Two toxicologists from ToxStrategies’ Pharmaceuticals Practice are among the team with a new publication concerning the use of in silico (computer modeling) approaches in assessing cancer hazards. Drs. Doug Keller and Amy Mihalchik collaborated with a multi-disciplinary group of scientists to publish a case study of an in silico approach to assess pregabalin, which is carcinogenic to mice. The team’s work demonstrates the need for development of reliable in silico models to predict nongenotoxic compound carcinogenicity, as part of the scientific community’s ongoing effort to move this type of research away from dependence on animal data. The article appears in Frontiers in Toxicology.