2025 (60 POSTS)
Choksi N , McMillan D, Schmitt D , Doepker C , Henderson RG . 2025. Demonstration of safety for rice bran wax and sunflower wax based on bridging to other naturally derived waxes used in food. Regul Toxicol Pharmacol 105990; doi: 10.1016/j.yrtph.2025.105990 . PMID: 41248699. Advance online publication November 15, 2025.
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Topics: food safety , Food science , safety assessment
Garcia MM, Pearce JL, Jacobellis MA , Baldwin WS, Hunt KJ, Bain LJ. 2025. Mixtures of p ,p ′-DDE, PCB153, BDE47, and PFOS alter adipocytic differentiation of 3T3-L1 cells. Toxics 13(11):975 ; doi: 10.3390/toxics13110975 .
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Topics: PCBs , PFAS
Gauthier A, Behymer W, Bare J, Kramer M , Barranco WT, Longtin JP, Borghoff S , Jaques A. 2025. Measurement of vinyl acetate monomer in consumer products and modeled estimates of consumer exposure. J Exp Sci Environ Epidemiol 35(6):933-942; doi: 10.1038/s41370-025-00786-y . PMID: 40533479.
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Topics: consumer products , Exposure Assessment
Proctor D , Jiang X , Reichert H , Thompson C . 2025. Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium. Toxicol Sci 208(1):42-47; doi: 10.1093/toxsci/kfaf112 . PMID: 40795394.
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Topics: Cancer , chromium , Exposure Assessment , risk assessment
Allen BC, Vincent MJ , Lipworth L, Panko JM, Suh M, Jiang X , Mumma MT, Proctor DM . 2025. Lung cancer risk assessment associated with exposure to hexavalent chromium: Results of pooled analysis of three cohorts. J Occup Environ Hyg 22(10):821-835; doi: 10.1080/15459624.2025.2502491 . PMID: 40435461.
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Topics: Cancer , chromium , Exposure Assessment , risk assessment
Preib MT, Emden MR, Sacks NC , Mitrani-Gold FS, Ju S, Kawano Y, Kawamatsu S, Joshi AV. 2025. Prevalence and economic evaluation of acute uncomplicated cystitis in women from Japan: A retrospective cohort study. JAC Antimicrob Resist 7(5):dlaf178; doi: 10.1093/jacamr/dlaf178 . PMID: 41113066.
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Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Borghoff SJ, Heintz MM, Rivera BN, Haws L, Thompson C . 2025. Evaluation of an anti-thyroid mode of action for thyroid follicular cell adenomas in female mice exposed to tertiary butyl alcohol. Regul Toxicol Pharmacol 163(Dec):105936; doi: 10.1016/j.yrtph.2025.105936 . PMID: 40914479.
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Topics: mode of action , water
Fitch S , Rogers J , Marty S, Norman J, Schneider S, Rushton E, Wikoff D , Ellis-Hutchings R. 2025. Systematic review of potential developmental and reproductive toxicity of microplastics. Toxicol Sci 207(2):289-305; doi: 10.1093/toxsci/kfaf108 . PMID: 40794567.
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Topics: microplastics , Systematic Review
Seal S, Trapotsi M, Subramanian V, Spjuth O, Greene N , Bender A. 2025. PKSmart: An open-source computational model to predict in vivo pharmacokinetics of small molecules. J Cheminform 17(1):147; doi: 10.1186/s13321-025-01066-5 .
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Topics: computational toxicology , pharmacokinetics
Hampton LMT, Wyler DB, Almroth BC, Coffin S, Cowger W, Doyle D,… Bare JL ,… Kennedy SB , et al. 2025. The toxicity of Microplastics Explorer (ToMEx) 2.0. Microplast Nanoplast 5(1):38; doi: 10.1186/s43591-025-00145-6 . PMID: 41019257.
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Topics: microplastics
Rish W , Racz L , Hale A . 2025. Public radiation dose from conventional gas-well produced water used as a pavement Deicer. J Waste Manag Assoc; doi: 10.1080/10962247.2025.2565287 . Online ahead of print Sept. 23, 2025. PMID: 40985694.
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Topics: Radiation , water
Wambaugh JF, Sipes NS, Padilla Mercado G, Arnot JA, Bertato L, Brown TN, Chirico N,…, Patlewicz G , et al. 2026. Collaborative evaluation of in silico predictions for high throughput toxicokinetics. Toxicol In Vitro 110(Jan):106150; doi: 10.1016/j.tiv.2025.106150 . ePub September 20, 2025. PMID: 40983213.
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Topics: toxicokinetics
Klaren WD , Rivera BN , Sheppard AM , Franke K , Wikoff DS . 2025. Approach for systematically assessing study reliability and relevance in evaluations of monosodium glutamate safety. Curr Res Toxicol 9(Sep):100256; doi: 10.1016/j.crtox.2025.100256 . PMID: 41030520.
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Topics: food additives , food safety , Food science
Patlewicz G , Charest N, Ross A, Bledsoe HC, Vidal J, Faramarzi S, Hagan B, Shah I. 2025. Building a compendium of expert driven read-across cases to facilitate an analysis of the contribution that different similarity contexts play in read-across performance. Comput Toxicol 35(Sept):100366; doi: 10.1016/j.comtox.2025.100366 .
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Topics: NAMs
Nyffeler J, Harris FR, Willis C, Byrd G, Blackwell B, Escher BI, Kasparek A, Nichols J,…, Patlewicz G , et al. 2025. A combination of high-throughput in vitro and in silico new approach methods (NAMs) for ecotoxicology hazard assessment for fish. Environ Toxicol Chem 44(9):2599-2621; doi: 10.1093/etojnl/vgae083 . PMID: 39937625.
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Topics: ecotoxicology , NAMs
Nordyke RJ , Patterson JA, Motyka J, March B, Kirson NY, Long G. 2025. The impact of the Inflation Reduction Act’s drug price negotiation program on incentives for clinical development of new drugs. Value Health; doi: 10.1016/j.jval.2025.08.011 . Online ahead of print Sept. 1, 2025. PMID: 40902797.
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Topics: drug development
Baldwin WS, Bloom MS, Chung KW, Dasgupta S, DeLorenzo ME, Hunt KJ, Key PB,…, Jacobellis MA , et al. 2025. Toxicological, chemical, social, and economic challenges associated with PFAS and replacement aqueous film-forming foams (AFFF). Toxics 13(9):732; doi: 10.3390/toxics13090732 .
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Topics: PFAS
Karamertzanis PG, Rasenberg M, Shah I, Patlewicz G . 2025. Modelling in vitro mutagenicity using multi-task deep learning and REACH data. Chem Res Toxicol 38(8):1382-1407; doi: 19.1021/acs.chemrestox.5c00152 . PMID: 40680271.
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Topics: modeling
Muller K, Unice K, Panko J , Ferrari BJD, Breider F, Wagner S. 2025. Risk assessment of tire wear in the environment—A literature review. Environ Sci Process Impacts 27(8):2212-2232; doi: 10.1039/d5em00088b . PMID: 40569214.
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