Publication Topic

Gentry R, Greene T, Chappell G, Lea I, Borghoff S, Yang C, Rathman J, Ribeiro JV, Hobocienski B, Mostrag A, Rodricks J, Clewell H. 2021. Integration of evidence to evaluate the potential for neurobehavioral effects following exposure to USFDA-approved food colors. Food Chem Toxicol 151:112097. doi: 10.1016/j.fct.2021.112097. Epub 2021 Mar 4. PMID: 33677041.

Lea IA, Chappell GA, Wikoff DS. 2021. Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence. Mutat Res Genet Toxicol Environ Mutagen 868–869:503389. doi: 10.1016/j.mrgentox.2021.503389. PMID: 34454695.

Heintz MM, Doepker CL, Wikoff DS, Hawks SE. 2021. Assessing the food safety risk of ochratoxin A in coffee: A toxicology-based approach to food safety planning. J Food Sci (open access).

Barnett LMA, Kramer NE, Buerger AN, Love DH, Bisesi JH, Cummings BS. 2021. Transcriptomic analysis of the differential nephrotoxicity of diverse brominated flame retardants in rat and human renal cells. Int J Mol Sci 22(18):10044.

Crincoli CM, van de Ligt JLG, Pavel AT, Eapen AK. 2021. A decision tree supporting the use of regulatory frameworks in food ingredient safety: An industry perspective. American College of Toxicology 42nd Annual Meeting.

East A, Isaacs K, Vallero D. Application of the Residential Population Generator (RPGen) in prediction of exposure outcomes for owners and renters from consumer products using the Combined Human Exposure Model (CHEM). Symposium presented at International Society of Exposure Science Annual Meeting, virtual conference, September 2021, DOI: 10.23645/epacomptox.16632319, open access online.

East A, Brady S, Isaacs K, Vallero D. The role of the Product Use Scheduler (PUS) in determining product use categories (PUCs) for owners and renters in the Combined Human Exposure Model (CHEM). Symposium presented at International Society of Exposure Science Annual Meeting, virtual conference, September 2021. DOI: 10.23645/epacomptox.16632271, open access online.

Fisher H, East A, Vallero D. Estimating longitudinal aggregate exposure — The third module of CHEM: Source to dose. Symposium presented at International Society of Exposure Science Annual Meeting, virtual conference, September 2021, DOI: 10.23645/epacomptox.16630675, open access online.

East A, Dawson D, Glen G, Isaacs K, Dionisio K, Price PS, et al. 2021. The Residential Population Generator (RPGen): Parameterization of residential, demographic, and physiological data to model intraindividual exposure, dose, and risk. Toxics 9(11):303, DOI: 10.3390/toxics9110303, open access online.

Wikoff D, Fitch S, Borghoff S. Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff):  61^st Annual Meeting (virtual) of the Society for Birth Defects Research & Prevention, June 2021.

Parker JA, Boles C, Buerger AN, Fung ES, Maier A. 2021. Derivation of an occupational exposure limit for β-glucans. Regul Toxicol Pharmacol 123:104959.

Fitch SE, Payne LE, van de Ligt JLG, Doepker C, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Public Health 21(1):956, doi: 10.1186/s12889-021-10934-2.

Borghoff SJ, Fitch SE, Black MVB, McMullen PD, Andersen ME, Chappell GA. 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124:104977; DOI: 10.1016/j.yrtph.2021.104977.

Proctor DM, Bhat V, Suh M, Reichert H, Jiang X, Thompson CM. 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124:104969, doi.org/10.1016/j.yrtph.2021.104969.

Wikoff D. The [acceptable daily intake] for low- and no-calorie sweeteners: Origin, interpretation, and application. Invited speaker: Continuing education webinar, Institute for the Advancement of Food and Nutrition Sciences, July 2021.

Ring C, Sipes NS, Hsieh JH, Carberry C, Koval LE, Klaren WD, Harris MA, Auerbach SS, Rager JE. 2021. Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high throughput toxicokinetics. Comput Toxicol 18:100166, PMID: 34013136.

Rivera BN, Rohlman D, Anderson K, Tilton S. Chemical mixtures: What we know and where the field is headed. Northwest Toxics Community Coalition Virtual Summit, April 2021.

Rooney JP, Choksi NY, Ceger P, Daniel AB, Truax J, Allen D, Kleinstreuer N 2021. Analysis of variability in in vivo rabbit skin irritation assay results. Regul Toxicol Pharmacol 122:104920, DOI: 10.1016/j.yrtph.2021.104920.