Publication Year

Bylsma LC, Ording AG, Rosenthal A, Öztürk B, Fryzek JP, Arias JM, Röth A, Berentsen S. 2019. Occurrence, thromboembolic risk, and mortality in Danish patients with cold agglutinin disease. Blood Advances 3(20):2980–2985.

Thompson C, Chappell G, Cullen J, Wolf JC, Haws L. Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic Meeting, Durham, NC, August 2019.

Chappell GA, Thompson CM, Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.

Thompson CM. The useful chemistry of perfluorinated compounds: Managing safety. The sticky subject of non-stick: Regulatory science challenges of per- and poly-fluorinated compounds (PFAS). Texas A&M University Interdisciplinary Faculty of Toxicology Training Program, 2019 Annual Regulatory Science Symposium. August 20, 2019.

Clewell RA, Thompson CM, Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301:112–127.

Chappell G, Rager J, Wolf J, Babic M, Leblanc, Ring C, Harris MA, Thompson CM. 2019. Comparison of gene expression responses in the small intestine of mice following exposure to three carcinogens using the S1500+ gene set informs a potential common adverse outcome pathway. Toxicol Pathol (in press).

van de Ligt J, Borghoff SJ, Yoon M, Ferguson LJ, DeMaio W, McClanahan RH. 2019. Nondetectable or minimal detectable residue levels of N-(n-butyl) thiophosphoric triamide in bovine tissues and milk from a 28-d NBPT dosing study. Translat An Sci 3(4).

Cekola P, Henrikson A, Reichert H, Cohen S, Huhmann M, Torres KA. Clinical use and safety of an amino acid-based infant formula in a real world setting. Poster at NASPGHAN, Chicago, IL, October 2019.

Cohen SS, Roger VL, Weston SA, Jiang R, Movva N, Yusuf A, Chamberlain AM. Development of computable phenotypes to identify heart failure patients with preserved ejection fraction. Poster at International Society for Pharmacoepidemiology, Philadelphia, PA, August 2019.

Boice JD Jr, Cohen SS, Mumma MT, Ellis ED. 2019. The Million Person Study, whence it came and why. Int J Radiat Biol 4:1–14, doi: 1080/09553002.2019.1589015.

Chamberlain AM, Cohen SS, Killian JM, Monda KL, Weston SA, Okerson T. 2019. Lipid-lowering prescription patterns in patients with diabetes mellitus or cardiovascular disease. Am J Cardio 124(7):995–1001.

Bylsma LC, Dean R, Lowe K, Sangaré L, Alexander DD, Fryzek JP. 2019. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta‐analysis of patient and study characteristics. Cancer Med 8(12):5800–5809.

Mease K. Managing immunogenicity in the absence of an ADA assay is no monkey business (case study). Presentation at 25^th annual Charles River Biotech Symposium, Carlsbad, CA, September 8–11, 2019.

Lansita J, Weis S. A peek into the black box—Insight from former FDA reviewers on the BLA review process. Presentation at 25^th annual Charles River Biotech Symposium, Carlsbad, CA, September 8–11, 2019.

Nordyke RJ, Reichert H, Bylsma LC, Jackson JJ, Gage SM, Fryzek J, Roy-Chaudhury P, Lithgow T. 2019. Costs attributable to arteriovenous fistula and arteriovenous graft placements in hemodialysis patients with Medicare coverage. Am J Nephrol [Online first, abstract only]: doi: 10.1159/000502507.

Thompson CM, Fitch SE, Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol 39:1267–1282.

Yoon M, Ring C, Van Landingham CB, Suh M, Song G, Antonijevic T, Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380:114695

Fitch S, Goyak K, Green Maia, Grimm F, Wikoff D. 2019. Estrogen-mediated outcomes for alkylphenols via an adverse outcome pathway (AOP) construct. Open Science Framework, August.

Pham LL, Watford S, Friedman KP, Fostel J, Wignall J, Shapiro A. 2019 (in press). Python BMDS: A Python interface library and web application for the canonical EPA dose-response modeling software. Reprod Toxicol (journal pre-proof).

