Publication Topic

Nelms MD, Antonijevic T, Ring C, Harris DL, Bever RJ, Lynn SG, … Borghoff S, et al. 2024. Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models. Front Toxicol 6:https://doi.org/10.3389/ftox.2024.1346767.

Mittal L, Perry C, Blanchette AD, Proctor DM. 2024. Probabilistic risk assessment of residential exposure to electric arc furnace steel slag using Bayesian model of relative bioavailability and PBPK modeling of manganese. Risk Analysis, open access.

Heintz MM, Klaren WD, East AW, Haws LC, McGreal SR, Campbell RR, Thompson CM. 2024. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in mouse, rat, and pooled human hepatocytes. Toxicol Sci kfae044. doi: 10.1093/toxsci/kfae044. Online ahead of print. PMID: 38574381

Heintz MM, Klaren WD, East AW, Haws LC, McGreal SR, Campbell RR, Thompson CM. 2024. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mouse hepatocytes. Toxicol Sci kfae045. doi: 10.1093/toxsci/kfae045. Online ahead of print. PMID: 38574385.

Fitch S, Ellis-Hutchings R, Rogers J, Marty S, Rushton E,… Wikoff D. Study quality evaluation of literature reporting plastic microparticle exposure against reproductive and developmental toxicity endpoints. Abstract 5159, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Vincent M, Fitch S, Bylsma L, Thompson C, Rogers S, Britt J, Wikoff D. Integration of toxicological and epidemiological information to evaluate biological plausibility and causality of associations between inhaled formaldehyde (FA) and lymphohematopoietic (LHP) cancers. Abstract 5157, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024. 

Urban JD, Covington TR, Fitch SE, Wikoff DS. Dioxin-like compounds in soils: A pilot survey updating background soil TEQ. Abstract 5147, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024. 

Perry CS, Vivanco SN, Verwiel AH, Proctor DM. Derivation of manganese 24-hour acute inhalation guideline protective of respiratory and neurological effects. Abstract 4751, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Edwards S, Antonijevic T, Nelms M, Ring C, Harris D,… Borghoff S, Markey K. Optimizing androgen receptor prioritization using high-throughput assay-based activity models. Abstract 4381, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Nelms M, Antonijevic T, Ring C, Harris D, Bever RJ,… Borghoff S, et al. Chemistry domain of applicability evaluation of estrogen receptor high-throughput assay-based activity models. Abstract 4380, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024. 

Lynn SG, Lea IA, Urban J, Borghoff SJ, Wikoff D, Fitch S, Perry C, Choksi N, Britt J, Heintz M, Klaren W, et al. Development and application of systematic approach to inventory and interrogate thyroid hormone network information. Abstract 4357, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024. 

Borghoff SJ, Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Lea IA. Evaluation of the endocrine disrupting potential of di-isodecyl phthalate. Abstract 3931, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024. 

Lea IA, Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Borghoff SJ. Evaluation of the endocrine disrupting potential of di-isodecyl phthalate. Abstract 3930, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Allen B, Vincent M, Lipword L, Panko J, Suh M, Jiang X, Mumma, Proctor D. Lung cancer risk and exposure to hexavalent chromium: Results of extended mortality study of workers with low level exposures and quantitative risk assessment using pooled analysis of three cohorts. Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Thompson CM, Heintz MM, Rogers SI, Fitch SE, Rivera BN, Klaren WD, Vincent MJ, Wikoff DS, Haws LC. Evidence identification and appraisal supporting development of an updated toxicity value for HFPO-DA. Abstract 3654, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Heintz M, Klaren W, East A, Haws L, Thompson C. Delayed transcriptomic responses in PPARa knockout mouse hepatocytes compared to wild-type hepatocytes exposed to HFPO-DA or PPARa agonist GW7647: Support for a PPARa-dependent mode of action for HFPO-DA in mouse hepatocytes. Abstract 4100, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

DeVito, Bokkers B, van Duursen M, van Ede K, Feeley M,… Haws L,… Wikoff D, et al. The 2022 WHO reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls. Abstract 3626, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Petrick J, Mihalchik A, Tiwary A, Kreidl L, Swartz C, Bhattarai N. Nonclinical safety evaluation of 1-monoacetin and 2-monoacetin as potential impurities in pharmaceutical excipients. Abstract 3107, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Franke K, Vincent M, Rogers S, Rivera B, Wikoff D. Assessment of non-occupational exposures to cleaning products and the incidence of asthma and respiratory disease. Abstract 3393, Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2024.

Bever RJ, Edwards SW, Antonijevic T, Nelms MD, Ring C, Harris D, Lynn SG, Williams D, Chappell G, Boyles R, Borghoff S, Markey KJ. 2024. Optimizing androgen receptor prioritization using high-throughput assay-based activity models. Front Toxicol 6:1347364; doi: 10.3389/ftox.2024.1347364.