Publication Topic

Kramer M. AIHA exposure models toolbox. Virtual presentation, Occupational Hygiene Association of Ontario (OHAO) Fall Conference, Toronto, ON, Canada, October 2025.

Karamertzanis PG, Rasenberg M, Shah I, Patlewicz G. 2025. Modelling in vitro mutagenicity using multi-task deep learning and REACH data. Chem Res Toxicol 38(8):1382-1407; doi: 19.1021/acs.chemrestox.5c00152. PMID: 40680271.

Sweeney LM, Coyle JP, Covington TR, Sterner TR, Clewell RA. Rapid dosimetry in a tiered chemical screening process for military personnel-toxicokinetic considerations for a case study with in vitro neurotoxicity. Abstract 3495, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Cook B, Nelms M, Harris D, Bever RJ, Lynn SG, Williams D, Borghoff S, Edwards SW, Markey K. Identifying structural overlap between EDSP universe of chemicals and ToxCast/Tox21 using chemical clustering and uniform manifold approximation and projection. Abstract 4034, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Moyer H, Vergara L, Sakolish C, Stephan C, Barlow N, Roe H, Hewitt P, Villenave R, Rusyn I. Comparative analysis of drug permeability and toxicity in intestinal segment-specific membrane-based barrier model using Caco-2 and human jejunal and duodenal enteroid-derived cells. Abstract 3217, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.

Reynolds JI, Yelleti A, Johnson BP. Bridging data gaps in sonic hedgehog signaling: A novel microphysiological model approach. Abstract 3234, Society for Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Moyer HL, Vergara L, Stephan C, Sakolish C, Ford LC, Tsai HD, Lin HC, Chiu WA, et al. 2025. Comparative analysis of caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability. Toxicol Sci 204(2):181-197; doi: 10.1093/toxsci/kfaf011. PMID: 39886939.

Pennell ML, Wheeler MW, Auerbach SS. 2024. A hierarchical constrained density regression model for predicting cluster‐level dose‐response. Environmetrics 35(7):e2880; doi: 10.1002/env.2880.

Covington TR, Borghoff SJ, Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

Banerjee A, Kar S, Roy K, Patlewicz G, Charest N, Benfenati E, Cronin MTD. 2024. Molecular similarity in chemical informatics and predictive toxicity modeling: From quantitative read-across (q-RA) to quantitative read-across structure-activity relationship (q-RASAR) with the application of machine learning. Crit Rev Toxicol 54(9):659-684; doi: 10.1080/10408444.2024.2386260. PMID: 39225123.

Wilson KP, Valazza E, Price C. 2024. Video modeling to support social communication goals of autistic adults: A tutorial. Am J Speech Lang Pathol 33(5):2249–2265; doi: 10.1044/2024_AJSLP-23-00479.

Perry CS, Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698. PMID: 39251127.

Singh DK, Reynolds JI, Johnson BP. Low-cost laser welding for rapid prototyping of microfluidic, Lab-on-a-Chip, and microphysiological models. Mid-Michigan Symposium for Undergraduate Research Experiences, East Lansing, MI, 2024.

Moyer HL, Vergara L, Sakolish C, Lin HC, Hewitt P, Chiu WA, Stephan C, Rusyn I. Comparative analysis of caco-2 cells and human enteroids (jejeunal or duodenal) in gel- and membrane-based barrier models of intestinal permeability. Abstract 461, Microphysiological Systems (MPS) 3rd World Summit, Seattle, WA, June 2024.

Reynolds JI, Adams M, Johnson BP. Microplate micromachining for microphysiological model fabrication. Abstract 561, Microphysiological Systems (MPS) World Summit, Seattle, WA, 2024. https://proceedings.altex.org/data/2024_01/altex_MPS03.pdf

Groff L, Williams A, Shah I, Patlewicz G. 2024. MetSim: Integrated programmatic access and pathway management for xenobiotic metabolism simulators. Chem Res Toxicol 37(5):685-697; doi: 10.1021/acs.chemrestox.3c00398. PMID: 38598715.

Nelms MD, Antonijevic T, Ring C, Harris DL, Bever RJ, Lynn SG, … Borghoff S, et al. 2024. Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models. Front Toxicol 6(April 17):1346767; https://doi.org/10.3389/ftox.2024.1346767. PMID: 38694816.

Burnett J, Sychterz C, Zhu D, Shakeel F, Dingley K, Chen W, et al. Prospective application of physiologically based pharmacokinetic (PBPK) modeling to inform the design of a clinical drug-drug interaction (DDI) study: Case study of mezigdomide. Poster presented at American Society of Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting, Colorado Springs, CO, March 2024.

Edwards S, Antonijevic T, Nelms M, Ring C, Harris D,… Borghoff S, Markey K. Optimizing androgen receptor prioritization using high-throughput assay-based activity models. Abstract 4381, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Nelms M, Antonijevic T, Ring C, Harris D, Bever RJ,… Borghoff S, et al. Chemistry domain of applicability evaluation of estrogen receptor high-throughput assay-based activity models. Abstract 4380, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.