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2022 (27 POSTS)

Goyak KO, Sarang SS, Franzen A, Borghoff SJ, Ryman-Rasmussen JP. 2022. Adverse outcome pathway (AOP): α2u-globulin nephropathy and kidney tumors in male rats. Crit Rev Toxicol, open access.

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Lea IA, Pham LL, Antonijevic T, Thompson C, Borghoff SJ. 2022. Assessment of the applicability of the threshold of toxicological concern for per- and polyfluoroalkyl substances. Regul Toxicol Pharmacol 133:105190, open access.

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Verwiel A, Racz L, Mittal L, Rish W. 2022. CDC’s national report on human exposure to environmental chemicals. SETAC Globe 23(6).

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Keylor MH, Gulati A, Kattar SD, … Ciaccio PJ, et al. 2022. Structure-guided discovery of aminoquinazolines as brain-penetrant and selective LRRK2 inhibitors. J Medicinal Chem 65(1):838–856.

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Racz, L. PFAS: How did we get here and where are we going? Keynote address at Alliance of Hazardous Materials Professionals national meeting, Las Vegas, NV, Mar 2022.

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Rooney J, Abedini J, Bell S, Chang X, Cook B, Ceger P, Choksi N, et al. Building confidence in alternative methods through ICE. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Fitch S, Klaren WD, Payne L, Wikoff D. Comparison of public and private literature databases for toxicological investigations. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Proctor DM, Antonijevic T. Refined health risk assessment for residential exposures to manganese in EAF steel slag. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Klaren WD, Hoberman AM, Hauswirth JW. Reproduction and developmental toxicological evaluation of piperonyl butoxide (PBO). Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Rogers JM, Heintz MM, Thompson CM, Haws LC. Development of a putative adverse outcome pathway for neonatal mortality in rodents: Implications for human health risk assessments of PFAS. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Thompson CM, Chappell GA, Mittal L, Gorman B, Proctor DM, Haws LC, Harris MA. Use of targeted mode-of-action research to inform human health risk assessment of hexavalent chromium. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Chappell G, Wolf JC, Harris MA, Thompson CM. Variation in transcriptomic responses in the crypt and villus of mouse small intestine following oral exposure to hexavalent chromium. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Heintz MM, Chappell GA, Thompson CM, Wolf JC, Rogers JM, Haws LC. HFPO-DA (GenX) transcriptomic responses in pregnant and non-pregnant rat livers: Analyses to inform the role of maternal effects on neonatal toxicity. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Mihalchik A, Wood M. Considerations for standardization and derivation of pediatric and neonatal tolerable exposure limits for extractable and leachable compounds from medical devices. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Dalton C, East A, Price P, Vallero D. The role of product use scheduler for estimating exposure to methyl, ethyl, propyl, and butyl parabenzoic acid (parabens) within the Combined Human Exposure Model. Poster presented at Society of Toxicology, San Diego, CA, March 2022, DOI: 10.23645/epacomptox.1934935, open access online.

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Blanchette AD, Burnett SD, Rusyn I, Chiu WA. 2022. A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability. J Pharmacol Toxicol Methods (In press).

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Fitch S, Klaren WD, LaPlaca, S, Payne L, Wikoff D. Comparison of public and private literature databases for toxicological investigations. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Allen DG, Rooney J, To K, Choksi N, Ceger P, Daniel A, et al. Variability in reference test method data and the impact on NAM evaluations. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Catalano S, Choksi N, Corvaro M, Kolle S, Stinchombe S, Latorre A, et al. Reducing animal use for eye irritation testing of agrochemicals in Brazil. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022

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Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY… Wikoff D, et al. 2022. Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks. ALTEX — Alternatives to animal experimentation, doi: 10.14573/altex.2202141.

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