2025 (2 POSTS)
Sweeney LM, Coyle JP, Covington TR , Sterner TR, Clewell RA. Rapid dosimetry in a tiered chemical screening process for military personnel-toxicokinetic considerations for a case study with in vitro neurotoxicity. Abstract 3495, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
Reynolds JI , Yelleti A, Johnson BP. Bridging data gaps in sonic hedgehog signaling: A novel microphysiological model approach. Abstract 3234, Society for Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
2024 (7 POSTS)
Covington TR , Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
Wilson KP, Valazza E, Price C. 2024. Video modeling to support social communication goals of autistic adults: A tutorial. Am J Speech Lang Pathol 33(5):2249–2265; doi: 10.1044/2024_AJSLP-23-00479 .
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Publication: Manuscripts
Perry CS , Verwiel AH , Covington TR , Proctor DM . 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698 . PMID: 39251127.
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Publication: Manuscripts
Singh DK, Reynolds JI , Johnson BP. Low-cost laser welding for rapid prototyping of microfluidic, Lab-on-a-Chip, and microphysiological models. Mid-Michigan Symposium for Undergraduate Research Experiences, East Lansing, MI, 2024.
Publication: Abstracts and Presentations
Reynolds JI , Adams M, Johnson BP. Microplate micromachining for microphysiological model fabrication. Abstract 561, Microphysiological Systems (MPS) World Summit, Seattle, WA, 2024. https://proceedings.altex.org/data/2024_01/altex_MPS03.pdf
Publication: Abstracts and Presentations
Burnett J, Sychterz C, Zhu D, Shakeel F, Dingley K , Chen W, et al. Prospective application of physiologically based pharmacokinetic (PBPK) modeling to inform the design of a clinical drug-drug interaction (DDI) study: Case study of mezigdomide. Poster presented at American Society of Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting, Colorado Springs, CO, March 2024.
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Publication: Abstracts and Presentations
Russell AJ, Vincent M , Buerger AN , Dotson S, Lotter J, Maier A. 2024. Establishing short-term occupational exposure limits (STELs) for sensory irritants using predictive and in silico respiratory rate depression (RD50) models. Inhal Toxicol 36(1):13-25; doi: 10.1080/08958378.2023.2299867 . PMID: 38252504.
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Publication: Manuscripts
2023 (8 POSTS)
Racz L , Mittal L , Perry CS , Blanchette A, Proctor D . Assessing sustainable applications of electric arc furnace steel slag as construction aggregate: Applications of probabilistic risk assessment and physiologically-based pharmacokinetic modeling. Poster presented at Society of Environmental Toxicology and Chemistry North America 44th Annual Meeting, Louisville, KY, November 2023.
Publication: Abstracts and Presentations
Perry CS , Blanchette AD, Vivanco SN , Verwiel AH , Proctor DM . 2023. Use of physiologically based pharmacokinetic modeling to support development of an acute (24-hour) health-based inhalation guideline for manganese. Regul Toxicol Pharmacol 145:105518; doi: 10.1016/j.yrtph.2023.105518 . PMID: 3786341.
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Publication: Manuscripts
Price S , Maddaloni M, Finley B , Thornton S, Unice K. 2023. Extending regulatory biokinetic lead models towards food safety: Evaluation of consumer baby food contribution to infant blood lead levels and variability. Foods 12(14):2732; doi: 103390/foods12142732 . PMID: 37509824.
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Publication: Manuscripts
Lawrenz M, Svensson M, Kato M, Dingley K , et al. 2023. A computational physics-based approach to predict unbound brain-to-plasma partition coefficient, Kp,uu. Chem Inf Model 63(12):3786–3798; doi: 10.121/acs.jcim.3c00150 . PMID: 37267072.
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Publication: Manuscripts
East A, Egeghy PP, Cohen Hubal EA, Slover R, Vallero DA. 2023. Computational estimates of daily aggregate exposure to PFOA/PFOS from 2011 to 2017 using a basic intake model. J Expos Sci Environ Epidemiol 33(1):56-68; doi: 10.1038/s41370-021-00374-w . PMID: 34373583.
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Publication: Manuscripts
Reynolds JI , Adams M, Johnson BP. Performance micromachining for creation of well plate based microphysiological models. Oral platform at Biomedical Engineering Society Annual Meeting, Seattle, WA, 2023.
Publication: Abstracts and Presentations
Wheeler MW . 2023. An investigation of non-informative priors for Bayesian dose-response modeling. Regul Toxicol Pharmacol 141(June):105389; doi: 10.1016/j.yrtph.2023.105389 . PMCID: PMC10436774.
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Publication: Manuscripts
East A , Dawson DE, Brady S, Vallero DA, Tornero-Velez R. 2023. A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models. Toxics 11(2):163; doi: 10.3390/toxics11020163 . PMID: 36851038.
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Publication: Manuscripts
2022 (5 POSTS)
Moran KR, Wheeler MW . 2022. Fast increased fidelity samplers for approximate Bayesian Gaussian process regression. J Roy Stat Soc B 84(4):1198-228; doi: 10.1111/rssb.12494 . PMCID: 36570797.
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Publication: Manuscripts
Wheeler MW , Cortiñas Abrahantes J, Aerts M, Gift JS, Allen Davis J. 2022. Continuous model averaging for benchmark dose analysis: Averaging over distributional forms. Environmetrics 33(5):e2728; doi: 10.1002/env.2728 . PMCID: PMC9799099.
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Publication: Manuscripts
Rivera BN , Wilson LB, Kim DM, Pande P, Anderson KA, Tilton SC, Tanguay RL. 2022. A comparative multi-system approach to characterizing bioactivity of commonly occurring chemicals. Int J Environ Res Public Health 19(7):3829; doi: 10.3390/ijerph19073829 . PMID: 35409514.
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