Professional Profile
Dr. Matthew Wheeler is a Senior Science Advisor in ToxStrategies’ Health Sciences practice. He specializes in machine learning and statistical methods, focusing on toxicology data. With over twenty years of experience as a biostatistician in the health sciences field, Dr. Wheeler’s expertise involves analyzing large data sets requiring extensive computational resources. He is an internationally recognized expert in dose-response risk assessment, and his work is used by the U.S. Environmental Protection Agency, (EPA) Health Canada, the World Health Organization (WHO), and the European Food Safety Authority (EFSA), among others, to perform chemical risk assessments. He was awarded the Presidential Early Career Award for Scientists and Engineers for his work. Additionally, his experience includes developing novel statistical methods related to chemical and non-chemical risk assessments; he has most recently developed biological pathway-based techniques for transcriptomic points of departure. His software is central to BMD Express 3.0 and the EPA’s benchmark dose online platform.
To perform complex data and statistical analyses, Dr. Wheeler uses his expertise in statistics and machine learning algorithms to develop efficient computational approaches. He focuses on developing software that allows other scientists to utilize these approaches, enabling translational dissemination and transparency.
Before joining ToxStrategies, Dr. Wheeler served as a Staff Scientist at the National Institute of Environmental Health Sciences (NIEHS), as a Statistician at the National Institute for Occupational Safety and Health (NIOSH), and as a Health Statistician at the Centers for Disease Control (CDC).