2017 (10 POSTS)
Kirman CR, Proctor D, Suh M, Haws L, Harris M, Thompson C , Hays S. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
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Topics: chromium , modeling , pharmacokinetics
Thompson C , Kirman C, Suh M, Proctor D, Haws L , Harris M, Hays S. 2017. Risk assessment of oral exposure to Cr(VI): Integration of mode of action, pharmacokinetics, and dose-response modeling. Poster presented at Society of Toxicology Annual Meeting, March 14, Baltimore, MD.
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Topics: chromium , risk assessment
Suh M, Harvey S, Wikoff D, Mittal L, Ring C, Goodmanson A, Proctor D . Meta-analysis of hexavalent chromium and stomach cancer. Poster presented at Society of Toxicology 56th Annual Meeting, March 13, Baltimore, MD, March 2017.
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Topics: Cancer , chromium , meta-analysis
Thompson CM , Wolf, JC, McCoy A, Suh M , Proctor DM , Kirman CR, Haws LC , Harris MA. 2017. Comparison of toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens captan, folpet, and hexavalent chromium. Toxicol Pathol 45(8):1091–1101; doi: 10.1177/019262331yy432 4.
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Topics: carcinogens , chromium
2016 (12 POSTS)
Thompson CM , Bichteler A, Rager JE, Suh M , Proctor DM , Haws LC , Harris MA. 2016. Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium. Mut Res/Genet Toxicol Environ Mutagen 800-801(April):28-34; doi: 10.1016/j.mrgentox.2016.01.008 .
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Topics: carcinogens , chromium , mode of action
Wikoff D, Suh M, Harvey S, Proctor D , Beretvas T, Goodman M, Lipworth L. 2016. Systematic review and meta-analysis of occupational exposure to Cr(VI) and stomach cancer. PROSPERO 2016:CRD42016051625 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016051625
Topics: Cancer , chromium , meta-analysis , Occupational , Systematic Review
Thompson CM , Rager JE, Suh M , Ring CL, Proctor DM , Haws LC , Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57(9):706-716; doi: 10.1002/em.22064 .
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Topics: chromium , risk assessment , transcriptomics
De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M , Proctor DM . 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. I. Chemical reduction and mitigation of mutagenicity. Toxicol Appl Pharmaco l 306(Sept 1):113-119; doi: 10.1016/j.taap.2016.07.004 .
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Topics: chromium
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM . 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80(Oct):60-70; doi: 10.1016/j.yrtph.2016.05.031 .
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Topics: Air Quality , Systematic Review , titanium dioxide
Suh M , Thompson CM , Brorby GP , Mittal L , Proctor DM . 2016. Inhalation cancer risk assessment of cobalt metal. Regul Toxicol Pharm 79(Aug):74-82; doi: 10.1016/j.yrtph.2016.05.009 .
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Topics: Cancer , cobalt , Metals , risk assessment
Kirman CR, Suh M , Hays SM, Gürleyük H, Gerads R, De Flora S, Parker W, Lin S, Haws LC , Harris MA, Proctor DM . 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling. Toxicol Appl Pharmacol 306:120-133.
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Topics: chromium
Proctor DM . Cancer risk assessment for ingested hexavalent chromium: Challenges and controversies – Introduction. [session introduction; no abstract]. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
Topics: Cancer , chromium , risk assessment
Thompson CM , Suh M , Proctor DM , Rager JE, Haws LC , Harris MA. Assessment of the in vivo genotoxicity of CrVI in target organs identified in a two-year cancer bioassay. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: chromium , genotoxicity
Suh M , Crump K, Mittal L , Hirsch S, Valdes Salgado R, Bartlett C, Van Landingham C, Rohr A, Proctor DM . Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: Cancer , chromium , Exposure Assessment , risk assessment
Brorby GP , Suh M , Thompson CM , Mittal L , Proctor DM . Inhalation cancer risk assessment of cobalt metal. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: Cancer , cobalt , Metals , risk assessment
Verwiel A , Proctor D , Tachovsky A. 2016. Principal component analysis of metals in soil and dust to distinguish background and anthropogenic sources in an urban area. Association for Environmental Health and Sciences Foundation Annual Meeting, San Diego, CA, March 2016.
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Topics: Metals
2015 (11 POSTS)
Proctor DM , Suh M , Mittal L , Hirsch S, Salgado RV, Bartlett C, Van Landingham C, Rohr A, Crump K. 2015. Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. J Expo Sci Environ Epidemiol 26(2):224-231. doi: 10.1038/jes.2015.77 .
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Topics: Cancer , chromium , risk assessment
Kirman CR, Proctor DM , Suh M , Hays S. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: chromium , modeling , toxicokinetics
Suh M , Mittal L , Hirsch S, Valdes R, Bartlett C, Rohr A, Proctor D. 2015. Lung cancer risk in chromate production workers exposed to hexavalent chromium. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: Cancer , chromium , Occupational
Proctor D , Suh M , Thompson C , Hixon, G. Inhalation cancer risk assessment of titanium dioxide. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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