Publication Topic

Pecquet AM, Martinez JM, Vincent M, Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878, doi: 10.1002/jat.3594.

Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ, et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415, doi: 10.1080/10408444.2018.1430121.

Choksi N, Daniel A, Lebrun S, Nguyen M, DeGeorge G, Willoughby JA, et al. Performance of the OptiSafe ocular irritation assay in a three-laboratory validation study. Poster presented at Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.

Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer … Choksi N, et al. 2018. In vitro to in vivo extrapolation for high throughput prioritization and decision making. Toxicol In Vitro 47:213–227, DOI: 10.1016/j.tiv.2017.11.016

Buerger AN, Martyniuk CJ, Bisesi JH. Phthalate disruption of the gastrointestinal microbiome as a potential obesogenic mechanism: A multigenerational study using Danio rerio. Society of Toxicology Meeting, 2018.

Buerger AN, Dillon DT, Martyniuk CJ, Bisesi JH. Host-microbiome alterations in fatty acid metabolism in Danio rerio following dietary phthalate exposure. Society of Environmental Toxicology and Chemistry North America Meeting, 2018.

Zhou W, Pal AS, Hsu AY, Gurol T, Zhu X, Wirbisky-Hershberger SE, Freeman JL, Kasinski AL, Deng Q. 2018. MicroRNA-223 supresses the canonical NF-kB pathway basal keratinocytes to dampen neutrophilic inflammation. Cell Reprod 13:1810–1823.

Wikoff D, Urban JD, Harvey S, Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol, DOI: 0.1177/1091581818754330.

Mihalchik AL, Rogers EN. 2018. Classes of compounds with GI tract toxicity. Chapter 13 in: Gad SC (ed), Toxicology of the Gastrointestinal Tract. CRC Press.

Doepker C, Franke K, Myers E, Goldberger JJ, Lieberman HR, O’Brien C, Peck J, Tenenbein M, Weaver C, Wikoff D. 2018. Key findings and implications of a recent systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Nutrients 10:1536, doi: 10.3390/nu10101536.

Wirbisky-Hershberger SE, Sanchez OF, Horzmann KA, Thanki D, Yuan C, Freeman JL. 2017. Atrazine exposure decreases the activity of DNMTs, global DNA methylation levels, and dnmt expression. Food Chem Toxicol 109:727–734.

Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C, Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; DOI: 10.1021/acs.chemrestox.7b00221.

McMillan DA, Kosemund K, Mahony C, Huber M, Bowtell P. Threshold of toxicological concern (TTC) for botanicals—Data analysis to substantiate and extend the TTC approach to botanicals. In: The Toxicologist: Suppl to Toxicol Sci 156(1), Abstract no. 1831, Society of Toxicology, 2017.

Sheppard A, Baker E, Bermudez D, Blattner J, Boyd K, O’Neal S, Rahim T, Whittle E. Implementing an alternate testing strategy for assessing skin irritation. Society of Toxicology, Abstract #2734, Baltimore, MD, 2017.

Sheppard A, Baker E, Bermudez D, Blattner J, Boyd K, O’Neal S, Rahim T, Whittle E. Use of alternative methods to assess skin irritation of chemical mixtures. World Congress for Alternatives to Animal Testing, Seattle, WA, 2017.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB Is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology Annual Meeting, Baltimore, Md, and NIEHS Environmental Health Science FEST, Durham, NC, 2017.

Iwata Y, Klaren W, Grimm F, Rusyn I. A multidimensional high-throughput approach for toxicity evaluation of environmental chemicals in induced pluripotent stem cell-derived endothelial cells. Society of Toxicology Annual Meeting, Baltimore, Md, 2017.

Iwata Y, Klaren WD, Lebakken CS, Grimm FA, Rusyn I. 2017. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay Drug Dev Technol 15(6):267–279, PMID: 28771372.

Garabrant D, Pastula S. Asbestos and EMP fiber potency analysis. Abstract, Oral Presentation, Monticello Conference, Charlottesville, VA, October 2017.