Publication Topic

Fung ES, Novick RM, Drechsel DA, Towle KM, Novick RM, Paustenbach DJ, Monnot AD. 2019. Tier-based skin irritation testing of hair cleansing conditioners and their constituents. Cutan Ocul Toxicol 38(1):44-47, DOI: 10.1080/15569527.2018.1512610.

Adams R, Brickel J, Bhat VS. 2019. Chemical-specific maximum allowable levels for pesticide residues in dietary supplements. Food Chem Toxicol 123:511-519.

Gollapudi P, Bhat VS, Eastmond D. 2019. Concentration-response studies of the chromosome-damaging effects of topoisomerase II inhibitors determined in vitro using human TK6 cells. Mut Res Gen Toxicol Environ Mutagen 841:49-56.

Monnot AD, Towle KM, Fung ES, Novick RM, Paustenbach DJ, Drechsel DA. 2019. A skin sensitization induction risk assessment of common ingredients present in commercially available cleansing conditioners. Dermatitis 30(2):116–128.

Benson SM, Maskrey JR, Nembhard MD, Unice KM, Shirley MA, Panko JM. 2019. Evaluation of personal exposure to surgical smoke generated from electrocautery instruments: A pilot study. Ann Work Expos Health wxz070; open access.

Krelder ML, Unice KM, Panko JM. 2019. Human health risk assessment of tire and road wear particles (TRWP) in air. Hum Ecol Risk Assess, open access.

Chappell GA, Borghoff SJ, Pham L, Doepker CL, Wikoff DS. 2019. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol (in press).

Wikoff DS, Chappell GA, Fitch S, Doepker CL, Borghoff SJ. 2019. Lack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol (in press).

Thompson C, Chappell G, Cullen J, Wolf JC, Haws L. Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic Meeting, Durham, NC, August 2019.

Chappell GA, Thompson CM, Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.

Thompson CM. The useful chemistry of perfluorinated compounds: Managing safety. The sticky subject of non-stick: Regulatory science challenges of per- and poly-fluorinated compounds (PFAS). Texas A&M University Interdisciplinary Faculty of Toxicology Training Program, 2019 Annual Regulatory Science Symposium. August 20, 2019.

Andersen ME, Gentry PR, Swenberg JA, Mundt KA, White KW, Thompson C, Bus J, Sherman JH, Greim H, Bolt H, Marsh GM, Checkoway H, Coggon D, Clewell HJ. 2019. Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop. Regul Toxicol Pharmacol 106:210–223.

Clewell RA, Thompson CM, Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301:112–127.

Chappell G, Rager J, Wolf J, Babic M, Leblanc, Ring C, Harris MA, Thompson CM. 2019. Comparison of gene expression responses in the small intestine of mice following exposure to three carcinogens using the S1500+ gene set informs a potential common adverse outcome pathway. Toxicol Pathol 47(7):851-864.

van de Ligt J, Borghoff SJ, Yoon M, Ferguson LJ, DeMaio W, McClanahan RH. 2019. Nondetectable or minimal detectable residue levels of N-(n-butyl) thiophosphoric triamide in bovine tissues and milk from a 28-d NBPT dosing study. Translat An Sci 3(4).

Mease K. Managing immunogenicity in the absence of an ADA assay is no monkey business (case study). Presentation at 25^th annual Charles River Biotech Symposium, Carlsbad, CA, September 8–11, 2019.

Lansita J, Weis S. A peek into the black box—Insight from former FDA reviewers on the BLA review process. Presentation at 25^th annual Charles River Biotech Symposium, Carlsbad, CA, September 8–11, 2019.

Thompson CM, Fitch SE, Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol 39:1267–1282.

Yoon M, Ring C, Van Landingham CB, Suh M, Song G, Antonijevic T, Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380:114695

Pham LL, Watford S, Friedman KP, Fostel J, Wignall J, Shapiro A. 2019 (in press). Python BMDS: A Python interface library and web application for the canonical EPA dose-response modeling software. Reprod Toxicol (journal pre-proof).

Watford S, Pham LL, Brown J, Wignall J, Shin R, Martin M, Friedman KP. 2019. ToxRefDB 2.0: Improved utility for predictive and retrospective toxicology analyses. Reprod Toxicol 89:145–158. doi: 10.1016/j.reprotox.2019.07.012.

Pham LL, Truong L, Ouedraogo G, Loisel-Joubert S, Martin MT, Friedman KP. 2019. Profiling 58 compounds including cosmetic-relevant chemicals using ToxRefDB and ToxCast. Food Chem Toxicol 132:110718. doi: 10.1016/j.fct.2019.110718.

Ring CL, Arnot JA, Bennett DH, Egeghy PP, Fantke P, Huang L, Isaacs KK, Jolliet O, Phillips KA, Price PS, Shin H-M, Westgate JN, Setzer RW, Wambaugh JF. 2019. Consensus modeling of median chemical intake for the U.S. population based on predictions of exposure pathways. Environ Sci Technol 53:719–732.

