2025 (1 POST)
Sweeney LM, Coyle JP, Covington TR , Sterner TR, Clewell RA. Rapid dosimetry in a tiered chemical screening process for military personnel-toxicokinetic considerations for a case study with in vitro neurotoxicity. Abstract 3495, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Publication: Abstracts and Presentations
2024 (5 POSTS)
Covington TR , Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Publication: Abstracts and Presentations
Wilson KP, Valazza E, Price C. 2024. Video modeling to support social communication goals of autistic adults: A tutorial. Am J Speech Lang Pathol 33(5):2249–2265; doi: 10.1044/2024_AJSLP-23-00479 .
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Publication: Manuscripts
Perry CS , Verwiel AH , Covington TR , Proctor DM . 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698 . PMID: 39251127.
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Publication: Manuscripts
Burnett J, Sychterz C, Zhu D, Shakeel F, Dingley K , Chen W, et al. Prospective application of physiologically based pharmacokinetic (PBPK) modeling to inform the design of a clinical drug-drug interaction (DDI) study: Case study of mezigdomide. Poster presented at American Society of Clinical Pharmacology and Therapeutics (ASCPT) Annual Meeting, Colorado Springs, CO, March 2024.
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Publication: Abstracts and Presentations
Russell AJ, Vincent M , Buerger AN , Dotson S, Lotter J, Maier A. 2024. Establishing short-term occupational exposure limits (STELs) for sensory irritants using predictive and in silico respiratory rate depression (RD50) models. Inhal Toxicol 36(1):13-25; doi: 10.1080/08958378.2023.2299867 . PMID: 38252504.
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Publication: Manuscripts
2023 (7 POSTS)
Racz L , Mittal L , Perry CS , Blanchette A, Proctor D . Assessing sustainable applications of electric arc furnace steel slag as construction aggregate: Applications of probabilistic risk assessment and physiologically-based pharmacokinetic modeling. Poster presented at Society of Environmental Toxicology and Chemistry North America 44th Annual Meeting, Louisville, KY, November 2023.
Publication: Abstracts and Presentations
Perry CS , Blanchette AD, Vivanco SN , Verwiel AH , Proctor DM . 2023. Use of physiologically based pharmacokinetic modeling to support development of an acute (24-hour) health-based inhalation guideline for manganese. Regul Toxicol Pharmacol 145:105518; doi: 10.1016/j.yrtph.2023.105518 . PMID: 3786341.
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Publication: Manuscripts
Price S , Maddaloni M, Finley B , Thornton S, Unice K. 2023. Extending regulatory biokinetic lead models towards food safety: Evaluation of consumer baby food contribution to infant blood lead levels and variability. Foods 12(14):2732; doi: 103390/foods12142732 . PMID: 37509824.
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Publication: Manuscripts
Lawrenz M, Svensson M, Kato M, Dingley K , et al. 2023. A computational physics-based approach to predict unbound brain-to-plasma partition coefficient, Kp,uu. Chem Inf Model 63(12):3786–3798; doi: 10.121/acs.jcim.3c00150 . PMID: 37267072.
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Publication: Manuscripts
East A, Egeghy PP, Cohen Hubal EA, Slover R, Vallero DA. 2023. Computational estimates of daily aggregate exposure to PFOA/PFOS from 2011 to 2017 using a basic intake model. J Expos Sci Environ Epidemiol 33(1):56-68; doi: 10.1038/s41370-021-00374-w . PMID: 34373583.
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Publication: Manuscripts
Wheeler MW . 2023. An investigation of non-informative priors for Bayesian dose-response modeling. Regul Toxicol Pharmacol 141(June):105389; doi: 10.1016/j.yrtph.2023.105389 . PMCID: PMC10436774.
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Publication: Manuscripts
East A , Dawson DE, Brady S, Vallero DA, Tornero-Velez R. 2023. A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models. Toxics 11(2):163; doi: 10.3390/toxics11020163 . PMID: 36851038.
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Publication: Manuscripts
2022 (5 POSTS)
Moran KR, Wheeler MW . 2022. Fast increased fidelity samplers for approximate Bayesian Gaussian process regression. J Roy Stat Soc B 84(4):1198-228; doi: 10.1111/rssb.12494 . PMCID: 36570797.
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Publication: Manuscripts
Wheeler MW , Cortiñas Abrahantes J, Aerts M, Gift JS, Allen Davis J. 2022. Continuous model averaging for benchmark dose analysis: Averaging over distributional forms. Environmetrics 33(5):e2728; doi: 10.1002/env.2728 . PMCID: PMC9799099.
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Publication: Manuscripts
Rivera BN , Wilson LB, Kim DM, Pande P, Anderson KA, Tilton SC, Tanguay RL. 2022. A comparative multi-system approach to characterizing bioactivity of commonly occurring chemicals. Int J Environ Res Public Health 19(7):3829; doi: 10.3390/ijerph19073829 . PMID: 35409514.
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Publication: Manuscripts
Racz L , Rish W . 2022. Exposure monitoring toward environmental justice. Integ Environ Assess Manag 18(4):858-862; doi: 10.1002/ieam.4534 . PMID: 34633140.
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Publication: Manuscripts
Tornero-Velez R, Dawson D, East A , Breen M, Brady S, Vallero D, Hubal EC, Wambaugh, J. Using systematic evidence mapping to track the development of toxicokinetic models of PFAS from 2000–2021. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022; doi: 10.23645/epacomptox.19333283 .
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Publication: Abstracts and Presentations
2021 (6 POSTS)
Moran KR, Dunson D, Wheeler MW , Herring AH. 2021. Bayesian joint modeling of chemical structure and dose response curves. Ann Appl Stat 15(3):1405; doi: 10.214/21-aoas1461. PMCID: PMC9236276.
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Publication: Manuscripts
East A , Dawson D, Glen G, Isaacs K, Dionisio K, Price PS, et al. 2021. The Residential Population Generator (RPGen): Parameterization of residential, demographic, and physiological data to model intraindividual exposure, dose, and risk. Toxics 9(11):303; doi: 10.3390/toxics9110303 .
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