2023 (60 POSTS)
Patlewicz G , Shah I. 2023. Towards systematic read-across using Generalized Read-Across (GenRA). Comput Toxicol 25(Feb):100258; doi: 10.1016/j.comtox.2022.100258 . PMID: 37693774.
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Topics: NAMs
Houck K, Paul Friedman K, Feshuk M, Patlewicz G , Smeltz M, Clifton S, Wetmore BA, Velichko S, et al. 2023. Evaluation of 147 perfluoroalkyl substances for immunotoxic and other (patho)physiological activities through phenotypic screening of human primary cells. ALTEX 40(2):248–270; doi: 10.14573/altex.220304 . PMID: 36129398.
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Topics: chemical safety assessment , PFAS
Adams M, Hilde H, Chang D, Richard A, Williams AJ, Shah I, Patlewicz G . 2023. Development of a CSRML version of the Analog Identification Methodology (AIM) fragments and their evaluation within the Generalized Read-Across (GenRA) approach. Comput Toxicol 25(Feb):100256; doi: 10.1016/j.comtox.2022.100256 . PMID: 36733411.
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Topics: NAMs
Wheeler MW , Lim S, House JS, Shockley KR, Bailer AJ, Fostel J, Yang L, Talley D, Raghuraman A, Gift JS. 2023. ToxicR: A computational platform in R for computational toxicology and dose–response analyses. Comp Toxicol 25(Feb):100259; doi: 10.1016/j.comtox.2022.100259 . PMCID: PMC9997717.
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Topics: benchmark dose estimation (BMD)
East A , Dawson DE, Brady S, Vallero DA, Tornero-Velez R. 2023. A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models. Toxics 11(2):163; doi: 10.3390/toxics11020163 . PMID: 36851038.
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Topics: modeling , PFAS , scoping review , toxicokinetics
Grover A, Sankaranarayanan S, Mathur V, Suri P, Qiu H, Andrews-Zwilling Y, Mease K , Taylor LK, Cahir-McFarland E, Keswani S, Yednock T. 2023. Pharmacokinetic and target engagement measures of ANX007, an anti-C1q antibody fragment, following intravitreal administration in nonhuman primates. Invest Opthalmol Visual Sci 64(2)3; 10.1167/iovs.64.2.3 . PMID: 36729444.
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Topics: pharmacokinetics
Boyce M, Favela KA, Bonzo JA, Chao A, Lizarraga L, Moody LR, Owens EO, Patlewicz G , et al. 2023. Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis. Front Toxicol 5(Jan 18):1051483; doi: 10.3389/ftox.2023.1051483 . PMID: 36742129.
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Topics: spectrometry
Lizarraga L, Suter GW, Lambert JC, Patlewicz G , Zhao JQ, Dean JL, Kaiser P. 2023. Advancing the science of a read-across framework for evaluation of data poor chemicals incorporating systematic and new approach methods. Regul Toxicol Pharm 137(Jan):105293; doi: 10.1016/j.yrtph.2022.105293 . PMID: 36414101.
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Topics: NAMs
Borghoff SJ , Cohen SS, Jiang X , Lea IA , Klaren WD , Chappell GA, Britt JK , Rivera BN , Choksi NY , Wikoff DS . 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549 . PMID: 36493943.
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Topics: carcinogens , food safety , Food science , Systematic Review
Bullano M, Cool C, Schultz BG, Durgapal S, Sacks N , Liu Y , Kee R, Batt K. 2023. Evaluating the financial impact of utilizing recombinant porcine factor VIII or recombinant FVIIa for patients with acquired hemophilia A. Expert Rev Phamacoecon Outcome Res 23(2):225-230; doi: 10.1080/14737167.2023.2160705 . PMID: 36537696.
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Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
2022 (96 POSTS)
Doepker C, Movva N, Cohen SS, Wikoff DS . 2022. Benefit-risk of coffee consumption and all-cause mortality: A systematic review and disability adjusted life year analysis. Food Chem Toxicol 170(Dec):113472; doi: 10.1016/j.fct.2022.113472 . PMID: 36243217.
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Topics: Food science , Systematic Review
Boles C, Zisook R, Buerger AN , Hamaji C, Mathis C, Lauer D, et al. 2022. Semi-quantitative microbial risk assessment: A narrative review and proposed framework for health and safety practitioners. J Pub Health Emerg 6(Dec 25):34; doi: 10.21037/jphe-22-1 .
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Topics: COVID-19 , risk assessment
Broome CM, Hooda N , Su J, Jiang X , Nicholson G, Frankenfeld CL , Iglesias-Rodriguez M, Fryzek J, Patel Parija. 2022. Medically-attended anxiety and depression is increased among newly diagnosed patients with cold agglutinin disease: Analysis of an integrated claim-clinical cohort in the United States. PLoS One 17(12):e0276617; doi: 10.1371/journal.pone.0276617 . PMID: 36520848.
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Topics: Epidemiology
Kato Y, Lim AY, Sakolish C, Valdiviezo A, Moyer HL , Hewitt P, Bajaj P, Han G, Rusyn I. 2022. Analysis of reproducibility and robustness of OrganoPlate® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs. Toxicol in Vitro 85(Dec):105464; doi: 10.1016/j.tiv.2022.105464 . PMID: 36057418.
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Topics: pharmacokinetics
Cardosi L, Rau R, Emdem MR, Kemp R, Minshall M, Pontenani F, Provision S, Sacks N . 2022. Healthcare resource utilization in non-cystic fibrosis bronchiectasis (NCFB) patients with commercial insurance coverage in the US. Value in Health 25(12):S89-S90; doi: 10.1016/j.jval.2022.09.437 .
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Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Godínez-Oviedo A, Sampedro F , Bowman JP, Garcés-Vega FJ, Hernández-Iturriaga M. 2022. Genotypic and phenotypic quantitative microbial risk assessment model of human salmonellosis related to the consumption of chicken meat in the central region of Mexico. Food Res Int 162(A):111901; doi: 10.1016/j.foodres.2022.111901 . PMID: 36461177.
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Topics: food safety , Food science
Shah I, Bundy J, Chambers B, Everett L, Haggard D, Harrill J, Judson R, Nyffeler J, Patlewicz G . 2022. Navigating transcriptomic connectivity mapping workflows to link chemicals with bioactivities. Chem Res Toxicol 35(11):1929-1949; doi: 10.1021/acs.chemrestox.2c00245 . PMID: 36301716.
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Topics: transcriptomics
Yao W, Jensen I , Claussen M, Dandurand K, Buffington B, Fuentes D, Mikhael M. 2022. Health economics of selective early rescue surfactant administration and standard surfactant administration for newborns with respiratory distress syndrome. J Pediatr Pharmacol Ther 27(8):695–702; doi: 10.5863/1551-6776-27.8.695 .
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