Hopkins B, Cohen SS, Irvin SR, Alberda C. 2019. Achieving protein targets in the ICU using a specialized high-protein enteral formula: A quality improvement project. Nutr Clin Practice, DOI: 10.1002/ncp.10364 – Hopkins_Cohen_NCP_2019.

Unice KM, Weeber MP, Abramson MM, Reid RCD, van Gils JAG, Markus AA, Vethaak AD, Panko JM. 2019. Characterizing export of land-based microplastics to the estuary – Part II: Sensitivity analysis of an integrated geospatial microplastic transport modeling assessment of tire and road wear particles. Sci Tot Environ 646:1650–1659.

Unice KM, Weeber MP, Abramson MM, Reid RCD, van Gils JAG, Markus AA, Vethaak AD, Panko JM. 2019. Characterizing export of land-based microplastics to the estuary — Part I: Application of integrated geospatial microplastic transport models to assess tire and road wear particles in the Seine watershed. Sci Tot Environ 646:1639–1649.

Panko JM, Hitchcock KM, Fuller GW, Green D. 2019. Evaluation of tire wear contribution to PM2.5 in urban environments. Atmosphere 10(2):99, https://doi.org/10.3390/atmos10020099.

Wikoff D, Haws L, Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol, doi: 10.1002/jat.3814, open access.

Wikoff D, Erranguntla N, Lewis J, Foreman J. A fit-for-purpose framework for use of systematic methods in risk assessment. Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Urban J, Wikoff D, Haws L. Three-tiered approach to integrating evidence streams assessing gestational trichloroethylene exposure and congenital heart defects (TCE-CHD). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine. Washington, DC, June 2019.

Borghoff S, Fitch S, Britt J, Franke K, Wikoff D. Application of the EFSA/ECHA endocrine disruption guidance as a framework for evidence integration in a weight-of-evidence (WoE) analysis for oxybenzone (BP-3). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Kreider ML, Hynds ES, Panko JM. Evaluation of tire and road wear particles (TRWP) in air in Delhi, India. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 10–14, 2019.

Honda GS, Pearce RG, Pham LL, Setzer RW, Wetmore BA, Sipes NS, Gilbert J, Franz B, Thomas RS, Wambaugh JF. 2019. Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions. PLoS ONE 14(5):e0217564.

Pham LL, Sheffield T, Pradeep P, Brown J, Haggard D, Wambaugh J, Judson R, Friedman KP. 2019. Estimating uncertainty in the context of new approach methodologies for potential use in chemical safety evaluation. Curr Opin Toxicol 15:40-47.

Chamberlain AM, Cohen SS, Weston SA, Fox KM, Xiang P Killian JM Qian Y. 2019. Relation of cardiovascular events and deaths to low-density lipoprotein cholesterol level among statin-treated patients with atherosclerotic cardiovascular disease. Am J Cardiol 123(11):1739-1744.

Storm HM, Shepard J, Czerkies LM, Kineman B, Cohen SS, Reichert H, Carvalho R. 2019. 2’-Fucosyllactose is well tolerated in a 100% whey, partially hydrolyzed infant formula with Bifidobacterium lactis: A randomized controlled trial. Global Pediat Health 6:1–10. DOI: 10.1177/2333794X19833995.

Klosterbuer A, Neutel JM, Cohen SS, Periman S. Plasma glucose and insulin response to high protein oral nutritional supplements in adults with type 2 diabetes mellitus. Poster at ASPEN 2019 Nutrition Science & Practice Conference, March 2019, Phoenix, AZ.

Gentry R, Greene T, Granzen A, Thompson CM. Formaldehyde and leukemia: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Urban J, Wikoff D, Suh M, Britt J, Harvey S, Chappell G, Haws L. Comparison of NTP OHAT and US EPA TSCA study quality criteria: Trichloroethylene (TCE) and congenital heart defects (CHDs) as a case study. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

McIntyre B, Zorilla L, Borghoff, S, Foster P. Assessment of avobenzone, ensulizole, homosalate, and padimate-O in endocrine disruptor screening panel studies. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Thompson CM, Gentry R. An updated mode-of-action analysis for formaldehyde-induced nasal tumors in rodents: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Borghoff SJ, Fitch S, Huggett, Wikoff D. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA). 2019. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Saili KS, Zurlinden TH, Antonijevic T, Shah I, Deisenroth C, Knudsen TB. Endodermal differentiation trajectories diverge with increasing all-trans retinoic acid (ATRA) exposure. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Yoon M, Ring C, Van Landingham CV, Gentry PR, Taylor MD, Keene AM, Clewell HJ. Assessing early life drinking water exposures to manganese (Mn). Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C. Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Suh M, Casteel S, Dunsmore M, Ring C, Verwiel A, Proctor DM. 2019. Bioaccessibility and relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Sci Tot Environ 660:677–689.

Kimzey AL, Piche M-S, Wood M, Weir AB, Lansita J. 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3^rd Ed. Vol 11:399–427.

