This will be the seventh webinar in the Risk Assessment Syllabus series, which began in 2021. This webinar will bring together many of the concepts covered in prior topics to show how new approach methodologies (NAMs) can transform the human health risk assessment to advance more predictive, efficient, and human-relevant risk evaluations. The webinar will examine the next-generation risk assessment framework, its emergence as an industry best practice, and its potential applications in regulatory settings.