Publications

Mihalchik AL, Roberts A, LaCombe J, Lloyd M, Doepker C, Eapen A. 2026. Evaluation of the safety and potential genotoxicity of a high-purity mogroside ingredient containing siamenoside I produced from a modified strain of Yarrowia lipolytica. Toxicol Rep 17(Dec):102297; doi: 10.1016/j.toxrep.2026.102297. PMID: 42388455.

Pochron ST, Ye X, Maroli AS, Venkatesan AK, Sasoun S, Gaylor TJ, Girgis M, Jacobellis MA, et al. 2026. Recreational microplastics as emerging pollutants: Effects of crumb rubber leachate across ecosystems. Chemosphere 410(Sept):145034; doi: 10.1016/j.chemosphere.2026.145034. PMID: 42447661.

Summan M, Doepker CL, Brorby GP. 2026. Safety evaluation of an aqueous root and leaf extract of Ashwagandha (Withania somnifera). Phytother Res 40(8):5030-5047; doi: 10.1002/ptr.70314. PMID: 41987003.

Frankenfeld CL, Movva N, Hooda N, Gauthier J, Reichert H, Doepker C. 2026. Analysis of National Health and Nutrition Survey (NHANES): Nutrient, food, and beverage intake of glucagon-like peptide-1 receptor agonist users with type 2 diabetes, 2007-2020. J Nutr 156(8):101685; doi: 10.1016/j.tjnut.2026.101685. PMID: 42331063.

Bearth A, Kopainsky B, Jones LB, Vist GE, Husoy T, Svendsen C, Whaley P,…, Wikoff D, et al. 2026. Modelling the regulatory toxicology system to promote the effective use of new approach methodologies: A system thinking approach. NAM J 2(Jul 24):100120; doi: 10.1016/j.namjnl.2026.100120. PMID: 42569723

Mathisen GH, Whaley P, Kopainsky B, Ames HM, Hoffmann S, Husoy T, Jones L,…, Wikoff D, et al. 2026. Preparing for CHANGE: How systems thinking supports an effective transition from animal studies to NAMS. NAM J 2(July 20):100118; doi: 10.1016/j.namjnl.2026.100118. PMID: 42564567.

Bright PW, Jackson ME, Fender CL, Lee K, Haggerty C, Schindler J, Truong L, Tanguay RL, Garcia-Jaramillo M. 2026. Integrated chemical and toxicity screening of tap drinking water across Western Oregon using suspect and nontarget screening. Environ Sci Technol 60(25):17706-17717; doi: 10.1021/acs.est.6c01661. PMID: 42304736.

Kirman CR, Lipscomb JC, Rogers J, Schoeny RS, Seed JG, Sonawane BR, Hays SM. 2026. Evaluation of the modes of action for key noncancer effects of 1,3-Butadiene: Input from an independent expert panel to support derivation of data-derived extrapolation factors. Crit Rev Toxicol 56(4):252-278; doi: 10.1080/10408444.2026.2661191. PMID: 42261678.

Buerger AN, Thompson CM, Heintz MM, Maberti S, Palermo CM, Haws LC. 2026. Application of quantitative and qualitative uncertainty assessment risk management decision-making: A case study with diisononyl phthalate. Food Chem Toxicol 214(Aug):116110; doi: 10.1016/j.fct.2026116110. PMID: 42035978.

Nguyen HVM, Hu F, Shakya E, Fender C, Lee K, Schindler J, Garcia-Jaramillo M, Ahsan N, et al. 2026. Mitochondrial-haplotype influences plasma metabolome, lipidome, and proteome in a sex specific manner in the genetically heterogenous OKC-HET^B/W rat. FASEB J 40(10):e71736; doi: 10.1096/fj.202502189RRR. PMID: 42171346.

Fender CL, Morshead M, Schindler J, Williamson M, Brown K, Cohen C, Feldman L, et al. 2026. Addressing community concerns about unregulated organic contaminants in surface water: Integrating suspect and non-targeted chemical analyses with Zebrafish toxicity testing and computational hazard comparisons. Environ Pollut 399(15 June):128103; doi: 10.1016/j.envpol.2026.128103. PMID: 41997357.

Bond G, Becker RA, Rish W, Ryman JP, Verwiel AH. 2026. Cumulative impact assessment within vulnerable communities: Challenges, opportunities and path forward. J Toxicol Regul Pol 2(1):1-19; doi: 10.69982/JTRP-25-0012.

Thompson CM, Heintz MM, Rogers SI, Vincent MJ, Haws LC. 2026. Integration of mechanistic and repeat dose toxicity data in the derivation of an oral reference dose for HFPO-DA. Toxicol Sci 209(5):kfag045; doi: 10.1093/toxsci/kfag045. PMID: 41968070.

Buerger AN, Heintz MM, Haws LC, Thompson CM. 2026. Mode-of-action and human relevance assessment for diisononyl phthalate-induced liver tumors in rodents. J Appl Toxicol; doi: 10.1002/jat.70223. Online ahead of print May 5th. PMID: 42086044. 

Pimenta K, Edwards J, Ray M, Naser AM, Price C, Idassi O, Strong K, Were W, et al. 2026. Contemporary global burden of sickle cell anaemia under-5 and under-20: A systematic review and meta-analysis. Br J Haematol 10.1111/bjh.70501. Online ahead of print May 3; doi: 10.1111/bjh.70501. PMID: 42070793.

Doepker C, Franzen A, Brorby G, Brown L, Choksi N, East A, Wikoff D. 2026. Smoke flavoring—A case study demonstrating the value of using benefit-risk analysis for foods (BRAFO) to provide transparency for risk management decisions. Regul Toxicol Pharmacol 167(May):106033; doi: 10.1016/j.yrtph.2026.106033. PMID: 41577161.

Lea IA, Buerger AN, Vincent MJ,…, Choksi NY, Schaefer H, Britt J, Fitch S, Haws L, Borghoff SJ. 2026. Evaluating the potential carcinogenic hazard of diisononyl phthalate in humans via systematic integration of human, animal cancer studies, and mechanistic data. Curr Res Toxicol 10(Apr 30):100295; doi: 10.1016/j.crtox.2026.100295.

Mahony C, Bartlett A, Fitzpatrick S, Galli C, Hunt P, Inselman A, Jimenez J,…, Rogers J, et al. 2026. A screening strategy for identifying the developmental and reproductive toxicity potential of botanicals. 64(1):639-557; doi: 10.1080/13880209.2026.2659421. PMID: 42048162.

Buerger AN, Vincent MJ, Fitch S, Rivera B, Engel N, Zhang J, Rushton EK, Borghoff SJ. 2026. A mechanistic evaluation of the metabolism disrupting potential of methyl tert-butyl ether. Curr Res Toxicol 10(Apr 20):100290; doi: 10.1016/j.crtox.2026.100290. PMID: 42057916.

Massarsky A, Evans VJB, Fung ES, Yang LGL, Rogers KL, Buerger AN, Maier A, Reichard JF. A framework for assessing the safety of degraded pharmaceuticals for long-duration space missions—Part II: Framework application in four case studies. Crit Rev Toxicol; doi: 10.1080/10408444.2026.2633422. Online ahead of print April 16. PMID: 41988975.