Hughes B, Cox K, Bhat VS. 2018. Derivation of an oral reference dose (RfD) for di-2-ethylhexyl cyclohexan-1,4-dicarboxylate (DEHCH), an alternative to phthalate plasticizers. Regul Toxicol Pharmacol 92:128-137.

Drechsel DA, Barlow CA, Bare JL, Jacobs NF, Henshaw JL. 2018. Historical evolution of regulatory standards for occupational and consumer exposures to industrial talc. Regul Toxicol Pharm 91:251–267.

Towle KM, Drechsel DA, Fung E, Novick RM, Paustenbach DJ, Monnot AD. 2018. A quantitative risk assessment of the skin sensitization induction potential of the Kathon CG preservative in rinse-off and leave-on personal care and cosmetic products. Dermatitis 29(3):132–138.

Drechsel DA, Towle KM, Fung E, Novick RM., Paustenbach DJ, Monnot AD. 2018. Chemical stability analysis of hair cleansing conditioners under high-heat conditions experienced during hair styling processes. Cosmetics 5(1):23.

Fung ES, Drechsel DA, Towle KM, Hoang MT, Novick RM, Poteete C, Paustenbach DJ, Monnot AD. 2018. Screening-level safety assessment of personal care product constituents using publicly available data. Cosmetics 5(2):38.

Drechsel DA, Towle KM, Fung E, Novick RM., Paustenbach DJ, Monnot AD. 2018. Evaluation of skin sensitization induction potential from daily exposure to fragrances in personal care products. Dermatitis 29(6):324–331.

Borghoff SJ, Fitch S, Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99:168–181.

Ring CL, Suh M, Casteel S, Dunsmore M, Verwiel A, Proctor D. Relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.

Harrill AH, Borghoff S, Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ. 2018. NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies. National Toxicology Program Research Report 6, Research Triangle Park, NC.

Klaren WD, Ring C, Harris MA, Thompson CM, Borghoff S, Sipes NS, Hsieh J-H, Auerbach SS, Rager JE. 2018. Identifying attributes that influence in vitro-to-in vivo concordance by comparing in vitro Tox21 bioactivity versus in vivo DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci kfy220, available at https://doi.org/10.1093/toxsci/kfy220.

Wikoff DS, Thompson C, Rager J, Chappell G, Fitch S, Doepker C. 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120:709-723.

Benson SM, Maskrey JR, Nembhard M, Panko JM. Characterization of surgical smoke generated from electrocautery instruments: A pilot study. Poster at the 2018 American Occupational Health Conference (AOHC) 103rd Annual Meeting, New Orleans, LA, April 29 – May 2, 2018.

Wikoff DS, Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337.

Thompson CT, Suh M, Chappell G, Borghoff S, Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor, DM. 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189 doi: 10.1016/j.yrtph.2018.05.006.

Suh M, Proctor DM, Chappell G, Rager JE, Thompson CM, Borghoff S, Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicology 402-403:50-67, doi: 10.1016/j.tox.2018.04.006.

Proctor DM, Suh M, Chappell G, Borghoff SJ, Thompson CM, Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol, 96:30-40, doi: 10.1016/j.yrtph.2018.04.016.

Brorby GP. 2018. The ongoing controversy surrounding the effects of short-term exposure to trichloroethene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, March 19–22, San Diego, CA.

Wikoff D, Urban JD, Harvey S, Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol, DOI: 0.1177/1091581818754330.

Bhat VS, Meek B (M.E.), Valcke M, EnglishJC, Boobis AR, Brown RJ. 2017. Evolution of chemical-specific adjustment factors (CSAF) based on recent international experience; increasing utility and facilitating regulatory acceptance. Crit Rev Toxicol 47:733-753.

Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C, Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; DOI: 10.1021/acs.chemrestox.7b00221.

Panko J, Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. A comparative evaluation of five hazard screening tools. Integr Environ Assess Manag 13(1):139–154.

See also: Panko J, Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. Letter to the Editor: Authors’ response to Turner et al. Integr Environ Assess Manag 13(1):15–16.

Perez AL, Gauthier AM, Ferracini T, Cowan DM, Kingsbury T, Panko J. 2017. The challenge of predicting problematic chemicals using a decision analysis tool: Triclosan as a case study. Integr Environ Assess Manag 13(1):198–207.

Burns A, Shin J, Unice KM, Gaffney SH, Kreider ML, Gelatt RN, Panko JM. 2017. Combined analysis of job and task benzene air exposures among workers at four US refinery operations. Toxicol Indust Health 33(3):193–210.

Ring CL, Pearce RG, Setzer RW, Wetmore BA, Wambaugh JF. 2017. Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability. Environ Int 106:105–118.

Bichteler A, Wikoff DS, Loko F, Harris MA. 2017. Estimating serum concentrations of dioxin-like compounds in the U.S. population effective 2005-2006 and 2007-2008: A multiple imputation and trending approach incorporating NHANES pooled sample data. Environ Int 105(2017):112-125.

