Publication Topic

Covington TR, Teeguarden J, Sarangapani R, Gentry PR, Clewell HJ. Evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry. Presentation at the Annual Society for Risk Analysis Conference, Seattle, WA, December 2001.

Clewell HJ, Gentry PR, Gearhart JM, Covington TR, Banton MI, Andersen ME. 2001. Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone. Toxicol Sci 63:160–172.

McMillan DA, Walden GL, Buchanan W. Peroxide degradation kinetics during use of Crest Whitestrips. J Dent Res 80(173), 2001.

McMillan DA, Gibb RD, Gerlach RW. Impact of increasing hydrogen peroxide concentration on bleaching strip efficacy and tolerability. J Dent Res 80:173, 2001.

Lau C, Mole ML, Copeland FM, Rogers JM, Kavlock RJ, Shuey DL, Cameron AM, Ellis DH, Logsdon TR, Merriman J, Setzer RW. 2001. Toward a biologically-based dose-response model for the developmental toxicity of 5-fluorouracil in the rat: Acquisition of experimental data. Toxicol Sci 59:37–48.

Setzer RW, Lau C, Mole ML, Copeland FM, Rogers JM, Kavlock RJ. 2001. Toward a biologically-based dose-response model for the developmental toxicity of 5-fluorouracil in the rat: A mathematical construct. Toxicol Sci 59:49–58.

Rogers JM, Hunter ES III. 2001. Toxicological highlight. Redox redux: A closer look at conceptual low molecular weight thiols. Toxicol Sci 62:1–3.

Huang Y-S, Held G, Andrews JE, Rogers JM. 2001. 14C-Methanol incorporation into DNA and specific proteins of organogenesis-stage mouse embryos in vitro. Reprod Toxicol 15:429–435.

Leazer TM, Rogers JM. 2001. Role of the acute phase response and tissue necrosis factor alpha in the developmental toxicity of lipopolysaccharide in the CD-1 mouse. Reprod Toxicol 16:173–179.

Lea IA, Sivashanmugam P, O’Rand MG. 2001. Zonadhesin: Characterization, localization, and zona pellucida binding. Biol Reprod 65(6):1691–700.

Shipp AM, Gentry PR, Lawrence G, Van Landingham C, Covington T, Clewell HJ, Gribben K, Crump K. 2000. Determination of a site-specific reference dose for methylmercury for fish-eating populations. Toxicol Ind Health 16(9-10):335–438.

Andersen ME, Sarangapani R, Gentry PR, Clewell HJ, Covington TR, Frederick CB. 2000. Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: An example with acrylic acid. Toxicol Sci 57:312–325.

Sagel PA, Odioso LL, McMillan DA, Gerlach RW. 2000. Vital tooth whitening with a novel hydrogen peroxide strip system: Design, kinetics, and clinical response. Comp Cont Educ Dent 21(Suppl. 29):10–15.

Jankowski-Hennig MA, Clegg MS, Daston GP, Rogers JM, Keen CL. 2000. Zinc-deficient rat embryos have increased caspase 3-like activity and apoptosis. Biochem Biophys Res Commun 271:250–256.

Lau C, Anderson ME, Crawford-Brown DJ, Kavlock RJ, Kimmel CA, Knudsen TB, Muneoka K, Rogers JM, Setzer RW, Smith G, Tyl R. 2000. Evaluation of biologically based dose-response modeling for developmental toxicity: A workshop report. Regul Toxicol Pharmacol 31:190–199.

Clewell HJ III, Gentry PR, Allen BC, Covington TR, Gearhart JM. 2000. Development of a physiologically-based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment. Environ Health Perspect 108(Suppl 2):283–305.

Gentry R, Clewell H, Covington T, Wilson J. Investigation of the impact of Benchmark and PBPK modeling on the derivation of MRLs. Poster presented at the Society of Toxicology Annual Meeting, Philadelphia, PA, March 2000.

Clewell HJ, Gentry PR, Gearhart JM, Born SL, Lehman-McKeeman LD, Covington TR. Development of a physiologically-based pharmacokinetic (PB-PK) model and human health risk assessment for coumarin.  Poster presented at the Society of Toxicology Annual Meeting, Philadelphia, PA, March 2000.

Choksi NY, Nix WB, Wyrick SD, Booth RG. 2000. A novel phenylaminotetralin (PAT) recognizes histamine H1 receptors and stimulates dopamine synthesis in vivo in rat brain. Brain Research 852:151–160, DOI: 10.1016/s0006-8993(99)02228-3.

Choksi NY, Nix WB, Wyrick SD, Booth RG. Phenylaminotetralins activate histamine H1 receptors to stimulate dopamine synthesis in vivo in rat brain. Poster presented at the Receptor Chemistry Towards the Third Millennium – 12th Camerino-Noordwijkerhout Symposium, 1999.