Publication Topic

Borghoff SJ, Fitch S, Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99(Nov):168–181; doi: 10.1016/j.yrtph.2018.09.001.

Ring CL, Suh M, Casteel S, Dunsmore M, Verwiel A, Proctor D. Relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.

Harrill AH, Borghoff S, Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ. 2018. NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies. National Toxicology Program Research Report 6, Research Triangle Park, NC.

Chowdhary P, Vivanco SN, Kelly C, Leiga A. What’s in your laundry detergent? An evaluation of common surfactants found in laundry detergents and their PBT characteristics. Presentation to Society of Environmental Toxicology and Chemistry, November 2018.

Vivanco SN, Chowdhary P, Kelly C. Evaluating Prop 65 exposure to ethylene oxide and 1,4-dioxane in personal care products. Presentation to Society of Environmental Toxicology and Chemistry, November 2018.

Casey WM, Chang X, Allen DG, Ceger PC, Choksi NY, Hsieh JH, et al. 2018. Evaluation and optimization of pharmacokinetic models for in vitro to in vivo extrapolation of estrogenic activity for environmental chemicals. Environ Health Perspect 126(9):97001; doi: 10.1289/EHP1655.

Wikoff DS, Thompson C, Rager J, Chappell G, Fitch S, Doepker C. 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120:709-723; doi: 10.1016/j.fct.2018.08.031.

Covington TR, Ott DK, Gearhart JM, Pangburn HA. A physiologically-based pharmacokinetic model to address physiological changes associated with high-performance aircraft flight. Presentation at the Annual Meeting of the Military Health System Research Symposium, Orlando, FL, August 2018.

Adamovsky O, Buerger AN, Wormington AM, Ector N, Griffitt RJ, Bisesi JH, et al. 2018. The gut microbiome and aquatic toxicology: An emerging concept for environmental health. Environ Toxicol Chem 37(11):2758–2775.

Benson SM, Maskrey JR, Nembhard M, Panko JM. Characterization of surgical smoke generated from electrocautery instruments: A pilot study. Poster at the 2018 American Occupational Health Conference (AOHC) 103rd Annual Meeting, New Orleans, LA, April 29 – May 2, 2018.

Grimm FA, Klaren WD, Li X, House JS, Chiu W, Lehmler HJ, Robertson LW, Rusyn I. Cardiotoxicity screening of polychlorinated biphenyls and their major metabolites. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.

Klaren WD, Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.

Wikoff D, Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Borghoff S, Wikoff D, Urban JD, Rager JE. A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Klaren WD, Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342; doi: 10.1089/adt.2018.86. PMID: 30070899.

Powles MA, Galgoci A, Misura A, Colwell L, Dingley K, Tang W, et al. 2018. In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models. Antimicrob Agents Chemother 62:e02577–17; doi: 10.1128/AAC.02577-17. PMID: 29866878.

Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, … Dingley KH, et al. 2018. Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists. ACS Med Chem Lett (9):1088–1093; doi: 10.1021/acsmedchemlett.8b00306. PMID: 30429950.

Fung ES, Unice KM, Paustenbach DJ, Finley BL, Kovochich M. 2018. Methods for sterilizing clinically relevant wear particles isolated from metal-on-metal hip implants. Sci Rep 8(1):2384.

Kovochich M, Finley BL, Novick R, Monnot AD, Donovan E, Unice KM, Fung ES, Fung D, Paustenbach DJ. 2018. Understanding outcomes and toxicological aspects of second-generation metal-on-metal hip implants: A state-of-the-art review. Crit Rev Toxicol 48(10):839–887.

Heintz MM, Kumar R, Baldwin WS. Cyp2b-null male mice are susceptible to high-fat diet-induced obesity due to changes in PUFA metabolism and response to hepatic lipids as measured by RNAseq. American College of Toxicology, 39th Annual Meeting, West Palm Beach, FL, November 2018.