Publication Topic

Catalano S, Choksi N, Corvaro M, Kolle S, Stinchombe S, Latorre A, et al. Reducing animal use for eye irritation testing of agrochemicals in Brazil. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Allen DG, Rooney J, To K, Choksi N, Ceger P, Daniel A, et al. Variability in reference test method data and the impact on NAM evaluations. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Robison TW, Heflich RH, Manjanatha MG, Elespuru R, Atrakchi A, Mei N, Ding W. 2021. Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug- related metabolite, or drug-related impurity. Mutat Res Gen Toxicol Environ Mutagen 868-869(Aug-Sept):503386; doi: 10.1016/j.mrgentox.2021.503386. PMID: 34454692.

Wang Y, Mittelstaedt RA, Wynne R, Chen Y, Cao X, Muskhelishvili L, Davis K, Robison TW, et al. 2021. Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by duplex sequencing. Environ Mol Mutagen 62(5):306-318; doi: 10.1002/em22444. PMID: 34050964.

Rooney JP, Choksi NY, Ceger P, Daniel AB, Truax J, Allen D, Kleinstreuer N 2021. Analysis of variability in in vivo rabbit skin irritation assay results. Regul Toxicol Pharmacol 122(June):104920; doi: 10.1016/j.yrtph.2021.104920. PMID: 33757807.

Choksi NY, Daniel AB, Allen DG, Clippinger AJ, Kleinstreuer NC. 2021. Prospective and retrospective evaluation of the eye irritation potential of agrochemical formulations. Research Triangle Park, NC: National Toxicology Program. NICEATM Report 01.

O’Neil HC, Vincent MJ, Han AA, Brown SE, Hazell AM, Krieder ML, Madl AM. Hazard and risk banding framework for prioritization and bridging of e-liquids for toxicity testing. Poster presented at Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Rooney JP, Choksi N, Ceger P, Daniel AB, Truax J, Allen DG, Kleinstreuer NC. Variability in the rabbit skin irritation assay. Poster presented at Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Eskes C, Corsini E, Hanley V, Karadjova I, Kopp-Schneider A, Suh M, Alves P, Clewell R, et al. 2020. ESAC opinion on the scientific validity of the bioelution test method. In: Viegas Barroso J (ed), EUR 30281 EN. Publications Office of the European Union, Luxembourg, ISBN 978-92-76-20004-8 (online), doi:10.2760/023005 (online), JRC121143.

Choksi N, Lebrun S, Nguyen M, Daniel A, DeGeorge G, Willoughby J, et al. 2020. Validation of the OptiSafe eye irritation test. Cutan Ocul Toxicol 39(3):180–192; doi: 10.1080/15569527.2020.1787431. PMID: 32586141.

Choksi N, Clippinger AJ, Gehen S, Corvaro M, Kolle SN, Bentley K, et al. Developing a defined approach for eye irritation testing. Poster presented at Society of Toxicology 59th Annual Meeting, Virtual, March 2020.

Choksi NY, Truax J, Layton A, Matheson J, Mattie D, Varney T, et al. 2019. United States regulatory requirements for skin and eye irritation testing. Cutan Ocul Toxicol 38(2):141–155; doi: 10.1080/15569527.2018.1540494. PMID: 30418044.

Sacks NC, Sharma A, Cyr PL, Stong L, Dahdal DN. Real-world evidence comparison of colorectal cancer screening outcomes with different colorectal cancer preparation agents in adults 65 years and older. Digestive Disease Week Annual Meeting, San Diego, May 2019.

Patlewicz G, Richard AM, Williams AJ, Grulke CM, Sams R, Lambert J, Noyes P, DeVito MJ, et al. 2019. A chemical category-based prioritization approach for selecting 75 per- and polyfluoroalkyl substances (PFAS) for tiered toxicity and toxicokinetic testing. Environ Health Perspect 127(1):14501; doi: 10.1289/EHP4555. PMID: 30632786.

Sacks NC, Sharma A, Cyr PL, Bertiger G, Dahdal DN, Brogadir S. 2018. Real-world comparison of the effectiveness and safety of different bowel preparation agents. Clin Exp Gastroenterol 11(Aug 16):289–299; doi: 10.2147/CEG.S171861. PMID: 30555250.

Klaren WD, Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342; doi: 10.1089/adt.2018.86. PMID: 30070899.

Sacks NC, Sharma A, Cyr PL, Bertiger G, Dahdal DN, Brogadir S. Real-world evidence comparison of the efficacy and safety of different bowel preparation agents in a high-risk population. Abstract Su1920, 2018 Digestive Disease Week (DDW) Conference. Gastroenterol 154(6) S632-S633; doi: 10.1016/S0016-5085(18)32266-2. Washington, DC, June 2018.

Iwata Y, Klaren WD, Lebakken CS, Grimm FA, Rusyn I. 2017. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay Drug Dev Technol 15(6):267–279; doi: 10.1089/adt.2017.786. PMID: 28771372.

Sheppard A, Baker E, Bermudez D, Blattner J, Boyd K, O’Neal S, Rahim T, Whittle E. Implementing an alternate testing strategy for assessing skin irritation. Abstract #2734, Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.

Sheppard A, Baker E, Bermudez D, Blattner J, Boyd K, O’Neal S, Rahim T, Whittle E. Use of alternative methods to assess skin irritation of chemical mixtures. World Congress for Alternatives to Animal Testing, Seattle, WA, 2017.