Kirman CR, Suh M, Proctor DM, Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325:9-17.

Wikoff DS, Rager J, Harvey S, Haws L, Chappell G, Borghoff S. 2017. Framework for quantitative consideration of study quality and relevance in the systematic evaluation of mechanistic data per the Ten Key Characteristics of Carcinogens. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

Thompson CM, Wolf, JC, McCoy A, Suh M, Proctor DM, Kirman CR, Haws LC, Harris MA. 2017. Comparison of toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens captan, folpet, and hexavalent chromium. Toxicol Pathol 45(8):1091–1101. DOI: 10.1177/019262331yy4324.

Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Chjoksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS. 2017. In vitro to in vivo extrapolation for high throughput prioritization and decision making. Toxicol in Vitro 47:213–227.

Lake AD, Wood CD, Bhat VS, Chorley BN, Carswell GK, Sey Y, Kenyon EM, Padnos B, Moore TM, Tennant AH, Schmid JE, George BJ, Ross DG, Hughes MG, Corton JC, Simmons JE, McQueen CA, Hester SD. 2016. Dose and effect thresholds for early key events in a PPARα-mediated mode of action. Toxicol Sci 149:312-325.

Hester SD, Bhat VS, Chorley BN, Carswell G, Jones W, Ward W, Wehmas L, Wood CE. 2016. Editor’s Highlight: Dose-response analysis of RNA-seq profiles in archival formalin-fixed paraffin-embedded (FFPE) samples. Toxicol Sci 154:202-213.

Borghoff SJ, Ring C, Banton M, Leavens TL. 2016. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes.  J Appl Toxicol, DOI 10.1002/jat.3412

Panko JM, Benson SM, Kreider ML. Meta-analysis of lung cancer risk related to diesel exposure by occupation and evaluation of exposure response. Abstract #2976. Poster at Society of Toxicology Annual Meeting, New Orleans,LA, March 13–17, 2016.

Gloekler L, Shay EC, Schmidt N, Haghighat B, Panko JM, Cowan DM, Paustenbach DJ. Flame-retardants in upholstered furnishings: An assessment of health risk and fire-related deaths in the era of California Technical Bulletin (TB-117). Abstract #2669. Poster at Society of Toxicology Annual Meeting, New Orleans, LA, March 13–17, 2016.

Maskrey JR, Insley A, Hynds ES, Panko JM. 2016. Air monitoring of volatile organic compounds at relevant receptors during hydraulic fracturing operations in Washington County, Pennsylvania. Environ Monit Assess 188(7):1–12, Article 410.

Wikoff DS, Britt JK.  2016. The role of systematic review in the practice of toxicology and risk assessment – An appreciation for the primary tool in evidence-based approaches.  Toxicology: Open Access 2(110):1-4. 

Schmitt D, Levy R, Carroll B. 2016. Toxicological evaluation of ß-caryophyllene oil: Subchronic toxicity in rats. Int J Toxicol 35(5):558–567.

Hester S, Eastmond DA, Bhat VS. 2015. Developing toxicogenomics as a research tool by applying benchmark dose-response modeling to inform chemical mode of action and tumorigenic potency. Invited Contribution, Special Issue on Toxicogenomics: The emergence of a new research and regulatory paradigm. Inter J Biotechnol 14:28-46.

Brorby G, Suh M, Bichteler A, Proctor D. Use of cluster analysis and homogeneity testing to characterize distributions of exposures among beryllium workers: Tools for developing occupational exposure limits from quantitative risk assessment.  Presented at International Society of Exposure Science 25th Annual Meeting, Henderson, NV, October 18-22, 2015.

Mason AM, Spencer PJ, Panko JM. A pilot project reveals prominent hazard screening tools fall short on performance expectations. Poster at the 54th Annual Meeting and Society of Toxicology (SOT) Meeting, San Diego, CA, March 22–26, 2015.

Panko JM, Hitchcock KM, Fung M, Spencer PJ, Kingsbury T, Mason AM. A comparative evaluation of seven hazard screening tools. Poster at 25th Annual Meeting of NorCal SETAC, Sacramento, CA, April 29–30, 2015.

Panko JM, Hitchcock KM. From critical reviews of hazard assessment tools to building a product evaluation framework: Can we bridge the gaps with a super tool? Presentation at the American Industrial Hygiene Conference & Expo (AIHce), Salt Lake City, UT, May 30 – June 4, 2015.

Unice KM, Bare JL, Kreider ML, Panko JM. Evaluation of leachate from tire and road wear particles (TRWP) upflow percolation column tests. Poster at Society of Environmental Toxicology and Chemistry, 36th Annual Meeting, Salt Lake City, UT, November 1–5, 2015.

Gauthier AM, Fung M, Panko J, Kingsbury T, Perez AL, Hitchcock K, Ferracini T, Sahmel J, Banducci A, Jacobsen M, Abelmann A, Shay E. 2015. Chemical assessment state of the science: Evaluation of 32 decision-support tools used to screen and prioritize chemicals. Integr Environ Assess Manag 11(2):242–255.

