Publication Topic

Wikoff D. An introduction to evidence integration. Workshop Session, Abstract 1333, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Wikoff D, Fitch S, Vincent M, Southall MD, Atillasoy E, Weinstein RD, Ejaz SD, Rhoden JD, Choksi N. Biological plausibility assessment of acetaminophen and occurrence of developmental neurological outcomes in humans. Abstract 4768, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Vincent M. The critical role of biological plausibility in evidence integration. Abstract 1336, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Thompson CM, Heintz MM, Cullen JM, Haws LC. Evaluation of the chronic toxicity and carcinogenicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate (HFPO-DA) in mice. Abstract 4700, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Sweeney LM, Coyle JP, Covington TR, Sterner TR, Clewell RA. Rapid dosimetry in a tiered chemical screening process for military personnel-toxicokinetic considerations for a case study with in vitro neurotoxicity. Abstract 3495, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Stemer TR, Covington TR, Cowan DW, Coyle JP, Gearhart JM, LaLonde TJ, Ring CL, Sweeney LM, Wambaugh JF, Wooten AT, Bang AG, Clewell RA. Rapid risk assessment of potential neurotoxicants using non-animal test methods. Abstract 4842, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Rogers JM, Heintz MM, Haws LC. Reproduction/developmental toxicity screen and extended one generation reproductive toxicity study of decahydronaphthalene in Sprague Dawley rats. Abstract 3864, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Mihalchik A. Strategies to evaluate over-the-counter drug degradants. Abstract 1252, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Lea IA, Holt J, Bunnage E, Long M, Chew R, Bell S, Edwards S, Sayre R, Vliet SM, Lynn SG, Kristan MJ. Integrated computational approaches in systematic evidence mapping: Bridging human expertise and machine learning for advanced toxicological assessments. Abstract 3409, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Klaren W. Targeted state of the science scoping review for incorporating stress within experimental models of chemical toxicity. Abstract 1260, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Klaren W. Incorporating stress as a variable into toxicological testing: Advancing our understanding of cumulative impacts. Abstract 1259, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Heintz MM, Buerger AN, Haws LC, East AW, Cullen JM, Thompson CM. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mice. Abstract 3972, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025

Fitch S, Wikoff D, Foreman J, Buerger A, Haws L, Palmero C. Assessment of relative potency factors for six phthalates. Abstract 4235, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Cook B, Nelms M, Harris D, Bever RJ, Lynn SG, Williams D, Borghoff S, Edwards SW, Markey K. Identifying structural overlap between EDSP universe of chemicals and ToxCast/Tox21 using chemical clustering and uniform manifold approximation and projection. Abstract 4034, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC. 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152. PMID: 39792025.

Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE. 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030.  PMID: 39873747.

Bates CA, Vincent MJ, Buerger AN, Santamaria AB, Maier A, Jack M. 2024. Investigating the relationship between β-carotene intake from diet and supplements, smoking, and lung cancer risk. Food Chem Toxicol 194:115104; doi: 10.1016/j.fct.2024.115104. PMID: 39522798.

Haber LT, Bradley MA, Buerger AN, Behrsing H, Burla S, Clapp PW, et al. 2024. New approach methodologies (NAMs) for the in vitro assessment of cleaning products for respiratory irritation: Workshop report. Front Toxicol 6:1431790; doi: 10.3389/ftox.2024.1431790. eCollection 2024. PMID: 39439531.

Mattes RD, Rivera BN, Rutigliani GR, Rogers S, Mendoza ID, Wang L, Beckemeier K, Wikoff D. 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723.

Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S, et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.