ,…, Choksi NY, Britt J, Fitch S, Rogers S, Schaefer H, Haws L,…, Wikoff D, Borghoff SJ. Systematic evaluation of the carcinogenic potential of di-isononyl phthalate in humans. Abstract 3314, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Beggs AH, Haselkorn T, Solomon F, Rumantir R, Bylsma LC, Vue S, Mitchell M, Kelsh M, Sacks NC, Graham RJ. Epidemiology of x-linked myotubular myopathy (XLMTM) in the United States using a machine learning model. Abstract/Poster 106S, Muscular Dystrophy Association (MDA) Clinical and Scientific Conference, Orlando, FL, March 2026.

Wheeler M, Wikoff D, Vincent M. Annealed Bayesian bias assessment in epidemiological studies. Session M2-H, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Verwiel A, Rish W. Importance of integrating cumulative chemical exposures into cumulative impact assessment for vulnerable communities. Session T1-A, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Hoffman S, Wikoff D, Brown L, Wheeler M. Advancing quantitative uncertainty assessment in next generation risk assessment. Session T2-A, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Broome C, Hausrath D, Jaworski J, Fernandez S, Edwards T,…, Bylsma L, Kelsh M,.., Mitchell M. Survival outcomes of patients with secondary hemophagocytic lymphohistiocytosis at two academic medical centers in the United States. Poster 905, Blood 146(Sup 1):6243; doi: 10.1182/blood-2025-6243. 67^th American Society of Hematology (ASH) Annual Meeting and Exposition, Orlando, FL, November 2025.