Professional Profile
Ms. Morgan Jacobellis is a toxicologist in ToxStrategies’ Health Sciences practice with expertise that supports human health and ecological risk assessment projects. Her work includes conducting systematic and targeted literature reviews, evaluating toxicological evidence, and supporting the development of regulatory, product-related, litigation, and environmental assessments. She has supported chemical exposure hazard identification and mechanistic evaluations, with experience integrating toxicological, epidemiological, and mechanistic evidence. Ms. Jacobellis has evaluated scientific literature to support regulatory assessments, including research examining potential relationships between ultra-processed foods (UPFs) and adverse health outcomes. In this work, she has characterized the scientific and regulatory landscape by developing and executing structured literature search strategies and evidence reviews across multiple scientific databases and regulatory agency websites.
Ms. Jacobellis earned her M.S. in Environmental Toxicology from Clemson University. Her thesis research investigated the effects of an epidemiologically derived mixture of persistent organic pollutants on metabolic health, particularly affecting childhood birthweight. She evaluated environmentally relevant chemical mixtures using in vitro systems and incorporated mechanistic components relevant to adverse outcome pathway (AOP) development, including key events associated with metabolic disruption. She has experience using mammalian in vitro models to evaluate the effects of environmentally relevant chemical mixtures on metabolic health. She has performed cell viability assays, transactivation reporter assays for the PPAR nuclear receptor family, and Mitochondrial Stress Tests, and has evaluated metabolic pathway effects HepG2 (hepatic) and C2C12 (skeletal muscle) cells.
Ms. Jacobellis also has experience using in vivo ecological models to examine herbicide exposure effects on invertebrate behavior and regeneration endpoints. She is proficient in bioinformatics and computational biology tools such as Blast, Phytozome, Cytoscape, PaperBlast, EFI Enzyme Similarity Tool, Muscle, UniPort, and iTol, which she has used to support sequence analysis, functional annotations, and biological dataset interpretation.
Ms. Jacobellis also has experience conducting human-centered research assessing consumer perceptions and responses. She has supported structured observational research examining participant reactions, where she contributed to characterizing behavioral responses. Additionally, she has used statistical analysis programs such as StatPlus and GraphPad Prism to analyze and visualize data sets. Ms. Jacobellis has presented her research at regional and national scientific meetings, has reported her results in peer-reviewed journals, and has facilitated lectures and discussions for biology and environmental sustainability undergraduate courses.