Publication Topic

Mihalchik AL, Roberts A, LaCombe J, Lloyd M, Doepker C, Eapen A. 2026. Evaluation of the safety and potential genotoxicity of a high-purity mogroside ingredient containing siamenoside I produced from a modified strain of Yarrowia lipolytica. Toxicol Rep 17(Dec):102297; doi: 10.1016/j.toxrep.2026.102297. PMID: 42388455.

Fitch S, Lozy F, Mitchell C, Patlewicz G, Wood A. Use of new approach methodologies in the safety assessment of dietary supplements—Parts one and two. Webinar series, Council for Responsible Nutrition (CRN), Washington, DC, May 2026.

Doepker C, Franzen A, Brorby G, Brown L, Choksi N, East A, Wikoff D. 2026. Smoke flavoring—A case study demonstrating the value of using benefit-risk analysis for foods (BRAFO) to provide transparency for risk management decisions. Regul Toxicol Pharmacol 167(May):106033; doi: 10.1016/j.yrtph.2026.106033. PMID: 41577161.

Summan M, Doepker CL, Brorby GP. 2026. Safety evaluation of an aqueous root and leaf extract of Ashwagandha (Withania somnifera). Phytother Res; doi: 10.1002/ptr.70314. Online ahead of print April 15. PMID: 41987003.

Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Abstract 3653, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Klaren WD, East A, Wheeler M, Vincent M, Wikoff DS, Covington T. Probabilistic estimation of daily total nitrosamine exposures generated from drinking water and dietary nitrate and nitrate sources. Abstract 3982, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Greenfield MR, Frankenfeld C, Pendala A, Ozmeral A, Pendala V, Baustian N, Seng EK, Pavlovic JM, et al. 2026. Variations of dietary intake across migraine phases in adults with episodic migraine: A prospective observational pilot study. Curr Dev Nutr 10(4):107668; doi: 10.1016/j.cdnut.2026.107668. PMID: 41970508.

Choksi N, McMillan D, Schmitt D, Doepker C, Henderson RG. 2026. Demonstration of safety for rice bran wax and sunflower wax based on bridging to other naturally derived waxes used in food. Regul Toxicol Pharmacol 165(Feb):105990; doi: 10.1016/j.yrtph.2025.105990. PMID: 41248699.

 Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS. 2025. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Curr Res Toxicol 9(Sep):100256; doi: 10.1016/j.crtox.2025.100256. PMID: 41030520.

Brorby G, Franzen A, Thompson C, Wikoff D, Doepker C. 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490. PMID: 40320068.

Crincoli CM, van de Ligt JLG, Eapen AK. Pavel AT, Hanlon PR, Almond-Abbate K, Haugabrooks E,… Henderson RG. 2025. A tool to support food substance safety evaluations in the United States. Regul Toxicol Pharmacol 161(Sept):105838; doi: 10.1016/j.yrtph.2025.105838. PMID: 40324559.

Price S, Chen K, Finley B. Estimating infant blood levels from baby food consumption: A biokinetic model analysis. Abstract 4080, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Massarsky A, Buerger AN, O’Neill HC, Gaffner J, Mucs D, Baskerville-Abraham I, Maier A. Derivation of Maximum Acceptable Group Levels (MAGLs) for ionones and related compounds. Abstract 4764, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.

Wikoff D. Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.

Wikoff D. Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.

Rana Z, Frankenfeld CL, Kennedy E, Bertoldi J, de Jonge E, Cheskin L. 2025. Food sources of energy and nutrients among US college students: The Health Starts Here cohort study. J Am Coll Health 73(1):301-310; doi: 10.1080/07448481.2023.2220397. PMID: 37290009.

Bates CA, Vincent MJ, Buerger AN, Santamaria AB, Maier A, Jack M. 2024. Investigating the relationship between β-carotene intake from diet and supplements, smoking, and lung cancer risk. Food Chem Toxicol 194:115104; doi: 10.1016/j.fct.2024.115104. PMID: 39522798.

Mattes RD, Rivera BN, Rutigliani GR, Rogers S, Mendoza ID, Wang L, Beckemeier K, Wikoff D. 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723.

Movva N, Mitchell M, Bylsma L, Suh M, Frankenfeld C. 2024. Systematic literature review of bioavailability of nutrients from whole dairy products versus plant-based alternative dairy products. PROSPERO 2024:CRD42024591715. Available from: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024591715.

Doepker C, Rabert C, Heard P, Dubnicka T, Choksi N, Eapen A. 2024. An investigation of the genotoxic potential of a well-characterized yerba mate extract. Toxicol Rep 12(June):477–484; doi: 10.1016/j.toxrep.2024.04.007. PMID: 38708314.