Publication Year

Proctor DM, Suh M, Mittal L, Hirsch S, Salgado RV, Bartlett C, Van Landingham C, Rohr A, Crump K. 2015. Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. J Expo Sci Environ Epidemiol 26(2):224-231. doi: 10.1038/jes.2015.77.

Hester S, Eastmond DA, Bhat VS. 2015. Developing toxicogenomics as a research tool by applying benchmark dose-response modeling to inform chemical mode of action and tumorigenic potency. Invited Contribution, Special Issue on Toxicogenomics: The emergence of a new research and regulatory paradigm. Inter J Biotechnol 14:28-46.

Lansita JA, Burke JM, Apgar JF, Mounho-Zamora B. 2015. An introduction to the regulatory and nonclinical aspects of the nonclinical development of antibody drug conjugates. Pharmceut Res 32(11):3584-3592. DOI 10.1007/s11095-015-1742-y

Hughes BJ, LeBaron MJ, Thomas J, Kan HL, Lynch AM, Borghoff SJ, Green S, Mensing T, Sarang SS, Smulders CJGM. 2015. Activation of CAR and PXR nuclear receptors in the liver of MIBK-exposed mice. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, 2015. San Diego, CA.

Kirman CR, Proctor DM, Suh M, Hays S. 2015. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Suh M, Mittal L, Hirsch S, Valdes R, Bartlett C, Rohr A, Proctor D. 2015. Lung cancer risk in chromate production workers exposed to hexavalent chromium. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Britt J, James R. 2015. Welding and occupational exposure to manganese fumes and Parkinson’s disease:  An evidence-based causation analysis. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Mounho-Zamora B, Weissman I, Volkmer J, Willingham S, Prohaska S, Howard M, Jie L, Majeti R.2015.  Nonclinical safety assessment of a monoclonal antibody against CD47. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Doepker C, Brorby G. 2015. The role of the toxicologist in required food safety plans:  A case study of ochratoxin A (OTA) in coffee. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Proctor D, Suh M, Thompson C, Hixon, G. 2015. Inhalation cancer risk assessment of titanium dioxide. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Urban JD, Thompson CM, Plunkett LM, Perry CS, Haws LC. 2015. A state of the science copper reference dose for soil remediation. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Harris MA, Thompson CM, Proctor DM, Suh M, Wolf JC, Seiter JM, Chappell MA, Haws LC. 2015. Analysis of duodenal crypt health following exposure to Cr(VI) in drinking water. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Thompson CM, Young RR, Suh M, Dinesdurage H, Elbekai R, Harris MA, Rohr AC, Proctor DM. 2015. Hexavalent chromium does not induce mutations in the oral mucosa of transgenic Big Blue® rats following drinking water exposures at a carcinogenic dose. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Thompson CM, Suh M, Hixon G, Bichteler A. 2015. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Borghoff SJ, Wikoff D, White MC, Thompson C, Haws LC. 2015. Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Wikoff D, White MC, Borghoff SJ, Haws LC. 2015. Evaluation of tetrabromobisphenol A (TBBPA)-induced endocrine-related target gene activity using high-throughput screening data from ToxCast. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

Brorby G, Suh M, Bichteler A, Proctor D. Use of cluster analysis and homogeneity testing to characterize distributions of exposures among beryllium workers: Tools for developing occupational exposure limits from quantitative risk assessment.  Presented at International Society of Exposure Science 25th Annual Meeting, Henderson, NV, October 18-22, 2015.

Thompson CM, Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M, Proctor DM, Bichteler A, Haws LC, Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66.

Mason AM, Spencer PJ, Panko JM. A pilot project reveals prominent hazard screening tools fall short on performance expectations. Poster at the 54th Annual Meeting and Society of Toxicology (SOT) Meeting, San Diego, CA, March 22–26, 2015.

Panko JM, Hitchcock KM, Fung M, Spencer PJ, Kingsbury T, Mason AM. A comparative evaluation of seven hazard screening tools. Poster at 25th Annual Meeting of NorCal SETAC, Sacramento, CA, April 29–30, 2015.

Panko JM, Hitchcock KM. From critical reviews of hazard assessment tools to building a product evaluation framework: Can we bridge the gaps with a super tool? Presentation at the American Industrial Hygiene Conference & Expo (AIHce), Salt Lake City, UT, May 30 – June 4, 2015.

Unice KM, Bare JL, Kreider ML, Panko JM. Evaluation of leachate from tire and road wear particles (TRWP) upflow percolation column tests. Poster at Society of Environmental Toxicology and Chemistry, 36th Annual Meeting, Salt Lake City, UT, November 1–5, 2015.

Gauthier AM, Fung M, Panko J, Kingsbury T, Perez AL, Hitchcock K, Ferracini T, Sahmel J, Banducci A, Jacobsen M, Abelmann A, Shay E. 2015. Chemical assessment state of the science: Evaluation of 32 decision-support tools used to screen and prioritize chemicals. Integr Environ Assess Manag 11(2):242–255.

Kreider ML, Cyrs WD, Tosiano MA, Panko JM. 2015. Evaluation of quantitative exposure assessment method for nanomaterials in mixed dust environments: Application in tire manufacturing facilities. Ann Occup Hyg
59(9):1122–1134.

Thompson CM, Young RR, Suh M, Dinesdurage HR, Elbekai RH, Harris MA, Rohr AC, Proctor DM. 2015. Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats. Environ Mol Mutagen 56:621-628.

James RC, Roberts SM, Williams PL. 2015. General principles of toxicology. In: Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York.

Young RR, Thompson CM, Dinesdurage HR, Elbekai RH, Suh M, Rohr AC, Proctor DM. 2015. A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats. Environ Mol Mutagen 56:629-636.

James RC, Roberts SM. 2015. Hepatoxicity: Toxic effects on the liver. In: Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York, NY.

Stuchal LD, James RC, Roberts SM. 2015. Human health risk assessment. In: Principles Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York, NY.

Borghoff SJ, Poet TS, Green S, Davis J, Hughes B, Mensing T, Sarang SS, Lynch AM, Hard GC.  2015. Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding. Toxicology 333(2015):1-13.

Lansita JA, Mounho-Zamora B. 2015. The development of therapeutic monoclonal antibodies:  Overview of the nonclinical safety assessment. Curr Pain Headache Rep 19(3):472.

Britt JK. 2015. Properties and effects of pesticides. In: Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York.

Urban JD, Carakostas MC, Taylor SL. 2015. Steviol glycoside safety: Are highly purified steviol glycoside sweeteners food allergens? Food Chem Toxicol 75: 71-78.

Thompson CM, Seiter J, Chappell MA, Tappero RV, Proctor DM, Suh M, Wolf JC, Haws LC, Vitale R, Mittal L, Kirman CR, Hays SM, Harris MA. 2015. Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water. Toxicol Sci 143(1): 16-25.

Ramani T, Auletta CS, Weinstock D, Mounho-Zamora B, Ryan PC, Salcedo TW, Bannish G. 2015. Cytokines: The good, the bad, and the deadly. Int J Toxicol 34(4):355–365, DOI 10.1177/1091581815584918.