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2026 (24 POSTS)

Killius A, Wheeler M, Covell L, Price S, Finley B. 2026. Derivation of provisional chronic oral toxicity values (PCOTV) for novel short-chain PFAS congeners. J Appl Toxicol 46(10):3415-3423; doi: 10.1002/jat.70156. PMID: 41814952.

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Wikoff D, Wages PA. Where science meets reality: The role of real-world evidence (RWE) in modern personal care safety assessment. 2026 Personal Care Products Council (PCPC) Science Symposium & Expo, Arlington, VA, September 17, 2026.

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Kennedy S. Next-generation environmental risk assessment for cosmetics ingredients—Framework and case study. 2026 Personal Care Products Council (PCPC) Science Symposium & Expo, Arlington, VA, September 16, 2026.

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Bearth A, Kopainsky B, Jones LB, Vist GE, Husoy T, Svendsen C, Whaley P,…, Wikoff D, et al. 2026. Modelling the regulatory toxicology system to promote the effective use of new approach methodologies: A system thinking approach. NAM J 2(Jul 24):100120; doi: 10.1016/j.namjnl.2026.100120. PMID: 42569723

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Kirman CR, Lipscomb JC, Rogers J, Schoeny RS, Seed JG, Sonawane BR, Hays SM. 2026. Evaluation of the modes of action for key noncancer effects of 1,3-Butadiene: Input from an independent expert panel to support derivation of data-derived extrapolation factors. Crit Rev Toxicol 56(4):252-278; doi: 10.1080/10408444.2026.2661191. PMID: 42261678.

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Buerger AN, Thompson CM, Heintz MM, Maberti S, Palermo CM, Haws LC. 2026. Application of quantitative and qualitative uncertainty assessment risk management decision-making: A case study with diisononyl phthalate. Food Chem Toxicol 214(Aug):116110; doi: 10.1016/j.fct.2026116110. PMID: 42035978.

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Torres C, Kramer A, Racz L, Vivanco S, Panko J. Anticipating number of days that exceed OSHA proposed heat triggers. Abstract 1501, Poster Session 3, AIHA Connect 2026, New Orleans, LA, June 3, 2026.

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Kramer M, Torres CV. Feasibility assessment of EPA’s OEVs/ECELs. Research Roundup Presentation C1b, AIHA Connect 2026, New Orleans, LA, June 1, 2026.

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Haws L (Moderator), Maxwell G (Speaker), Kleinstreuer N, Lowit A, Harrill J (Panelists). Next generation risk assessment (NGRA): Emerging best practice & opportunities for regulatory use. Society of Toxicology Risk Assessment Specialty Section (RASS) Risk Assessment Syllabus Webinar, June 17, 2026.

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Bond G, Becker RA, Rish W, Ryman JP, Verwiel AH. 2026. Cumulative impact assessment within vulnerable communities: Challenges, opportunities and path forward. J Toxicol Regul Pol 2(1):1-19; doi: 10.69982/JTRP-25-0012.

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Kennedy SB, Heintz MM, Brown L, Fender CL, Hecker M, Hughes SA, Naile J, DeLeo P. Defining the domain of applicability: A case study to increase confidence in toxicogenomic tools for ecological risk assessment. Poster 1.03.P-Tu032, SETAC Europe 36th Annual Meeting, Maastricht, The Netherlands, May 19, 2026.

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Thompson CM, Heintz MM, Rogers SI, Vincent MJ, Haws LC. 2026. Integration of mechanistic and repeat dose toxicity data in the derivation of an oral reference dose for HFPO-DA. Toxicol Sci 209(5):kfag045; doi: 10.1093/toxsci/kfag045. PMID: 41968070.

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Doepker C, Franzen A, Brorby G, Brown L, Choksi N, East A, Wikoff D. 2026. Smoke flavoring—A case study demonstrating the value of using benefit-risk analysis for foods (BRAFO) to provide transparency for risk management decisions. Regul Toxicol Pharmacol 167(May):106033; doi: 10.1016/j.yrtph.2026.106033. PMID: 41577161.

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Lea IA, Buerger AN, Vincent MJ,…, Choksi NY, Schaefer H, Britt J, Fitch S, Haws L, Borghoff SJ. 2026. Evaluating the potential carcinogenic hazard of diisononyl phthalate in humans via systematic integration of human, animal cancer studies, and mechanistic data. Curr Res Toxicol 10(Apr 30):100295; doi: 10.1016/j.crtox.2026.100295.

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Massarsky A, Evans VJB, Fung ES, Yang LGL, Rogers KL, Buerger AN, Maier A, Reichard JF. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions—Part II: Framework application in four case studies. Crit Rev Toxicol; doi: 10.1080/10408444.2026.2633422. Online ahead of print April 16. PMID: 41988975.

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Massarsky A, Evans VJB, Fung ES, Yang LGL, Rogers KL, Buerger AN, Maier A, Reichard JF. A framework for assessing the safety of degraded pharmaceuticals that will be required for long-duration space missions—Part I: Framework development. Crit Rev Toxicol; doi: 10.1080/10408444.2025.2533943. Online ahead of print April 9. PMID: 4195218.

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Vincent M, Wheeler M, Schaefer H, Rhoden J, Fitch S, Wikoff D. Quantitative bias assessment to facilitate assessment of (un)certainty in observational data evaluating acetaminophen use and liver cancer. Abstract 4279, Society of Toxicology 65th Annual Meeting, San Diego, CA, March 2026.

Shobair M, Allen D, Ballone I, Brull M, Burbank M, Choksi N, Fitch S, Irizar A, et al. A machine-learning approach for the development of a knowledgebase to identify systemic toxicity mechanistic targets and evaluate biological space coverage. Abstract 5161, Society of Toxicology 65th Annual Meeting, San Diego, CA, March 2026.

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Patlewicz G, Mihalchik A, Thompson CM, East A, Borghoff S. Investigating the feasibility of deriving a new environmentally relevant Thresholds of Toxicological Concern (TTCs) from estimated human equivalent benchmark dose (eBMDHED) values. Abstract 4013, Society of Toxicology 65th Annual Meeting, San Diego, CA, March 2026.

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Faske JB, Gong B, LeBlanc DP, Funk J, Zhou G, Kehm S, White PA, Robison T, et al. 2026. Expansion of preexisting cancer driver mutant clones is induced by the genotoxic carcinogen benzo[b]fluoranthene in MutaMouse lung. Toxicol Sci 209(3):kfag030; doi: 10.1093/toxsci/kfag030. PMID: 41859812.

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