2020 (12 POSTS)
Whaley P, Aiassa E, Beausoleil C, Beronius A, Bilotta, G, Boobis A, de Vries R, Hanberg A, Hoffman S, Hunt N, Kwiatkowski CF, Lam J, Lipworth S, Martin O, Randall, N, Rhomberg L, Rooney AA, Holger J, Schünemann HJ, Wikoff D , Wolffe T, Halsall C. 2020. Recommendations for the conduct of systematic reviews in toxicology and environmental health research (COSTER). Environ Int 143:105926.
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Topics: Systematic Review
Urban JD , Wikoff DS , Chappell GA, Harris C, Haws LC . 2020. Systematic evaluation of mechanistic data in assessing in utero exposures to trichloroethylene and development of congenital heart defects. Toxicology 436(30 April):152427; doi: 10.1016/j.tox.2020.152427 . PMID: 32145346.
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Topics: trichloroethylene
Chappell GA, Wikoff DS , Doepker CL , Borghoff SJ . 2020. Lack of potential carcinogenicity for acesulfame potassium — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 141(July):111375; doi: 10.1016/j.fct.2020.111375 .
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Topics: carcinogens , Systematic Review
Henderson RG , Franzen A , Franke K , Payne L, Schmitt D , Wikoff D . Creating a literature database for cannabidiol (CBD): Systematic evidence mapping. Poster for Society of Toxicology 59th Annual Meeting, Virtual, 2020.
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Topics: Cannabinoid/Industrial Hemp , Epidemiology , Systematic Review
Ring C, Fitch S , Haws L , Harris M, Wikoff D . Quantitative integration of dose-response data for relative potency estimates of dioxin-like chemicals. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Topics: dioxin
Wikoff D , Franzen A , Chappell G, Harris M, Thompson C . Systematic characterization of hexavalent chromium and potential female reproductive outcomes: Application of US EPA critical appraisal tools and stepwise inclusion of mechanistic data. Poster for Society of Toxicology , Society of Toxicology 59th Annual Meeting, Virtual, 2020.
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Topics: chromium
Wikoff DS , Bennett DC, Brorby GP , Franke KS . 2020. Evaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth. Food Addit Contam A 37(5):804-814; doi: 10.1080/19440049.2020.1727963 . PMID: 32134694.
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Topics: food safety , Food science , risk assessment
Lalu M, Jeffers M, Moher D, Sena E, Macleod MR, Avey M,… Wikoff D . 2020. PRISMA extension for preclinical in vivo animal experiments. OSF | PRISMA Extension for Preclinical In Vivo Animal Experiments .
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Topics: Systematic Review
Chappell GA, Borghoff SJ , Pham L, Doepker CL , Wikoff DS . 2020. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135(Jan):110898; doi: 10.1016/j.fct.2019.110898 .
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Topics: Systematic Review
Wikoff DS , Chappell GA, Fitch S , Doepker CL , Borghoff SJ . 2020. Lack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135(Jan):110866; doi: 10.1016/j.fct.2019.110866 .
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Topics: carcinogens , food additives , food safety , Food science , Systematic Review
2019 (13 POSTS)
Fitch S , Goyak K, Green M, Grimm F, Wikoff D . 2019. Estrogen-mediated outcomes for alkylphenols via an adverse outcome pathway (AOP) construct. Open Science Framework , August.
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Topics: Systematic Review
Fitch S , van de Ligt J, Payne L, Doepker C , Kleinman R, Handu D, Cohen SM, Anyangwe N, Wikoff D . 2019. Systematic map protocol: A systematic map of the use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS). Open Science Framework .
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Topics: nutrition , Systematic Review
Wikoff D , Haws L , Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol 39(9):1293-1310; doi: 10.1002/jat.3814 .
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Topics: dioxin , risk assessment
Wikoff D , Erranguntla N, Lewis J, Foreman J. A fit-for-purpose framework for use of systematic methods in risk assessment. Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.
Topics: risk assessment , Systematic Review
Urban J , Wikoff D , Haws L . Three-tiered approach to integrating evidence streams assessing gestational trichloroethylene exposure and congenital heart defects (TCE-CHD). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine. Washington, DC, June 2019.
Topics: Toxicology
Borghoff S , Fitch S , Britt J , Franke K , Wikoff D . Application of the EFSA/ECHA endocrine disruption guidance as a framework for evidence integration in a weight-of-evidence (WoE) analysis for oxybenzone (BP-3). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.
Topics: chemical safety assessment , risk assessment
Wikoff D . Rigor and resources for systematic reviews in toxicology: Case study applications in food safety, consumer product safety, and environmental health risk assessment. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.
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Topics: Systematic Review
Urban J , Wikoff D , Suh M , Britt J , Harvey S , Chappell G, Haws L . Comparison of NTP OHAT and US EPA TSCA study quality criteria: Trichloroethylene (TCE) and congenital heart defects (CHDs) as a case study. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.
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Topics: Toxicology
Borghoff SJ , Fitch S , Huggett, Wikoff D . A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA). 2019. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.
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Topics: PFAS
Ring CL, Urban J , Wikoff D , Thompson C , Budinsky RA, Haws LC . Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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