In 2020, scientists at the University of Washington-Tacoma and Washington State University identified a chemical that causes pre-spawn mortality in coho salmon: 6PPD-quinone. 6PPD-quinone is a transformation product of 6PPD, an antiozonant used in tires. Currently, 6PPD is used in all tires, is found in recycled tire products, and can contaminate stormwater anywhere tires are used. A team of the nation’s leading experts, formed under the Interstate Technology & Regulatory Council (ITRC) as the Tire Anti-Degradants (6PPD) Team, was assembled in early 2023 to advance the science and provide education and guidance on the emerging contaminant of concern, 6PPD-quinone, and its parent compound, 6PPD. Based on the acute toxicity to coho salmon and the rapidly emerging science, the team aims to provide timely guidance to federal, state, and tribal governments that manage or regulate water quality, toxics, solid waste, fish and wildlife, and transportation. The team’s second product, a guidance document with anticipated issuance 9/2024, presents the latest science on toxicity, fate and transport, and assessment and mitigation strategies for 6PPD and 6PPD-quinone. The ITRC 6PPD Team will present a poster that will utilize the ITRC’s 6PPD and 6PPD-quinone guidance document to 1) promote awareness of the rapidly emerging contaminants 6PPD and 6PPD-quinone, and 2) provide the latest innovations regarding stormwater best management practices, alternative chemical assessments to eliminate or reduce 6PPD and 6PPD-quinone, research to determine toxicological mechanisms within organisms, cutting edge guidance on monitoring and analytical methods for measuring these chemicals in water and aquatic organisms, and current research efforts and projected next steps to finding a solution to 6PPD and 6PPD-quinone.