Kreider ML, Cyrs WD, Tosiano MA, Panko JM. 2015. Evaluation of quantitative exposure assessment method for nanomaterials in mixed dust environments: Application in tire manufacturing facilities. Ann Occup Hyg
59(9):1122–1134.

Ramani T, Auletta CS, Weinstock D, Mounho-Zamora B, Ryan PC, Salcedo TW, Bannish G. 2015. Cytokines: The good, the bad, and the deadly. Int J Toxicol 34(4):355–365, DOI 10.1177/1091581815584918.

Wikoff D, Thompson C, Perry C, White M, Borghoff S, Fitzgerald L, Haws LC. 2014. Development of toxicity values and exposure estimates for tetrabromobisphenol A [TBBPA]: Application in a margin of exposure assessment. J Appl Toxicol 35(11):1292-1308. doi: 10.1002/jat.3132.

Geter DR, Bhat VS, Gollapudi BB, Sura R, Hester SD. 2014. Dose-response modeling of early molecular and cellular key events in the CAR-mediated hepatocarcinogenesis pathway. Toxicol Sci 138:425-445.

Wood CE, Jokinen MP, Johnson CL, Olson GR, Hester S, George M, Chorley B, Carswell G, Carter JH, Wood CR, Bhat VS, Corton JC, DeAngelo AB. 2014. Comparative time course profiles of phthalate stereoisomers in mice. Toxicol Sci 139:21-34.

Bhat VS, Durham JL, Ball GL, English JC. 2014. Derivation of an oral reference dose (RfD) for the non-phthalate alternative plasticizer, 1,2-cyclohexane dicarboxylic acid, di-isononyl ester (DINCH®). J Toxicol Environ Health B Crit Rev 17:63-94.

Bhat VS, Durham JL, English JC. 2014. Derivation of an oral reference dose (RfD) for the plasticizer, di-(2-propylheptyl)phthalate (Palatinol® 10-P). Regul Toxicol Pharmacol 70:65-74.

Chang CH, Drechsel DA, Kitson RA, Siegel D, You Q, Backos DS, Ju C, Moody CJ, Ross DR. 2014. 19-Substituted benzoquinone ansamycin heat shock protein-90 inhibitors: Biological activity and decreased off-target toxicity. Molec Pharmacol 85(6):849–857.

Johnson GE, Soeteman-Hernandez, Gollapudi BB, Bodger OG, Dearfield KL, RH Heflich, Hixon JG, Lovell DP, MacGregor JT, Pottenger LH, Thompson CM, Abraham L, Thybaud V, Tanir JY, Zeiger E, van Benthem J, White PA. 2014. Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment. Environ Molec Mutagen 55(8):609-623. doi: 10.1002/em.21870/em.21870.

Panko JM. Green chemistry: A critical element of sustainable development and product stewardship. Presentation at The American Industrial Hygiene Conference & Exposition (AIHce), San Antonio, TX, May 31 – June 5, 2014.

Kreider ML, Cyrs WD, Tosiano MA, Panko JM. Method development for nanomaterials exposure assessment in mixed dust environments. Presentation at The American Industrial Hygiene Conference & Exposition (AIHce), San Antonio, TX, May 31 – June 5, 2014.

Cyrs WD, Tosiano MA, Panko JM, Kreider ML. Use of a novel method to assess exposure to nanoscale carbon black and amorphous silica at two tire manufacturing facilities. Presentation at The American Industrial Hygiene Conference & Exposition (AIHce), San Antonio, TX, May 31 – June 5, 2014.

Panko JM. Chemical selection tools analysis project & results. Presented at GlobalChem. Global Chemical Regulations Conference, Baltimore, MD, March 3–5, 2014.

Faber W, Kirkpatrick D, Coder P, Li P, Borghoff S, Banton M. 2014. Subchronic, reproductive, and maternal toxicity studies with tertiary butyl acetate (TBAC). Regul Toxicol Pharmacol 68:332-342.

Song G, Darr DB, Santos CM, Ross M, Valdivia A, Jordan JL, Midkiff BR, Cohen S, Feinberg NN, Miller CR, Tarrant TK, Rogers AB, Dudley AC, Perou CM, Zamboni WC. 2014. Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models. Clin Cancer Res 20(23):6083–6095.

Suh M, Troese MJ, Hall DA, Yasso B, Yzenas JJ, Proctor DM. 2014. Evaluation of electric arc furnace-processed steel slag for dermal corrosion, irritation, and sensitization from dermal contact. J Appl Toxicol 34(12):1418-1425. DOI: 10.1002/jat.2974.

Willhite CC, Ball GL, Bhat VS. 2013. Emergency do not consume/do not use concentrations for blended phosphates in drinking water. Human Exper Toxicol 32:241-259.

Willhite CC, Bhat VS, Ball GL, McLellan CJ. 2013. Emergency do not consume/do not use concentrations for potassium permanganate in drinking water. Human Exper Toxicol 32:275-298.

