Publication Topic

Wambaugh JF, Sipes NS, Padilla Mercado G, Arnot JA, Bertato L, Brown TN, Chirico N,…, Patlewicz G, et al. 2026. Collaborative evaluation of in silico predictions for high throughput toxicokinetics. Toxicol In Vitro 110(Jan):106150; doi: 10.1016/j.tiv.2025.106150. ePub September 20, 2025. PMID: 40983213.

East A, Dawson DE, Brady S, Vallero DA, Tornero-Velez R. 2023. A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models. Toxics 11(2):163; doi: 10.3390/toxics11020163. PMID: 36851038.

Beal MA, Gagne M, Kulkarni SA, Patlewicz G, Thomas RS, Barton-Maclaren TS. 2022. Implementing in vitro bioactivity to modernize priority setting of chemical inventories. ALTEX 39(1):123-139; doi: 10.14573/altex.2106171. PMID: 34818430.

Belair DG, Sudak K, Connelly K, Collins ND, Kopytek SJ, Kolaja KL. 2021. Investigation into the role of ERK in tyrosine kinase inhibitor-induced neuropathy. Toxicol Sci 181(2):160–174; doi: 10.1093/toxsci/kfab033. PMID: 33749749.

Ring C, Sipes NS, Hsieh JH, Carberry C, Koval LE, Klaren WD, Harris MA, Auerbach SS, Rager JE. 2021. Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high throughput toxicokinetics. Comput Toxicol 18(May):100166; doi: 10.1016/j.comtox.2021.100166. PMID: 34013136.

Pradeep P, Patlewicz G, Pearce R, Wambaugh J, Wetmore B, Judson R. 2020. Using chemical structure information to develop predictive models for in vitro toxicokinetic parameters to inform high-throughput risk-assessment. Comput Toxicol 16(Nov):100136; doi: 10.1016/j.comtox.2020.100136. PMID: 34124416.

Nelms MD, Lougee R, Roberts DW, Richard A, Patlewicz G. 2019. Comparing and contrasting the coverage of publicly available structural alerts for protein binding. Comput Toxicol 12(Nov):100100; doi: 10.1016/j.comtox.2019.100100. PMID: 37701288.

Thomas RS, Bahadori T, Buckley T, Cowden J, Deisenroth C, Dionisio K, Frithsen J,…, Patlewicz G, et al. 2019. The next generation of computational toxicology at the US Environmental Protection Agency. Toxicol Sci 169(2):317-332; doi: 10.1093/toxsci/kfz058. PMID: 30835285.

Patlewicz G, Richard AM, Williams AJ, Grulke CM, Sams R, Lambert J, Noyes P, DeVito MJ, et al. 2019. A chemical category-based prioritization approach for selecting 75 per- and polyfluoroalkyl substances (PFAS) for tiered toxicity and toxicokinetic testing. Environ Health Perspect 127(1):14501; doi: 10.1289/EHP4555. PMID: 30632786.

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells. Annual Biomedical Research Conference for Minority Students (ABRCMS), Indianapolis, IN, November 2018.

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells. Research Experiences for Undergraduates (REUs), Alexandria, VA, October 2018.

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells. Clemson Summer Research Symposium, July 2018.

Mihalchik AL, Rogers EN. 2018. Classes of compounds with GI tract toxicity. Chapter 13 in: Gad SC (ed), Toxicology of the Gastrointestinal Tract. CRC Press.

Rasmussen CE, Nowak J, Larsen JM, Bottomley A, Rowles A, Offenberg H. 2016. Evaluation of nonacog beta pegol long-term safety in the immune-deficient Rowett nude rat (Cro:NIH-Foxn1rnu). Toxicol Pathol 44(5):726–737; doi: 10.1177/0192623316633311. PMID: 26940713.

Bottomley AL, Rowles A, Mitchell DJ, Rasmussen AD. 2015. Detection of mild and reversible neurohistopathological changes in the brain of juvenile (preweaned) beagle dogs treated with vigabatrin for up to 91 days. Toxicol Pathol 43(7):1015-24; doi: 10.1177/0192623315591838. PMID: 26157036.

Tvermoes BE, Paustenbach DJ, Kerger BD, Finley BL, Unice KM. 2015. Review of cobalt toxicokinetics following oral dosing: Implications for health risk assessments and metal-on-metal hip implant patients. Crit Rev Toxicol 45(5):367–387.

Kirman CR, Proctor DM, Suh M, Hays S. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Kirman CR, Thompson CM, Proctor DM, Suh M, Haws LC, Harris MA, Hays SM. Using PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.

Staskal-Wikoff D, Budinsky R, Rowlands JC. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

Britt JK, James RC. 2007. Toxicology. In: Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc., Hoboken, NJ. pp. 201-252.