Publication Topic

Suzuki T, Campos B, Fassbender C, Grassi G, Hodges J, Kennedy S, et al. Advancing animal-free environmental safety assessments: Development and application of an integrated next generation risk assessment (NGRA) framework. Presentation 5.09.T-02, SETAC North America 47^th Annual Meeting, Montreal, Canada, November 2026.

Nagyal M, Kopanska K, Rovida C, Antignac E, Barton-Maclaren T, Congreave I, Escher SE,…, Patlewicz G, et al. From thresholds to odds: AI-enhanced applications of the threshold of toxicological concern (TTC) in modern risk assessment. Oral Session 3, Poster OR-12, American Society for Cellular and Computational Toxicology (ASCCT) 15^th Annual Meeting, Durham, NC, October 28, 2026.

Covington T, Borghoff SJ, Sims JL, Kamel A, Markey K, Wetmore BA, Lynn SG. Use of an in silico mass balance model to predict chemical suitability for screening chemicals in a high-throughput assay platform for potential endocrine activity. Poster 3, Poster Session II, American Society for Cellular and Computational Toxicology (ASCCT) 15^th Annual Meeting, Durham, NC, October 28, 2026

Wikoff D, Wages PA. Where science meets reality: The role of real-world evidence (RWE) in modern personal care safety assessment. 2026 Personal Care Products Council (PCPC) Science Symposium & Expo, Arlington, VA, September 17, 2026.

Kennedy S. Next-generation environmental risk assessment for cosmetics ingredients—Framework and case study. 2026 Personal Care Products Council (PCPC) Science Symposium & Expo, Arlington, VA, September 16, 2026.

Bearth A, Kopainsky B, Jones LB, Vist GE, Husoy T, Svendsen C, Whaley P,…, Wikoff D, et al. 2026. Modelling the regulatory toxicology system to promote the effective use of new approach methodologies: A system thinking approach. NAM J 2(Jul 24):100120; doi: 10.1016/j.namjnl.2026.100120. PMID: 42569723

Mathisen GH, Whaley P, Kopainsky B, Ames HM, Hoffmann S, Husoy T, Jones L,…, Wikoff D, et al. 2026. Preparing for CHANGE: How systems thinking supports an effective transition from animal studies to NAMS. NAM J 2(July 20):100118; doi: 10.1016/j.namjnl.2026.100118. PMID: 42564567.

Haws L (Moderator), Maxwell G (Speaker), Kleinstreuer N, Lowit A, Harrill J (Panelists). Next generation risk assessment (NGRA): Emerging best practice & opportunities for regulatory use. Society of Toxicology Risk Assessment Specialty Section (RASS) Risk Assessment Syllabus Webinar, June 17, 2026.

Kennedy SB, Heintz MM, Brown L, Fender CL, Hecker M, Hughes SA, Naile J, DeLeo P. Defining the domain of applicability: A case study to increase confidence in toxicogenomic tools for ecological risk assessment. Poster 1.03.P-Tu032, SETAC Europe 36^th Annual Meeting, Maastricht, The Netherlands, May 19, 2026.

Wigh A, Campos B, de Croze N, Roush K, Suzuki T, Brown L, Kennedy SB, Hecker M, et al. Chronic fish toxicity case studies toward a best practice guidance document. Poster 1.09P-Mo042, SETAC Europe 36^th Annual Meeting, Maastricht, The Netherlands, May 18, 2026.

Fitch S, Lozy F, Mitchell C, Patlewicz G, Wood A. Use of new approach methodologies in the safety assessment of dietary supplements—Parts one and two. Webinar series, Council for Responsible Nutrition (CRN), Washington, DC, May 2026.

Mahony C, Bartlett A, Fitzpatrick S, Galli C, Hunt P, Inselman A, Jimenez J,…, Rogers J, et al. 2026. A screening strategy for identifying the developmental and reproductive toxicity potential of botanicals. 64(1):639-557; doi: 10.1080/13880209.2026.2659421. PMID: 42048162.

Shobair M, Allen D, Ballone I, Brull M, Burbank M, Choksi N, Fitch S, Irizar A, et al. A machine-learning approach for the development of a knowledgebase to identify systemic toxicity mechanistic targets and evaluate biological space coverage. Abstract 5161, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Patlewicz G, Judson, Paul Friedman K, Wetmore BA, DeVito MJ, Harrill JA, Carstens KE, Houck KA, et al. 2026. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs). J Toxicol Environ Health B 29(1):1-69; doi: 10.1080/10937404.2025.2521615. PMID: 40619890.

Wheeler M, Wikoff D, Vincent M. Annealed Bayesian bias assessment in epidemiological studies. Session M2-H, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Hoffman S, Wikoff D, Brown L, Wheeler M. Advancing quantitative uncertainty assessment in next generation risk assessment. Session T2-A, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Fender CL, Garcia-Jaramillo M, Jackson ME, Truong L, Tanguay RL, Schindler J, Lee K, Bright PW. Start to finish: Discovery, quantification and toxicity assessment of emerging contaminants in tap drinking water using mixed and new approach methods. Abstract 4.16.T-02, SETAC North America 46^th Annual Meeting, Portland, OR, November 2025.

Patlewicz G, Charest N, Ross A, Bledsoe HC, Vidal J, Faramarzi S, Hagan B, Shah I. 2025. Building a compendium of expert driven read-across cases to facilitate an analysis of the contribution that different similarity contexts play in read-across performance. Comput Toxicol 35(Sept):100366; doi: 10.1016/j.comtox.2025.100366.

Nyffeler J, Harris FR, Willis C, Byrd G, Blackwell B, Escher BI, Kasparek A, Nichols J,…, Patlewicz G, et al. 2025. A combination of high-throughput in vitro and in silico new approach methods (NAMs) for ecotoxicology hazard assessment for fish. Environ Toxicol Chem 44(9):2599-2621; doi: 10.1093/etojnl/vgae083. PMID: 39937625.

Moyer HL, Vergara L, Stephan C, Sakolish C, Lin HC, Chiu WA, Villenave R, Hewitt P, et al. 2025. Human small intestinal tissue models to assess barrier permeability: Comparative analysis of caco-2 cells, jejunal and duodenal enteroid-derived cells, and EpiIntestinal^TM tissues in membrane-based cultures with and without flow. Bioengineering (Basel) 12(8):809; doi: 10.3390/bioengineering12080809. PMID: 40868322.