Willhite C, Ball GL, Bhat VS. 2013. Emergency do not consume/do not use concentrations for ferric chloride in drinking water. Human Exper Toxicol 32:260-274.

Bhat VS, Hester SD, Nesnow S, Eastmond DA. 2013. Concordance of transcriptional and apical benchmark dose levels for conazole-induced liver effects in CD-1 mice. Toxicol Sci 136:205-215.

Tosiano MA, Panko JM, Scott PK. Risk based evaluation of the chemical constituents in hydraulic fracturing fluid using the chemical disclosure registry FracFocus. Poster at Society of Environmental Toxicology and Chemistry, 34th Annual Meeting, Nashville, TN, November 11–14, 2013.

Shay EC, Panko JM. Community-focused remediation and risk assessment at a former manufactured gas plant site. Poster at Society of Environmental Toxicology and Chemistry, 34th Annual Meeting, Nashville, TN, November 11–14, 2013.

Panko JM, Chu J, Kreider ML, Unice KM. 2013. Measurement of airborne concentrations of tire and road wear particles in urban and rural areas of France, Japan, and the United States. Atmos Environ 72:192–199.

Gross SA, Avens HJ, Banducci AM, Sahmel J, Panko JM, Tvermoes BE. 2013. Analysis of BTEX groundwater concentrations from surface spills associated with hydraulic fracturing operations. J Air Waste Manage Assoc 63(4):424–432.

Kreider ML, Burns AM, DeRose GH, Panko JM. 2013. Protecting workers from risks associated with nanomaterials: Part II — Best practices in risk management. Occup Safety Health 82(9):20–24.

Kreider ML, Burns AM, DeRose GH, Panko JM. 2013. Protecting workers from risks associated with nanomaterials: Part I — Exposure assessment. Occup Safety Health 82:7.

Unice KM, Kreider ML, Panko JM. 2013. Comparison of tire and road wear particle concentrations in sediment for watersheds in France, Japan, and the United States by quantitative pyrolysis GC/MC analysis. Environ Sci Technol 47(15):8138–8147.

Drechsel DA, Estevez AG, Barbeito L, Beckman JS. 2012. Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS. Neurotoxicol Res 22(4):251–264.

Suh M, Ke JG, Hixon G, Proctor DM. Urinary perchlorate, nitrate, thiocyanate and thyroid hormone levels in participants of National Health and Nutrition Examination Survey (NHANES) 2001-2002. Presented at the International Society of Environmental Epidemiology’s 24th Annual Meeting, Columbia, SC, August 26-30, 2012.

Kreider ML, Panko JM, Finley BL. 2012. Effects of subacute inhalation exposure to tire and road wear particles in rats. Presented at the 2012 Health Effects Institute (HEI) Annual Conference, Chicago, IL, April 15–17, 2012.

Kreider ML, Panko JM. Effects of subacute inhalation exposure to tire and road wear particles in rats. Presented at Eurotox 2012, Stockholm, Sweden, June 17–20, 2012.

Kreider ML, Unice KM, Panko JM. A case study in understanding exposure associated with nanostructured materials: Carbon black and amorphous silica. Presented at SETAC Asia/Pacific 2012 Meeting, Kumamoto, Japan, September 24–27, 2012.

Sahmel J, Cowan DM, Panko JM, Paustenbach DJ. 2012. Future trends in risk management: Control banding and REACH. Chapter 19 in: Perkins J, Gray C. (eds). Modern Industrial Hygiene, Volume III: Control of Chemical Agents, Part IV: Risk Management. ACGIH, Cincinnati, OH, pp. 727–764.

Panko JM, Kreider ML, McAtee BL, Marwood C. 2012. Chronic toxicity of tire and road wear particles to water- and sediment-dwelling organisms. Ecotoxicology 22(1):13–21, doi: 10.1007/s10646-012-0998-9.

Kreider ML, Doyle-Eisele M, Russell RG, McDonald JD, Panko JM. 2012. Evaluation of potential for toxicity from subacute inhalation of tire and road wear particles in rats. Inhal Toxicol 24(12):907–917.

Unice KM, Kreider ML, Panko JM. 2012. Use of a deuterated internal standard with pyrolysis-GC/MS dimeric marker analysis to quantify tire tread particles in the environment. Int J Environ Res Pub Health 9:4033–4055.

Henderson RG, Durando J, Oller A, Merkel DJ, Marone PA,  Bates HK. 2012. Acute oral toxicity of nickel compounds. Regul Toxicol Pharmacol 62(3):425-432.

Cantu D, Fulton RE, Drechsel DA, Patel M. 2011. Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and hydrogen peroxide. J Neurochem 118(1):79–92.

Kreider ML, Panko JM, McDonald JD, McAtee BL, Finley BL, Seagrave J. Effects of intratracheal instillation of tire and road wear particles (TRWP) and tread particles (TP) on inflammation and cytotoxicity in rat lung: A comparative toxicity study. Society of Toxicology Annual Meeting, Baltimore, MD, March 2011.

