Publication Topic

Haws L (Moderator), Maxwell G (Speaker), Kleinstreuer N, Lowit A, Harrill J (Panelists). Next generation risk assessment (NGRA): Emerging best practice & opportunities for regulatory use. Society of Toxicology Risk Assessment Specialty Section (RASS) Risk Assessment Syllabus Webinar, June 17, 2026.

Kennedy SB, Heintz MM, Brown L, Fender CL, Hecker M, Hughes SA, Naile J, DeLeo P. Defining the domain of applicability: A case study to increase confidence in toxicogenomic tools for ecological risk assessment. Poster 1.03.P-Tu032, SETAC Europe 36^th Annual Meeting, Maastricht, The Netherlands, May 19, 2026.

Wigh A, Campos B, de Croze N, Roush K, Suzuki T, Brown L, Kennedy SB, Hecker M, et al. Chronic fish toxicity case studies toward a best practice guidance document. Poster 1.09P-Mo042, SETAC Europe 36^th Annual Meeting, Maastricht, The Netherlands, May 18, 2026.

Fitch S, Lozy F, Mitchell C, Patlewicz G, Wood A. Use of new approach methodologies in the safety assessment of dietary supplements—Parts one and two. Webinar series, Council for Responsible Nutrition (CRN), Washington, DC, May 2026.

Mahony C, Bartlett A, Fitzpatrick S, Galli C, Hunt P, Inselman A, Jimenez J,…, Rogers J, et al. 2026. A screening strategy for identifying the developmental and reproductive toxicity potential of botanicals. 64(1):639-557; doi: 10.1080/13880209.2026.2659421. PMID: 42048162.

Shobair M, Allen D, Ballone I, Brull M, Burbank M, Choksi N, Fitch S, Irizar A, et al. A machine-learning approach for the development of a knowledgebase to identify systemic toxicity mechanistic targets and evaluate biological space coverage. Abstract 5161, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Patlewicz G, Judson, Paul Friedman K, Wetmore BA, DeVito MJ, Harrill JA, Carstens KE, Houck KA, et al. 2026. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs). J Toxicol Environ Health B 29(1):1-69; doi: 10.1080/10937404.2025.2521615. PMID: 40619890.

Wheeler M, Wikoff D, Vincent M. Annealed Bayesian bias assessment in epidemiological studies. Session M2-H, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Hoffman S, Wikoff D, Brown L, Wheeler M. Advancing quantitative uncertainty assessment in next generation risk assessment. Session T2-A, Society for Risk Analysis (SRA) Annual Meeting, Washington, DC, December 2025.

Fender CL, Garcia-Jaramillo M, Jackson ME, Truong L, Tanguay RL, Schindler J, Lee K, Bright PW. Start to finish: Discovery, quantification and toxicity assessment of emerging contaminants in tap drinking water using mixed and new approach methods. Abstract 4.16.T-02, SETAC North America 46^th Annual Meeting, Portland, OR, November 2025.

Patlewicz G, Charest N, Ross A, Bledsoe HC, Vidal J, Faramarzi S, Hagan B, Shah I. 2025. Building a compendium of expert driven read-across cases to facilitate an analysis of the contribution that different similarity contexts play in read-across performance. Comput Toxicol 35(Sept):100366; doi: 10.1016/j.comtox.2025.100366.

Nyffeler J, Harris FR, Willis C, Byrd G, Blackwell B, Escher BI, Kasparek A, Nichols J,…, Patlewicz G, et al. 2025. A combination of high-throughput in vitro and in silico new approach methods (NAMs) for ecotoxicology hazard assessment for fish. Environ Toxicol Chem 44(9):2599-2621; doi: 10.1093/etojnl/vgae083. PMID: 39937625.

Moyer HL, Vergara L, Stephan C, Sakolish C, Lin HC, Chiu WA, Villenave R, Hewitt P, et al. 2025. Human small intestinal tissue models to assess barrier permeability: Comparative analysis of caco-2 cells, jejunal and duodenal enteroid-derived cells, and EpiIntestinal^TM tissues in membrane-based cultures with and without flow. Bioengineering (Basel) 12(8):809; doi: 10.3390/bioengineering12080809. PMID: 40868322.

Leary A, Shah I, Patlewicz G. 2025. An exploration of the use of hybrid fingerprints in Generalized Read-Across and their impact on predictive performance for selected in vivo toxicity outcomes. Comput Toxicol 34(June):100349; doi: 10.1016/j.comtox.2025.100349.

Diemar MG, Giusti A, Michel-Caillet C, Leme DM, Wikoff D, Bloch D, Sass J, Beekmann K, et al. 2025. How to organize a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024. Arch Toxicol 99(7):3057-3063; doi: 10.1007/s00204-025-04064-6. PMID: 40372420.

Wikoff D. An introduction to evidence integration. Workshop Session, Abstract 1333, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Hanser T, Ahlberg E, Amberg A, Anger LT, Barber C, Brennan RJ, Brigo A,…, Greene N, et al. 2025. Data-driven federated learning in drug discovery with knowledge distillation. Nat Mach Intell 7(Mar):423–436; doi: 10.1038/s42256-025-00991-2.

Schaefer H. An introduction to evidence integration. Abstract 1333, Society of Toxicology 64th Annual Meeting, Orlando, FL, 2025

Patlewicz G, Williams AJ, Adams M, Shah I, Paul-Friedman K. 2025. A cheminformatics workflow to select representative TSCA chemicals for New Approach Methodology (NAM) screening. Chem Res Toxicol 38(1):129-144; doi: 10.1021/acs.chemrestox.4c00367. PMID: 39655894.

Haber LT, Bradley MA, Buerger AN, Behrsing H, Burla S, Clapp PW, et al. 2024. New approach methodologies (NAMs) for the in vitro assessment of cleaning products for respiratory irritation: Workshop report. Front Toxicol 6:1431790; doi: 10.3389/ftox.2024.1431790. PMID: 39439531.