2025 (29 POSTS)
Reynolds JI , Johnson BP. 2025. AOP 460: Antagonism of Smoothened receptor leads to orofacial clefting. ALTEX; doi: 10.14573/altex.2407121 . Advance online publication August 11, 2025.
View Abstract
Topics: Adverse outcome pathways (AOPs) , NAMs
Proctor D, Jiang X, Reichert H, Thompson C . 2025. Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium. Toxicol Sci kfaf112; doi: 10.1093/toxsci/kfaf112 . Online ahead of print August 8, 2025. PMID: 40795394.
View Abstract
Topics: Cancer , chromium , Exposure Assessment , Hexavalent Chromium , risk assessment
Fitch S , Rogers J , Marty S, Norman J, Schneider S, Rushton E, Wikoff D , Ellis-Hutchings R. 2025. Systematic review of potential developmental and reproductive toxicity of microplastics. Toxicol Sci kfaf108; doi: 10.1093/toxsci/kfaf108 . Online ahead of print August 5, 2025. PMID: 40794567.
View Abstract
Topics: microplastics , Systematic Review , Toxicology
Clouser MC, Suh M , Movva N , Hildebrand JS, Pastula ST, Schoehl M, Hindoyan A, Balasubramanian A, et al. 2025. A systematic literature review of MTAP deletions in solid and hematologic cancers. Cancer Treat Res Comm 44:100966; doi: 10.1016/j.ctarc.2025.100966 .
View Abstract
Topics: Cancer , Systematic Review
Muller K, Unice K, Panko J , Ferrari BJD, Breider F, Wagner S. 2025. Risk assessment of tire wear in the environment—A literature review. Environ Sci Process Impacts; doi: 10.1039/d5em00088b . Online ahead of print June 26, 2025. PMID: 40569214.
View Abstract
Topics: ecotoxicology , Environmental Science , leachables , risk assessment , tire particles (TRWP)
Gauthier A, Behymer W, Bare J, Kramer M , Barranco WT, Longtin JP, Borghoff S , Jaques A. 2025. Measurement of vinyl acetate monomer in consumer products and modeled estimates of consumer exposure. J Exp Sci Environ Epidemiol; doi: 10.1038/s41370-025-00786-y . Online ahead of print June 18, 2025. PMID: 40533479.
View Abstract
Topics: consumer products , Exposure Assessment
Muller K, Unice K, Panko J , Wagner S. 2025. Tire emissions during the use phase of tires – Current and future trends. Environ Sci Adv; doi: 10.1039/d4va00407h . Online ahead of print June 11, 2025.
View Abstract
Topics: tire particles (TRWP)
Brorby G, Franzen A, Thompson C, Wikoff D, Doepker C . 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490 . PMID: 40320068.
View Abstract
Topics: food safety , Food science , genotoxicity , risk assessment , safety assessment , Toxicology
Allen BC, Vincent MJ , Lipworth L, Panko JM, Suh M, Jiang X , Mumma MT, Proctor DM . 2025. Lung cancer risk assessment associated with exposure to hexavalent chromium: Results of pooled analysis of three cohorts. J Occup Environ Hyg; doi: 10.1080/15459624.2025.2502491 . Online ahead of print May 28, 2025. PMID: 40435461.
View Abstract
Topics: Cancer , chromium , Exposure Assessment , Hexavalent Chromium , risk assessment
Diemar MG, Giusti A, Michel-Caillet C, Leme DM, Wikoff D , Bloch D, Sass J, Beekmann K, et al. 2025. How to organize a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024. Arch Toxicol 99(7):3057-3063 ; doi : 10.1007/s00204-025-04064-6 . PMID: 40372420.
View Abstract
Topics: chemical safety assessment , NAMs , risk assessment , safety assessment , Toxicology
Duong T, Haselkorn T, Miller B, Coats J, Jensen I , Ward E, Wood M, Graham RJ, Servais L. 2025. A real-world analysis of the impact of X-linked myotubular myopathy on caregivers in the United States. Orphanet J Rare Dis 20(1):224. doi: 10.1186/s13023-025-03583-w .
View Abstract
Crincoli CM, van de Ligt JLG, Eapen AK. Pavel AT, Hanlon PR, Almond-Abbate K, Haugabrooks E,… Henderson RG . 2025. A tool to support food substance safety evaluations in the United States. Regul Toxicol Pharmacol 161(Sept):105838; doi: 10.1016/j.yrtph.2025.105838 . PMID: 40324559.
View Abstract
Topics: food additives , food safety , Food science , risk assessment
Rogers JM, Heintz MM, Haws LC . 2025. Reproductive and developmental toxicity screen (OECD TG 421) and extended one generation reproductive toxicity study (OECD TG 443) of decahydronaphthalene in Sprague Dawley rats. Regul Toxicol Pharmacol 160(Aug):105829; doi: 10.1016/j.yrtph.2025.105829 . PMID: 40222475.
View Abstract
Topics: Toxicology
Heintz MM , Buerger AN, Haws LC , Cullen JM, East AW, Thompson CM . 2025. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα , PPARγ , and cytotoxic agents in wild-type and Pparα -null mouse livers. Toxicol Sci 206(1):183-201; doi: 10.1093/toxsci/kfaf049 . PMID: 40216583.
View Abstract
Topics: mode of action , Toxicology , transcriptomics
Lipke L, Price C . 2025. Rethinking systematic review assignment design in graduate health science education from librarians’ perspectives. Hypoth: Res J Health Info Prof 37(1); doi: 10.18060/28463 .
View Abstract
Topics: Systematic Review
Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC . 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152 . PMID: 39792025.
View Abstract
Topics: PFAS , risk assessment , Systematic Review , Toxicology
Lea IA , Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221 . PMID: 40041033.
View Abstract
Topics: phthalates
Kramer A , Vivanco S , Bare J , Panko J . 2025. Analysis of EPA air toxics monitoring data and tools for use in general population exposure assessments: Using acrylonitrile as a case study. J Air Waste Manag Assoc 75(3)181-197; doi: 10.1080/10962247.2024.2438793 . PMID: 39660961.
View Abstract