2025 (56 POSTS)
Patlewicz G , Judson, Paul Friedman K, Wetmore BA, DeVito MJ, Harrill JA, Carstens KE, Houck KA, et al. 2025. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs). J Toxicol Environ Health B online ahead of print July 6; doi: 10.1080/10937404.2025.2521615 . PMID: 40619890.
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Topics: NAMs , PFAS
Kenyon EM, DeVito MJ, Patlewicz G , Adams LD, Thomas RS, Ambroso JL, Yang X, Blake JC, et al. 2025. Subchronic toxicity of four per- and polyfluoroalkyl substances by oral exposure in Sprague Dawley rats. Toxics 13(7):524; doi: 10.3390/toxics13070524 . PMID: 40710969.
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Topics: PFAS
Leary A, Shah I, Patlewicz G . 2025. An exploration of the use of hybrid fingerprints in Generalized Read-Across and their impact on predictive performance for selected in vivo toxicity outcomes. Comput Toxicol 34(June):100349; doi: 10.1016/j.comtox.2025.100349 .
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Topics: NAMs , read-across
Hagan B, Shah I, Patlewicz G . 2025. Can graph similarity metrics be helpful for analogue identification as part of a read-across approach? Comput Toxicol 34(June):100353; doi: 10.1016/j.comtox.2025.100353 .
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Muller K, Unice K, Panko J , Wagner S. 2025. Tire emissions during the use phase of tires – Current and future trends. Environ Sci Adv 4(9):1344-1363; doi: 10.1039/d4va00407h .
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Topics: tire particles (TRWP)
Hughes MF, DeVito MJ, Patlewicz G , Thomas RS, Adams LD, Ambroso JL, Yang X, Upadhyay BG, et al. 2025. Immunotoxicity of four per- and polyfluoroalkyl substances following 28-day oral repeat dosing in rats assessed by the anti-sheep red blood IgM response. Toxics 13(6):490; doi: 10.3390/toxics13060490 . PMID: 40559963.
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Topics: PFAS
Brorby G, Franzen A, Thompson C, Wikoff D, Doepker C . 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490 . PMID: 40320068.
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Topics: food safety , Food science , genotoxicity , risk assessment , safety assessment
Hagan B, Groff L, Patlewicz G , Shah. 2025. Toward metabolic similarity in read-across: A case study using graph convolutional networks to predict genotoxicity outcomes. Chem Res Toxicol 38(6):1122-1133; doi: 10.1021/acs.chemrestox.5c00120 . PMID: 40432291.
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Topics: genotoxicity
Diemar MG, Giusti A, Michel-Caillet C, Leme DM, Wikoff D , Bloch D, Sass J, Beekmann K, et al. 2025. How to organize a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024. Arch Toxicol 99(7):3057-3063 ; doi : 10.1007/s00204-025-04064-6 . PMID: 40372420.
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Topics: chemical safety assessment , NAMs , risk assessment , safety assessment
Duong T, Haselkorn T, Miller B, Coats J, Jensen I , Ward E, Wood M, Graham RJ, Servais L. 2025. A real-world analysis of the impact of X-linked myotubular myopathy on caregivers in the United States. Orphanet J Rare Dis 20(1):224. doi: 10.1186/s13023-025-03583-w .
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Topics: Health Economics and Outcomes Research (HEOR)
Crincoli CM, van de Ligt JLG, Eapen AK. Pavel AT, Hanlon PR, Almond-Abbate K, Haugabrooks E,… Henderson RG . 2025. A tool to support food substance safety evaluations in the United States. Regul Toxicol Pharmacol 161(Sept):105838; doi: 10.1016/j.yrtph.2025.105838 . PMID: 40324559.
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Topics: food additives , food safety , Food science , risk assessment
Rogers JM, Heintz MM, Haws LC . 2025. Reproductive and developmental toxicity screen (OECD TG 421) and extended one generation reproductive toxicity study (OECD TG 443) of decahydronaphthalene in Sprague Dawley rats. Regul Toxicol Pharmacol 160(Aug):105829; doi: 10.1016/j.yrtph.2025.105829 . PMID: 40222475.
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Topics: Toxicology
Heintz MM , Buerger AN, Haws LC , Cullen JM, East AW, Thompson CM . 2025. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα , PPARγ , and cytotoxic agents in wild-type and Pparα -null mouse livers. Toxicol Sci 206(1):183-201; doi: 10.1093/toxsci/kfaf049 . PMID: 40216583.
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Topics: mode of action , transcriptomics
Lipke L, Price C . 2025. Rethinking systematic review assignment design in graduate health science education from librarians’ perspectives. Hypoth: Res J Health Info Prof 37(1); doi: 10.18060/28463 .
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Topics: Systematic Review
Nordyke RJ , Motyka J, Patterson JA. 2025. The association of 340B program drug margins with covered entity characteristics. Inquiry 62(Jan-Dec):469580251324051; doi: 10.1177/00469580251234051 . PMID: 4012322.
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Topics: Health Economics and Outcomes Research (HEOR)
Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC . 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152 . PMID: 39792025.
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Topics: PFAS , risk assessment , Systematic Review
Nguyen HVM, Cabello E, Dyer D, Fender C , Garcia-Jaramillo M, Hord NG, Austad S, Richardson A, Unnikrishnan A. 2025. Age, sex, and mitochrondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat. Aging 17(2):524-549; doi: 10.18632/aging.206211 . PMID: 40015964.
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Lea IA , Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221 . PMID: 40041033.
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Topics: phthalates
Kramer A , Vivanco S , Bare J , Panko J . 2025. Analysis of EPA air toxics monitoring data and tools for use in general population exposure assessments: Using acrylonitrile as a case study. J Air Waste Manag Assoc 75(3)181-197; doi: 10.1080/10962247.2024.2438793 . PMID: 39660961.
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