Publication Topic

Karamertzanis PG, Rasenberg M, Shah I, Patlewicz G. 2025. Modelling in vitro mutagenicity using multi-task deep learning and REACH data. Chem Res Toxicol 38(8):1382-1407; doi: 19.1021/acs.chemrestox.5c00152. PMID: 40680271.

Sweeney LM, Coyle JP, Covington TR, Sterner TR, Clewell RA. Rapid dosimetry in a tiered chemical screening process for military personnel-toxicokinetic considerations for a case study with in vitro neurotoxicity. Abstract 3495, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Moyer H, Vergara L, Sakolish C, Stephan C, Barlow N, Roe H, Hewitt P, Villenave R, Rusyn I. Comparative analysis of drug permeability and toxicity in intestinal segment-specific membrane-based barrier model using Caco-2 and human jejunal and duodenal enteroid-derived cells. Abstract 3217, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.

Reynolds JI, Yelleti A, Johnson BP. Bridging data gaps in sonic hedgehog signaling: A novel microphysiological model approach. Abstract 3234, Society for Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Moyer HL, Vergara L, Stephan C, Sakolish C, Ford LC, Tsai HD, Lin HC, Chiu WA, et al. 2025. Comparative analysis of caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability. Toxicol Sci 204(2):181-197; doi: 10.1093/toxsci/kfaf011. PMID: 39886939.

Pennell ML, Wheeler MW, Auerbach SS. 2024. A hierarchical constrained density regression model for predicting cluster‐level dose‐response. Environmetrics 35(7):e2880; doi: 10.1002/env.2880.

Covington TR, Borghoff SJ, Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

Banerjee A, Kar S, Roy K, Patlewicz G, Charest N, Benfenati E, Cronin MTD. 2024. Molecular similarity in chemical informatics and predictive toxicity modeling: From quantitative read-across (q-RA) to quantitative read-across structure-activity relationship (q-RASAR) with the application of machine learning. Crit Rev Toxicol 54(9):659-684; doi: 10.1080/10408444.2024.2386260. PMID: 39225123.

Wilson KP, Valazza E, Price C. 2024. Video modeling to support social communication goals of autistic adults: A tutorial. Am J Speech Lang Pathol 33(5):2249–2265; doi: 10.1044/2024_AJSLP-23-00479.

Perry CS, Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698. PMID: 39251127.

Singh DK, Reynolds JI, Johnson BP. Low-cost laser welding for rapid prototyping of microfluidic, Lab-on-a-Chip, and microphysiological models. Mid-Michigan Symposium for Undergraduate Research Experiences, East Lansing, MI, 2024.

Moyer HL, Vergara L, Sakolish C, Lin HC, Hewitt P, Chiu WA, Stephan C, Rusyn I. Comparative analysis of caco-2 cells and human enteroids (jejeunal or duodenal) in gel- and membrane-based barrier models of intestinal permeability. Abstract 461, Microphysiological Systems (MPS) 3rd World Summit, Seattle, WA, June 2024.

Reynolds JI, Adams M, Johnson BP. Microplate micromachining for microphysiological model fabrication. Abstract 561, Microphysiological Systems (MPS) World Summit, Seattle, WA, 2024. https://proceedings.altex.org/data/2024_01/altex_MPS03.pdf

Groff L, Williams A, Shah I, Patlewicz G. 2024. MetSim: Integrated programmatic access and pathway management for xenobiotic metabolism simulators. Chem Res Toxicol 37(5):685-697; doi: 10.1021/acs.chemrestox.3c00398. PMID: 38598715.

Burnett J, Sychterz C, Zhu D, Shakeel F, Dingley K, Chen W, et al. Prospective application of physiologically based pharmacokinetic (PBPK) modeling to inform the design of a clinical drug-drug interaction (DDI) study: Case study of mezigdomide. Poster presented at American Society of Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting, Colorado Springs, CO, March 2024.

Moyer H, Kim S, Lam BP, Richardson L, Menon R, Rusyn I, Han A. Fetal response to maternal exposures: Utility of a four-cell human organ-on-chip device to transport and effects of environmental chemicals. Abstract 4236, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. Winner, Reproductive and Developmental Toxicology Specialty Section Poster Award.

Russell AJ, Vincent M, Buerger AN, Dotson S, Lotter J, Maier A. 2024. Establishing short-term occupational exposure limits (STELs) for sensory irritants using predictive and in silico respiratory rate depression (RD50) models. Inhal Toxicol 36(1):13-25; doi: 10.1080/08958378.2023.2299867. PMID: 38252504.

Moyer H, Kim S, Lam BP, Valdiviezo A, Richardson L, Menon R, Rusyn I, Han A. Evaluating mechanistic underpinnings of environmental chemical effects on feto-maternal interface using a human organ-on-chip model. Lonestar Society of Toxicology Meeting, Houston, TX, December 2023.

Racz L, Mittal L, Perry CS, Blanchette A, Proctor D. Assessing sustainable applications of electric arc furnace steel slag as construction aggregate: Applications of probabilistic risk assessment and physiologically-based pharmacokinetic modeling. Poster presented at Society of Environmental Toxicology and Chemistry North America 44^th Annual Meeting, Louisville, KY, November 2023.

Kramer AJ. Introduction to inhalation exposure modeling. Technical presentation at AIHA Upper Midwest Local Section Professional Development Conference, Roseville, MN, November 2023.