Publication Topic

Kenyon MO, Martin M, Martin EA, Brandstetter S, Wegesser T, Greene N, Harvey J. 2024. Deriving acceptable limits for non-mutagenic impurities in medicinal products–Durational adjustments. Regul Toxicol Pharmacol 150(June):105644; doi: 10.1016/j.yrtph.2024.105644. PMID: 38761968.

Madl AK, Donnell MT, Covell L. Synthetic vitreous fibers (SVFs): Adverse outcome pathways (AOPs) and considerations for new generation new approach methods (NAMs). Poster presentation P863/Abstract 4288, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Patlewicz G, Shah I. 2023. Towards systematic read-across using Generalized Read-Across (GenRA). Comput Toxicol 25(Feb):100258; doi: 10.1016/j.comtox.2022.100258. PMID: 37693774.

Adams M, Hilde H, Chang D, Richard A, Williams AJ, Shah I, Patlewicz G. 2023. Development of a CSRML version of the Analog Identification Methodology (AIM) fragments and their evaluation within the Generalized Read-Across (GenRA) approach. Comput Toxicol 25(Feb):100256; doi: 10.1016/j.comtox.2022.100256. PMID: 36733411.

Lizarraga L, Suter GW, Lambert JC, Patlewicz G, Zhao JQ, Dean JL, Kaiser P. 2023. Advancing the science of a read-across framework for evaluation of data poor chemicals incorporating systematic and new approach methods. Regul Toxicol Pharm 137(Jan):105293; doi: 10.1016/j.yrtph.2022.105293. PMID: 36414101.

Cronin MTD, Bauer FJ, Bonnell M, Campos B, Ebbrell DJ, Firman JW, Gutsell S, Hodges G, Patlewicz G, et al. 2022. A scheme to evaluate structural alerts to predict toxicity–Assessing confidence by characterizing uncertainties. Regul Toxicol Pharmacol 135(Nov):105249; doi: 10.1016/j.yrtph.2022.105249. PMID: 36041585.

Patlewicz G, Richard AM, Williams AJ, Judson RS, Thomas RS. 2022. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. Comput Toxicol 24(Nov):100250; doi: 10.1016/j.comtox.2022.100250. PMID: 36969381.

Foster MJ, Patlewicz G, Shah I, Haggard DE, Judson RS, Paul Friedman K. 2022. Evaluating structure-based activity in a high throughput assay for steroid biosynthesis. Comput Toxicol 24(Nov):100245; doi: 10.1016/j.comtox.2022.100245. PMID: 37841081.

Ponder J, Rajagopal R, Singal M, Baker N, Patlewicz G, Roggen E, Cochrane S, Sullivan K. 2022. “In Litero” screening. Retrospective evaluation of clinical evidence to establish a reference list of human chemical respiratory sensitizers. Front Toxicol 4(Jul 15):916370; doi: 10.3389/ftox.2022.916370. PMID: 35910543.

Karmaus A, Mansouri K, To K, Blake B, Fitzpatrick J, Strickland J, Patlewicz G, Allen D, et al. 2022. Evaluation of variability across rat acute oral systemic toxicity studies. Toxicol Sci 188(1):34-47; doi: 10.1093/toxsci/kfac042. PMID: 35426934.

Patlewicz G. 2022. Editorial: Reflections of the QSAR2021 meeting. Comput Toxicol 22(May):100221; doi: 10.1016/j.comtox.2022.100221. PMID: 35252631.

Rooney J, Abedini J, Bell S, Chang X, Cook B, Ceger P, Choksi N, et al. Building confidence in alternative methods through ICE. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Allen DG, Rooney J, To K, Choksi N, Ceger P, Daniel A, et al. Variability in reference test method data and the impact on NAM evaluations. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Boyce M, Meyer B, Grulke C, Lizarraga L, Patlewicz G. 2022. Comparing the performance and coverage of selected in silico (liver) metabolism tools related to reported studies in the literature to inform analogue selection in read-across: A case study. Comput Toxicol 21(Feb):100208; doi: 10.1016/j.comtox.2021.100208. PMID: 35386221.

Beal MA, Gagne M, Kulkarni SA, Patlewicz G, Thomas RS, Barton-Maclaren TS. 2022. Implementing in vitro bioactivity to modernize priority setting of chemical inventories. ALTEX 39(1):123-139; doi: 10.14573/altex.2106171. PMID: 34818430.

Shah I, Tate T, Patlewicz G. 2021. Generalized Read-Across prediction using genra-py. Bioinformatics 37(19):3380-3381; doi: 10.1093/bioinformatics/btab210. PMID: 33772575.

Rooney JP, Choksi NY, Ceger P, Daniel AB, Truax J, Allen D, Kleinstreuer N 2021. Analysis of variability in in vivo rabbit skin irritation assay results. Regul Toxicol Pharmacol 122(June):104920; doi: 10.1016/j.yrtph.2021.104920. PMID: 33757807.

Pangburn HA, Linakis MW, Chushak YG, Covington TR, McCarthy MJ, Gearhart JM. New approach methodologies informing operational Air Force mission. Presentation, Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Rovida C, Escher SE, Herzler M, Bennekou SH, Kamp H, Kroese DE, Maslankiewicz L, Moné MJ, Patlewicz G, et al. 2021. NAM-supported read-across: From case studies to regulatory guidance in safety assessment. ALTEX 38(1):140-150; doi: 10.14573/altex.2010062. PMID: 33452529.

Gao R, Guan N, Huang M, Foreman J, Kung M, Rong Z, Su Y, Sweet L, et al. 2020. Read-across: Principle, case study and its potential regulatory application in China. Regul Toxicol Pharmacol 116(Oct):104728; doi: 10.1016/j.yrtph.2020.104728. PMID: 32649957.