Gaffney SH, Panko JM, Unice KM, Burns AM, Kreider ML, Gelatt RH, Booher LE, Paustenbach DJ. 2011. Occupational exposure to benzene at the ExxonMobil refinery in Baytown, TX (1978-2006). J Exp Sci Environ Epidemiol 21:169–185.

Drechsel DA, Patel M. 2010. Respiration-dependent hydrogen peroxide removal in brain mitochondria via the thioredoxin/peroxiredoxin system. J Biol Chem 285(36):27850–27858.

Panko JM, Kreider ML, Ferrara J. REACH – A review of the regulation and technical components of registration. AIHA Pittsburgh Section, Pittsburgh, PA, February 28, 2010.

Kreider ML, Panko JM, McAtee BL, Sweet LI, Finley BL. 2010. Physical and chemical characterization of tire-related particles: Comparison of particles generated using different methodologies. Sci Total Environ
408(3):652–659.

Gaffney SH, Burns AM, Kreider ML, Unice KM, Widner TE, Paustenbach DJ, Booher LE, Gelatt RN, Panko JM. 2010. Occupational exposure at the ExxonMobil refinery in Beaumont, TX (1976-2007). Int J Hyg Environ Health 213(4):285–301.

Drechsel DA, Patel M. 2009. Differential contribution of the mitochondrial respiratory chain to reactive oxygen species production by redox cycling herbicides implicated in parkinsonism. Toxicol Sci 112(2):427–434.

Panko JM. Progress on a BEEL Guide for d-limonene. Roundtable #224, American Industrial Hygiene Conference and Exhibition, Toronto, ON, June 1–4, 2009.

Panko JM, Gaffney SH, Kreider ML, Unice KM, Burns AM, Paustenbach DJ, Booher LE, Gelatt RH. Job and task based analysis of benzene air concentrations associated with refinery operations. Benzene 2009: Health Effects and Mechanisms of Bone Marrow Toxicity; Implications for t-AML and the Mode of Action Framework, Munich, Germany, September 2009.

Williams ES, Panko JM, Paustenbach DJ. 2009. The European Union’s REACH Regulation: A review of its history and requirements. Crit Rev Toxicol 39(7):553–575.

Panko JM, Gaffney SH, Burns AM, Unice KM, Kreider ML, Booher LE, Gelatt RH, Marshall JR, Paustenbach DJ. 2009. Occupational exposure to benzene at the ExxonMobil Refinery at Baton Rouge, Louisiana (1977–2005). J Occup Environ Hyg 6:517–529.

Gaffney SH, Panko JM, Unice KM, Burns AM, Kreider ML, Gelatt RH, Booher LE, Paustenbach DJ. 2009. Occupational exposure to benzene at the ExxonMobil Refinery in Baytown, TX (1978-2006). J Expos Sci Environ Epidemiol 21:169­185.

Drechsel DA, Patel M. 2008. Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson’s disease. Free Radic Biol Med 44(11):1873–1886.

Panko JM, Gaffney SH, Unice KM, Kreider ML, Burns AM, Widner TE, Booher LE, Gelatt GL, Paustenbach DJ. Benzene exposures of refinery workers: Baytown, TX (1978-2006). American Industrial Hygiene Conference and Exhibition, June 2008.

Gaffney SH, Kreider ML, Unice KM, Burns AM, Paustenbach DJ, Booher LE, Gelatt RH, Panko JM. Benzene exposure in refinery workers (1976-2006). Abstract #864, International Society for Environmental Epidemiology & International Society of Exposure Analysis 2008 Joint Annual Conference, Pasadena, CA, October 12–16, 2008.

Sampey BP, Carbone DL, Doorn JA, Drechsel DA, Petersen DR.  2007. 4-Hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (Erk) and the inhibition of hepatocyte Erk-Est-like protein-1-activating protein-1 signal transduction. Molec Pharmacol 71(3):871883.

Drechsel DA, Liang LP, Patel M. 2007. 1-Methyl-4-phenylpyridinium-induced alterations of glutathione status in immortalized rat dopaminergic neurons. Toxicol Appl Pharmacol 220(3):341–348.

Castello PR, Drechsel DA, Patel M. 2007. Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. J Biol Chem 282(19):14186–14193.

Sampey BP, Carbone DL, Doorn JA, Drechsel DA, Petersen DR.  2007. 4-Hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (Erk) and the inhibition of hepatocyte Erk-Est-like protein-1-activating protein-1 signal transduction. Molec Pharmacol 71(3):871883.

Drechsel DA, Liang LP, Patel M. 2007. 1-Methyl-4-phenylpyridinium-induced alterations of glutathione status in immortalized rat dopaminergic neurons. Toxicol Appl Pharmacol 220(3):341–348.

Castello PR, Drechsel DA, Patel M. 2007. Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. J Biol Chem 282(19):14186–14193.

Castello PR, Drechsel DA, Day BJ, Patel M. 2007. Inhibition of mitochondrial hydrogen peroxide production by lipophilic metalloporphyrins. J Pharma Exp Ther 324(3):970–976.

