Publication Topic

Urban JD, Covington TR, Fitch SE, Wikoff DS. Dioxin-like compounds in soils: A pilot survey updating background soil TEQ. Abstract 5147, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. 

DeVito, Bokkers B, van Duursen M, van Ede K, Feeley M,… Haws L,… Wikoff D, et al. The 2022 WHO reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls. Abstract 3626, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Fitch S, Blanchette A, Haws LC, Franke K, Ring C, DeVito M, Wheeler M,… Wikoff DS. 2024. Systematic update to the mammalian relative potency estimate database and development of best estimate toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 147(Feb):105571; doi: 10.1016/j.yrtph.2024.105571. PMID: 38244664.

DeVito M, Bokkers B, van Duursen MBM, van Ede K, Feeley M, Antunes Fernandes Gaspar E, Haws L,… Wheeler M,… Wikoff D, et al. 2024. The 2022 World Health Organization reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls. Regul Toxicol Pharmacol 146(Jan):105525; doi: 10.1016/j.yrtph.2023.105525. PMID: 37972849.

Ring C, Blanchette A, Klaren WD, Fitch S, Haws L, Wheeler MW, DeVito MJ, Walker N, Wikoff D. 2023. A multi-tiered hierarchical Bayesian approach to derive toxic equivalency factors for dioxin-like compounds. Regul Toxicol Pharmacol 143(11):105464; doi: 10.1016/j.yrtph.2023.105464. PMID: 37516304.

Wikoff D, Ring C, DeVito M, Walker N, Birnbaum L, Haws L. 2023. Development and application of a systematic and quantitative weighting framework to evaluate the quality and relevance of relative potency estimates for dioxin-like compounds (DLCs) for human health risk assessment. Regul Toxicol Pharmacol 145:105500; doi: 10.1016/j.yrtph.2023.105500. PMID: 37866700.

Wikoff DS, Urban JD, Ring C, Britt J, Fitch S, Haws LC. 2021. Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression. Toxicol Sci 179(2):162-182; doi: 10.1093/toxsci/kfaa171.

Ring C, Fitch S, Haws L, Harris M, Wikoff D. Quantitative integration of dose-response data for relative potency estimates of dioxin-like chemicals. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

Killius A, Finley BL. Analyzing the effect of pooled samples on interpreting the NHANES dioxin serum data. Virtual poster presentation at Society of Toxicology 59th Annual Meeting, Virtual, 2020.

Killius A, Finley BL. Dioxin and furan congener contributions to blood TEQ in the current NHANES database. Society of Toxicology 59th Annual Meeting, Virtual, 2020.

Perry C, Rish W, Ring C, Mittal L, Harris M. Use of probabilistic risk assessment and physiologically based pharmacokinetic modeling in supporting soil remedial objectives for dioxins and furans at a Canadian site. Poster for Society for Risk Analysis, Virtual Annual Meeting, 2020.

Wikoff D, Haws L, Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol 39(9):1293-1310; doi: 10.1002/jat.3814.

Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Urban J, Wikoff D, Haws L, Fitch S, Ring C, Thompson C, Suh M. 2018. Systematic review protocol: Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count. Zenodo. http://doi.org/10.5281/zenodo.1636357.

Wikoff D, Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Bichteler A, Wikoff DS, Loko F, Harris MA. 2017. Estimating serum concentrations of dioxin-like compounds in the U.S. population effective 2005-2006 and 2007-2008: A multiple imputation and trending approach incorporating NHANES pooled sample data. Environ Int 105(Aug):112-125; doi: 10.1016/j.envint.2017.05.003.

Thompson CM, Suh M, Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Urban JD, Wikoff DS, Bunch ATG, Harris MA, Haws LC. 2014. A review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels. Sci Tot Environ 466-467:(Jan 1)586-597; doi: 10.1016/j.scitotenv.2013.07.065.

Dourson ML, Gadagbui B, Griffin S, Garabrant DH, Haws LC, Kirman C, Tohyama C. 2013. The importance of problem formulations in risk assessment: A case study involving dioxin-contaminated soil. Regul Toxicol Pharmacol 66(2):208-216; doi: 10.1016/j.yrtph.2013.03.010.

Rowlands JC, Budinsky R, Gollapudi B, Black MB, Wolfinger RD, Cukovic D, Bombkowski A, Thompson CM, Urban JD, Thomas RS. 2013. A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes. Toxicol Sci 136(2):595-604; doi: 10.1093/toxsci/kft203.