Watford S, Pham LL, Brown J, Wignall J, Shin R, Martin M, Friedman KP. 2019. ToxRefDB 2.0: Improved utility for predictive and retrospective toxicology analyses. Reprod Toxicol 89:145–158. doi: 10.1016/j.reprotox.2019.07.012.

Pham LL, Truong L, Ouedraogo G, Loisel-Joubert S, Martin MT, Friedman KP. 2019. Profiling 58 compounds including cosmetic-relevant chemicals using ToxRefDB and ToxCast. Food Chem Toxicol 132:110718. doi: 10.1016/j.fct.2019.110718.

Fergie J, Gonzales T, Jiang X, Fryzek J, Rizzo CP. Respiratory syncitial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH) among 29-34 weeks gestational age (wGA) preterm infants before and after the 2014 American Academy of Pediatrics (AAP) immunoprophylaxis policy change using the Children’s Hospital Association’s Pediatric Health Information System (PHIS). Poster presentation at IDWeek, Washington, DC, October 2–6, 2019.

Röth A,  Fryzek J, Jiang X, Reichert H, Morales J, Broome CM. Seasonal patterns of thromboembolic events in cold agglutinin disease (CAD) in the United States. Presentation at 81st Annual Meeting of the Japanese Society of Hematology, Tokyo, Japan, October 11–13, 2019.

Röth A, Fryzek J, Jiang X, Reichert H, Morales J, Broome CM. Seasonal patterns of anemia, hemolytic markers, healthcare resource utilization, and thromboembolic events in cold agglutinin disease. Presentation at German Society for Hematology and Medical Oncology, Berlin, Germany, October 11–14, 2019.

Proctor D. Use of the latest science in cancer risk assessment for hexavalent chromium: Is it time to step away from the default regulatory approaches? Invited presentation to the International Union of Toxicology (IUTOX) / International Congress of Toxicology (ICT) meeting, Honolulu, HI, June 17, 2019.

Ring CL, Arnot JA, Bennett DH, Egeghy PP, Fantke P, Huang L, Isaacs KK, Jolliet O, Phillips KA, Price PS, Shin H-M, Westgate JN, Setzer RW, Wambaugh JF. 2019. Consensus modeling of median chemical intake for the U.S. population based on predictions of exposure pathways. Environ Sci Technol 53:719–732.

Insley AL,.Maskrey JR, Hallett LA, Reid RCD, Hynds ES, Winter C, Panko JM. Occupational survey of airborne metal exposures to welders, metalworkers, and bystanders in small fabrication shops. Poster at American Industrial Hygiene Conference and Exhibition, Minneapolis, MN, May 20–24, 2019.

Hopkins B, Cohen SS, Irvin SR, Alberda C. 2019. Achieving protein targets in the ICU using a specialized high-protein enteral formula: A quality improvement project. Nutr Clin Practice, DOI: 10.1002/ncp.10364 – Hopkins_Cohen_NCP_2019.

Unice KM, Weeber MP, Abramson MM, Reid RCD, van Gils JAG, Markus AA, Vethaak AD, Panko JM. 2019. Characterizing export of land-based microplastics to the estuary – Part II: Sensitivity analysis of an integrated geospatial microplastic transport modeling assessment of tire and road wear particles. Sci Tot Environ 646:1650–1659.

Unice KM, Weeber MP, Abramson MM, Reid RCD, van Gils JAG, Markus AA, Vethaak AD, Panko JM. 2019. Characterizing export of land-based microplastics to the estuary — Part I: Application of integrated geospatial microplastic transport models to assess tire and road wear particles in the Seine watershed. Sci Tot Environ 646:1639–1649.

Panko JM, Hitchcock KM, Fuller GW, Green D. 2019. Evaluation of tire wear contribution to PM2.5 in urban environments. Atmosphere 10(2):99, https://doi.org/10.3390/atmos10020099.

Insley AL, Maskrey JR, Hallett LA, Reid RCD, Hynds ES, Winter C, Panko JM. 2019. Occupational survey of airborne metal exposures to welders, metalworkers, and bystanders in small fabrication shops. J Occup Environ Hyg 16:6:410–421, DOI: 10.1080/15459624.2019.1603389.

Thompson CM, Fitch SE, Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol, open access.

