Publication Topic

DeVito M, Bokkers B, van Duursen MBM, van Ede K, Feeley M, Antunes Fernandes Gaspar E, Haws L,… Wikoff DD, et al. 2024. The 2022 World Health Organization reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls. Regul Toxicol Pharmacol 146(Jan):105525; doi: 10.1016/j.yrtph.2023.105525.

Ring C, Blanchette A, Klaren WD, Fitch S, Haws L, Wheeler MW, DeVito MJ, Walker N, Wikoff D. 2023. A multi-tiered hierarchical Bayesian approach to derive toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 143(11):105464; doi: 10.1016/j.yrtph.2023.105464.

Wikoff D, Ring C, DeVito M, Walker N, Birnbaum L, Haws L. 2023. Development and application of a systematic and quantitative weighting framework to evaluate the quality and relevance of relative potency estimates for dioxin-like compounds (DLCs) for human health risk assessment. Regul Toxicol Pharmacol 145:105500; doi: 10.1016/j.yrtph.2023.105500.

Ring C, Fitch S, Haws L, Harris M, Wikoff D. Quantitative integration of dose-response data for relative potency estimates of dioxin-like chemicals. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

Wikoff D, Haws L, Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol 39(9):1293-1310; doi: 10.1002/jat.3814.

Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Wikoff D, Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Bichteler A, Wikoff DS, Loko F, Harris MA. 2017. Estimating serum concentrations of dioxin-like compounds in the U.S. population effective 2005-2006 and 2007-2008: A multiple imputation and trending approach incorporating NHANES pooled sample data. Environ Int 105(Aug):112-125; doi: 10.1016/j.envint.2017.05.003.

Thompson CM, Suh M, Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Urban JD, Wikoff DS, Bunch ATG, Harris MA, Haws LC. 2014. A review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels. Sci Tot Environ 466-467:(Jan 1)586-597; doi: 10.1016/j.scitotenv.2013.07.065.

Dourson ML, Gadagbui B, Griffin S, Garabrant DH, Haws LC, Kirman C, Tohyama C. 2013. The importance of problem formulations in risk assessment: A case study involving dioxin-contaminated soil. Regul Toxicol Pharmacol 66(2):208-216; doi: 10.1016/j.yrtph.2013.03.010.

Rowlands JC, Budinsky R, Gollapudi B, Black MB, Wolfinger RD, Cukovic D, Bombkowski A, Thompson CM, Urban JD, Thomas RS. 2013. A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes. Toxicol Sci 136(2):595-604; doi: 10.1093/toxsci/kft203.

Haws L, Hixon G, DeVito M, Walker N, Kuriakose L, Harris M, Birnbaum L, Wikoff D. Development of weighted distributions of relative potency estimates for dioxin-like compounds. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.

Haws L, Fitzgerald L, Burkhalter K, Wikoff D. US EPA’s proposed toxicity values for TCDD: Implications for decision-making regarding the safety of foods in the United States. Presented at the Society of Toxicology’s 51st Annual Meeting, San Francisco, CA, March 2012.

Urban J, Rowlands JC, Budinsky R, Dombkowski A, Thompson CM, Thomas RS. A genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Wikoff D, DeVito M, Walker N, Hixon G, Harris M, Tachovsky A, Birnbaum L, Haws L. Application of machine learning in the development of a weighting framework for evaluating estimates of relative potency for dioxin-like compounds. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Diliberto JJ, Sirinek L, Burkhalter B, Wikoff DS, Hixon G, Becker J, Patterson DG, Turner W, Tachovsky JA, Birnbaum LS, Haws LC. Endometriosis in a cohort of women living in the Kanawha River Valley in West Virginia: Blood levels of non-dioxin-like PCBs and relationship with BMI and age. Presented at Dioxin 2011, Brussels, Belgium, August 2011.

Haws LC, DeVito MJ, Walker NJ,Harris MA, Tachovsky JA, Birnbaum LS, Farland WH, Wikoff DS. Development of a consensus-based weighting framework for evaluating estimates of relative potency for dioxin-like compounds that includes consideration of data from human cells. Presented at Dioxin 2011, Brussels, Belgium, August 2011.

Haws LC, Fitzgerald L, Burkhalter B, Harris M, Wikoff DS. Assessment of the US EPA’s proposed toxicological values for TCDD for regulation of dioxin-like compounds in foods: Bridging the science divide in a global market. Presented at Dioxin 2011, Brussels, Belgium, August 2011.

Rowlands JC, Urban J, Wikoff DS, Budinsky R. The presence and estimated functional effect of single nucleotide polymorphisms at the AIP, ARNT, HSP90AA1, AND HSP90AB1 loci in the human population. Presented at Dioxin 2011, Brussels, Belgium, August 2011.