Panko JM, Unice KM, Shay EC. Javier AF. Assessment of children’s exposures to toluene. Society of Toxicology Conference, March 2007.

Gaffney SH, Widner TE, Paustenbach DJ, Panko JM, Brown JL, Unice KM. Historical benzene exposure reconstruction: Refinery workers at ExxonMobil Refinery, Baton Rouge, Louisiana (1978-2005). American Industrial Hygiene Conference and Exhibition, June 2007.

Williams PRD, Panko JM, Unice KM, Brown JL, Paustenbach DJ. 2007. Benzene exposures from petroleum-derived solvents containing trace levels of benzene in occupational settings. American Industrial Hygiene Conference and Exhibition, June 2007.

Panko JM, Unice KM, Shay EC. 2007. Recommendations for developing child-focused exposure assessments based on VCCEP experiences. Society for Risk Analysis, December 2007.

Paustenbach DJ, Panko JM, Scott PK, Unice KM. 2007. A methodology for estimating human exposure to perfluorooctanoic acid (PFOA): A retrospective exposure assessment of a community (1951-2003). J Toxicol Environ Health A 70(1):28–57.

Paustenbach DJ, Gaffney SH, Scott PK, Brown JL, Panko JM. 2007. Commentary: High background levels of urinary benzene metabolites found in a volunteer study. J Occup Environ Hyg 4:D71–D77.

Paustenbach DJ, Gaffney SA, Scott PK, Brown JL, Panko JM. High background levels of urinary benzene metabolites found in volunteer study. Society of Toxicology Conference 2006.

Paustenbach DJ, Panko JM, Scott PK, Unice KM. Retrospective modeling of potential residential exposure to perfluorooctanoic acid (PFOA) releases from a manufacturing facility. Society of Toxicology Conference 2006.

Panko JM, Shay EC. Potential for airborne dispersion of bromadiolone and exposure in an office setting. International Society for Exposure Assessment Conference 2006.

Panko JM, Unice KM, Shay EC, Price P. Assessment of children’s exposures to xylenes. International Society for Exposure Assessment Conference 2006.

Panko JM, Unice KM, Shay EC, Javier AF. 2006. Assessment of children’s exposures to benzene. Society for Risk Analysis, December 2006.

Yoon MY, Lee SJ, Lee BH, Chung JH, Kim YC. 2006. Effects of dimethylsulfoxide on metabolism and toxicity of acetaminophen in mice. Biol Pharmaceut Bull 29(8):1618–1624.

Unice KM, Panko JM, Scott PK. Considerations for reconstruction of TCE exposure from groundwater vapor intrusion. International Society for Exposure Assessment Conference 2005.

Unice KM, Panko JM, Scott PK. Development of exposure assessment models for indoor air exposure to elemental mercury. International Society for Exposure Assessment Conference, 2005.

Panko JM, Unice KM, Brown JL. Comparison of toluene exposures during spray painting using various consumer product exposure models. International Society for Exposure Assessment Conference 2005.

Panko JM, Unice KM, Shay EC, Price P. 2004. Childhood exposure assessment of acetone. International Society for Exposure Assessment 2004.

Proctor DM, Panko JM, Liebig EW, Paustenbach DJ. 2004. Estimating historical occupational exposure to airborne hexavalent chromium in a chromate production plant: 1940–1972. J Occup Environ Hyg 1(11):752–767.

Panko JM, Shay EC, Unice KM. Risk perception: The reoccupancy of Lower Manhattan office space following the national tragedies of September 11, 2001. Poster at the Society for Risk Analysis Annual Conference, December 2003.

Proctor DM, Panko JM, Liebig EW, Mundt KA, Buczynski MA, Barnhart RJ, Harris MA, Morgan RJ, Finley BL, Paustenbach DJ. 2003. Workplace airborne hexavalent chromium concentrations for the Painesville, Ohio chromate production plant (1943–1971). Appl Occup Environ Hyg 18(6):430–449.

Luippold RS, Mundt KA, Austin RP, Liebig EW, Panko JM, Crump C, Crump K, Proctor DM. 2003. Lung cancer mortality among chromate production workers. J Occup Environ Med 60:451–457.

Crump C, Crump K, Hack E, Luippold R, Mundt K, Liebig EW, Panko JM, Paustenbach DJ, Proctor DM. 2003. Dose-response and risk assessment of airborne hexavalent chromium and lung cancer mortality. Risk Anal 23(6):1147–1163.

Paustenbach DJ, Panko JM, Fredrick MM, Finley BL, Proctor DM. 1997. Urinary chromium as a biological marker of environmental exposure: What are the limitations? Regul Toxicol Pharmacol 26(1 Pt 2):S23–S34.

Finley BL, Burton S, Panko JM, Proctor DM. 1997. A preliminary assessment of PCB risks to human and ecological health in the lower Passaic River. J Soc Environ Tox Chem 52(2):95–118.