Wikoff D, Haws L, Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol, doi: 10.1002/jat.3814, open access.

Wikoff D, Erranguntla N, Lewis J, Foreman J. A fit-for-purpose framework for use of systematic methods in risk assessment. Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Urban J, Wikoff D, Haws L. Three-tiered approach to integrating evidence streams assessing gestational trichloroethylene exposure and congenital heart defects (TCE-CHD). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine. Washington, DC, June 2019.

Borghoff S, Fitch S, Britt J, Franke K, Wikoff D. Application of the EFSA/ECHA endocrine disruption guidance as a framework for evidence integration in a weight-of-evidence (WoE) analysis for oxybenzone (BP-3). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Kreider ML, Hynds ES, Panko JM. Evaluation of tire and road wear particles (TRWP) in air in Delhi, India. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 10–14, 2019.

Honda GS, Pearce RG, Pham LL, Setzer RW, Wetmore BA, Sipes NS, Gilbert J, Franz B, Thomas RS, Wambaugh JF. 2019. Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions. PLoS ONE 14(5):e0217564.

Pham LL, Sheffield T, Pradeep P, Brown J, Haggard D, Wambaugh J, Judson R, Friedman KP. 2019. Estimating uncertainty in the context of new approach methodologies for potential use in chemical safety evaluation. Curr Opin Toxicol 15:40-47.

Chamberlain AM, Cohen SS, Weston SA, Fox KM, Xiang P Killian JM Qian Y. 2019. Relation of cardiovascular events and deaths to low-density lipoprotein cholesterol level among statin-treated patients with atherosclerotic cardiovascular disease. Am J Cardiol 123(11):1739-1744.

Storm HM, Shepard J, Czerkies LM, Kineman B, Cohen SS, Reichert H, Carvalho R. 2019. 2’-Fucosyllactose is well tolerated in a 100% whey, partially hydrolyzed infant formula with Bifidobacterium lactis: A randomized controlled trial. Global Pediat Health 6:1–10. DOI: 10.1177/2333794X19833995.

Klosterbuer A, Neutel JM, Cohen SS, Periman S. Plasma glucose and insulin response to high protein oral nutritional supplements in adults with type 2 diabetes mellitus. Poster at ASPEN 2019 Nutrition Science & Practice Conference, March 2019, Phoenix, AZ.

Wikoff D. Rigor and resources for systematic reviews in toxicology: Case study applications in food safety, consumer product safety, and environmental health risk assessment. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Gentry R, Greene T, Granzen A, Thompson CM. Formaldehyde and leukemia: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Urban J, Wikoff D, Suh M, Britt J, Harvey S, Chappell G, Haws L. Comparison of NTP OHAT and US EPA TSCA study quality criteria: Trichloroethylene (TCE) and congenital heart defects (CHDs) as a case study. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

McIntyre B, Zorilla L, Borghoff, S, Foster P. Assessment of avobenzone, ensulizole, homosalate, and padimate-O in endocrine disruptor screening panel studies. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Thompson CM, Gentry R. An updated mode-of-action analysis for formaldehyde-induced nasal tumors in rodents: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Borghoff SJ, Fitch S, Huggett, Wikoff D. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA). 2019. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Saili KS, Zurlinden TH, Antonijevic T, Shah I, Deisenroth C, Knudsen TB. Endodermal differentiation trajectories diverge with increasing all-trans retinoic acid (ATRA) exposure. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Yoon M, Ring C, Van Landingham CV, Gentry PR, Taylor MD, Keene AM, Clewell HJ. Assessing early life drinking water exposures to manganese (Mn). Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C. Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Henderson RG, Doepker C, Lopez JG. Safety evaluation of L-theanine administered via hard chew to dogs. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, Ring C, Proctor D. 2019. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Crit Rev Toxicol [ePub ahead of print]: doi: 10.1080/10408444.2019.1578730.

Fitch S, van de Ligt J, Payne L, Doepker C, Kleinman R, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2019. Systematic map protocol: A systematic map of the use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS). Open Science Framework.

Suh M, Casteel S, Dunsmore M, Ring C, Verwiel A, Proctor DM. 2019. Bioaccessibility and relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Sci Tot Environ 660:677–689.