This talk describes a project steered by the International Collaboration on Cosmetics Safety (ICCS) that aims to develop a next generation environmental risk assessment (NGeRA) framework that considers both human and environmental evidence and demonstrate proof of concept by applying the framework to 2-3 cosmetic ingredients as case studies. The approach to develop the NGeRA framework will be discussed, as well as findings for the case study ingredients. The outcome of the case studies will demonstrate how to use the proposed NGeRA framework with cosmetics ingredients, how an environmental assessment can be conducted in the absence of experimental animal data (i.e., demonstrate how to use non-animal/new approach methodologies (NAMs) in NGeRA), and provide a comparison to safety assessments completed with “traditional” hazard data.