Publications

Borghoff SJ, Heintz MM, Rivera BN, Haws L, Thompson C. 2025. Evaluation of an anti-thyroid mode of action for thyroid follicular cell adenomas in female mice exposed to tertiary butyl alcohol. Regul Toxicol Pharmacol 163(Dec):105936; doi: 10.1016/j.yrtph.2025.105936. PMID: 40914479.

Fitch S, Rogers J, Marty S, Norman J, Schneider S, Rushton E, Wikoff D, Ellis-Hutchings R. 2025. Systematic review of potential developmental and reproductive toxicity of microplastics. Toxicol Sci 207(2):289-305; doi: 10.1093/toxsci/kfaf108. PMID: 40794567.

Hampton LMT, Wyler DB, Almroth BC, Coffin S, Cowger W, Doyle D,… Bare JL,… Kennedy SB, et al. 2025. The toxicity of Microplastics Explorer (ToMEx) 2.0. Microplast Nanoplast 5(1):38; doi: 10.1186/s43591-025-00145-6. PMID: 41019257.

Rish W, Racz L, Hale A. 2025. Public radiation dose from conventional gas-well produced water used as a pavement Deicer. J Waste Manag Assoc;  doi: 10.1080/10962247.2025.2565287. Online ahead of print Sept. 23, 2025. PMID: 40985694.

Wambaugh JF, Sipes NS, Padilla Mercado G, Arnot JA, Bertato L, Brown TN, Chirico N,…, Patlewicz G, et al. 2026. Collaborative evaluation of in silico predictions for high throughput toxicokinetics. Toxicol In Vitro 110(Jan):106150; doi: 10.1016/j.tiv.2025.106150. ePub September 20, 2025. PMID: 40983213.

 Klaren WD, Rivera BN, Sheppard AM, Franke K, Wikoff DS. 2025. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Curr Res Toxicol 9(Sep):100256; doi: 10.1016/j.crtox.2025.100256. PMID: 41030520.

Patlewicz G, Charest N, Ross A, Bledsoe HC, Vidal J, Faramarzi S, Hagan B, Shah I. 2025. Building a compendium of expert driven read-across cases to facilitate an analysis of the contribution that different similarity contexts play in read-across performance. Comput Toxicol 35(Sept):100366; doi: 10.1016/j.comtox.2025.100366.

Nyffeler J, Harris FR, Willis C, Byrd G, Blackwell B, Escher BI, Kasparek A, Nichols J,…, Patlewicz G, et al. 2025. A combination of high-throughput in vitro and in silico new approach methods (NAMs) for ecotoxicology hazard assessment for fish. Environ Toxicol Chem 44(9):2599-2621; doi: 10.1093/etojnl/vgae083. PMID: 39937625.

Nordyke RJ, Patterson JA, Motyka J, March B, Kirson NY, Long G. 2025. The impact of the Inflation Reduction Act’s drug price negotiation program on incentives for clinical development of new drugs. Value Health; doi: 10.1016/j.jval.2025.08.011. Online ahead of print Sept. 1, 2025. PMID: 40902797.

Karamertzanis PG, Rasenberg M, Shah I, Patlewicz G. 2025. Modelling in vitro mutagenicity using multi-task deep learning and REACH data. Chem Res Toxicol 38(8):1382-1407; doi: 19.1021/acs.chemrestox.5c00152. PMID: 40680271.

Muller K, Unice K, Panko J, Ferrari BJD, Breider F, Wagner S. 2025. Risk assessment of tire wear in the environment—A literature review. Environ Sci Process Impacts 27(8):2212-2232; doi: 10.1039/d5em00088b. PMID: 40569214.

Reynolds JI, Johnson BP. 2025. AOP 460: Antagonism of Smoothened receptor leads to orofacial clefting. ALTEX; doi: 10.14573/altex.2407121. Advance online publication August 11, 2025.

Proctor D, Jiang X, Reichert H, Thompson C. 2025. Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium. Toxicol Sci kfaf112; doi: 10.1093/toxsci/kfaf112. Online ahead of print August 8, 2025. PMID: 40795394.

Moyer HL, Vergara L, Stephan C, Sakolish C, Lin HC, Chiu WA, Villenave R, Hewitt P, et al. 2025. Human small intestinal tissue models to assess barrier permeability: Comparative analysis of caco-2 cells, jejunal and duodenal enteroid-derived cells, and EpiIntestinal^TM tissues in membrane-based cultures with and without flow. Bioengineering (Basel). 12(8):809; doi: 10.3390/bioengineering12080809. PMID: 40868322; PMCID: PMC12384003.

Clouser MC, Suh M, Movva N, Hildebrand JS, Pastula ST, Schoehl M, Hindoyan A, Balasubramanian A, et al. 2025. A systematic literature review of MTAP deletions in solid and hematologic cancers. Cancer Treat Res Comm 44:100966; doi: 10.1016/j.ctarc.2025.100966. PMID: 40729867.

Patlewicz G, Judson, Paul Friedman K, Wetmore BA, DeVito MJ, Harrill JA, Carstens KE, Houck KA, et al. 2025. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs). J Toxicol Environ Health B online ahead of print July 6; doi: 10.1080/10937404.2025.2521615. PMID: 40619890.

Kenyon EM, DeVito MJ, Patlewicz G, Adams LD, Thomas RS, Ambroso JL, Yang X, Blake JC, et al. 2025. Subchronic toxicity of four per- and polyfluoroalkyl substances by oral exposure in Sprague Dawley rats. Toxics 13(7):524; doi: 10.3390/toxics13070524. PMID: 40710969.

Gauthier A, Behymer W, Bare J, Kramer M, Barranco WT, Longtin JP, Borghoff S, Jaques A. 2025. Measurement of vinyl acetate monomer in consumer products and modeled estimates of consumer exposure. J Exp Sci Environ Epidemiol; doi: 10.1038/s41370-025-00786-y. Online ahead of print June 18, 2025. PMID: 40533479.

Leary A, Shah I, Patlewicz G. 2025. An exploration of the use of hybrid fingerprints in Generalized Read-Across and their impact on predictive performance for selected in vivo toxicity outcomes. Comput Toxicol 34(June):100349; doi: 10.1016/j.comtox.2025.100349.

Hagan B, Shah I, Patlewicz G. 2025. Can graph similarity metrics be helpful for analogue identification as part of a read-across approach? Comput Toxicol 34(June):100353; doi: 10.1016/j.comtox.2025.100353.