Professional Profile
Dr. Grace Patlewicz is a Computational Toxicologist specializing in mammalian toxicity with industrial and regulatory experience in North America and Europe. Dr. Patlewicz has led innovative research programs for developing and applying computational chemistry to identify chemical features associated with specific biological interactions or modes of action, enabling prediction of specific toxicity manifestations of environmental and industrial chemicals. Dr. Patlewicz also leverages computational chemistry principles to develop tools that chemical regulators, researchers, and practitioners can use as adjuncts to modes of action in risk assessment, as well as to weigh the hazard, pharmacokinetic, and exposure-related properties of new and legacy chemicals.
Dr. Patlewicz’s research interests have focused on developing and applying (Q)SARs and read-across for regulatory purposes. She has chaired various industry groups and has contributed to technical guidance for (Q)SARs, chemical categories, and Adverse Outcome Pathways (AOPs) under various Organisation for Economic Co-operation and Development (OECD) work programs. Before joining ToxStrategies, Dr. Patlewicz started her toxicology career at Unilever United Kingdom before moving to the European Commission Joint Research Centre in Italy and then to DuPont and the Environmental Protection Agency (EPA) in the United States. She is an Adjunct Professor in the Department of Environmental Sciences and Engineering (ESE) at the University of North Carolina (UNC), Chapel Hill. She has published extensively in the peer-reviewed literature and has presented nationally and internationally at scientific conferences and meetings.