2023 (11 POSTS)
Meek ME, Wikoff D . 2023. The need for good practice in the application of mechanistic constructs in hazard and risk assessment. Toxicol Sci 194(1):13-22; doi: 10.1093/toxsci/kfad039 . PMID: 3707944.
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Topics: risk assessment
Choksi NY, Fitch S, Harris MA, Thompson CM , Wikoff DS . Reliability assessment of guideline-based studies using systematic review critical appraisal tools. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Topics: Systematic Review
Thompson CM, Wikoff DS , Proctor DM, Harris MA. An evaluation of risk assessments on hexavalent chromium [Cr(VI)]: The past, present, and future of mode of action research. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Topics: chromium , mode of action , risk assessment
Franzen AC, Thompson CM, Brorby GP , Wikoff DS , Ilkbahar Z, Doepker C . Risk assessment of three smoke flavoring primary products currently under re-evaluation by EFSA. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Topics: food additives , food safety , Food science , risk assessment
Fitch S, Rogers J, Marty S, Ellis-Hutchings R, Becker R, Wikoff D . Development of a study quality tool for use in a systematic review of literature reporting microplastic exposure and reproductive and developmental toxicity. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Topics: microplastics , reproductive toxicology , Systematic Review
Rivera BN, Svetlik A, Klaren WD , Wikoff DS , Henderson RG . Scoping review of the immunomodulatory effects of cannabidiol: Effects within T cells. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Topics: Systematic Review
Borghoff SJ , Cohen SS, Jiang X , Lea IA , Klaren WD , Chappell GA, Britt JK , Rivera BN, Choksi NY , Wikoff DS . 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549 . PMID: 36493943.
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Topics: carcinogens , food safety , Food science , Systematic Review
2022 (5 POSTS)
Doepker C, Movva N, Cohen SS, Wikoff DS . 2022. Benefit-risk of coffee consumption and all-cause mortality: A systematic review and disability adjusted life year analysis. Food Chem Toxicol 170(Dec):113472; doi: 10.1016/j.fct.2022.113472 . PMID: 36243217.
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Topics: Food science , Systematic Review
LaPlaca SB, Heintz MM, Wikoff D, Haws LC . Multi-step integration of ecotoxicological study reliability in ecological risk assessment. Abstract 7.03.P-Th143 , S ociety of Environmental Toxicology and Chemistry (SETAC) North America 43rd Annual Meeting, Philadelphia, PA, November 2022.
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Topics: ecotoxicology , risk assessment
Fitch S, Wikoff D , Britt J, Lea I, Brown L, Borghoff S , et al. 2022. Systematic literature review and critical appraisal of mammalian reproductive studies evaluation potential effects associated with microplastics. OSF | Systematic Literature Review and Critical Appraisal of Mammalian Reproductive Studies Evaluation Potential Effects Associated with Microplastics
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Topics: microplastics , reproductive toxicology , Systematic Review
Fitch S , Klaren WD , LaPlaca S , Payne L, Wikoff D . Comparison of public and private literature databases for toxicological investigations. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.
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Topics: data literacy
Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY… Wikoff D , et al. 2022. Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks. ALTEX 39(3):499-518; doi: 10.14573/altex.2202141 . PMID: 35258090.
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Topics: chemical safety assessment , evidence-based reviews
2021 (16 POSTS)
Franke K , Payne L, Franzen A , Wikoff D , Henderson R . 2021. Cannabidiol literature scoping review protocol. Center for Open Science, OSFHOME (May 20).
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Topics: Cannabinoid/Industrial Hemp , Systematic Review
Fitch S , Goyak KO, Grimm FA, Green ML,
Wikoff D . 2021. Protocol for a Systematic Mapping Review of Estrogen Mediated Outcomes for Alkylphenols via an Adverse Outcome Pathway Construct. Nov. 22, 2021;
https://osf.io/m25nj/files/6rtpq .
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Topics: Systematic Review
Wikoff D , Edwards S, Angrish M,…, Borghoff S ,…, Fitch S ,…, Lea I , Mandel M,…, Urban J , et al. Application of systematic methods to characterize thyroid adverse outcome pathways (AOPs). Presented at 10th annual meeting of American Society for Cellular and Computational Toxicology, Virtual, October 2021.
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Topics: Adverse outcome pathways (AOPs) , Systematic Review
Palermo CM, Foreman JE, Wikoff DS , Lea I . 2021. Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development. Curr Res Toxicol 2(July 22):254–271; doi: 10.1016/j.crtox.2021.07.002 . PMID: 34401750.
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Topics: Adverse outcome pathways (AOPs)
Lea IA , Chappell GA, Wikoff DS . 2021. Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence. Mutat Res Genet Toxicol Environ Mutagen 868–869(Aug-Sept):503389; doi: 10.1016/j.mrgentox.2021.503389 . PMID: 34454695.
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Topics: food safety , Food science , genotoxicity , Systematic Review
Heintz MM , Doepker CL , Wikoff DS , Hawks SE . 2021. Assessing the food safety risk of ochratoxin A in coffee: A toxicology-based approach to food safety planning. J Food Sci 86(11):4799-4810; doi: 10.1111/1750-3841.15938 . PMID: 34642959.
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Topics: food safety
Doepker CD , Heintz MM , van de Ligt JLG, Wikoff DS . 2021. Review of potential risks associated with supplementary dietary exposure to nitrate-containing compounds in swine — A paradox in light of emerging benefits. Trans Anim Sci 5(4):txab203; doi: 10.1093/tas/txab203 . PMID: 34909600.
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Topics: Food science , nutrition
Wikoff D , Fitch S , Borghoff S . Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff): 61st Annual Meeting of the Society for Birth Defects Research & Prevention, Virtual, June 2021.
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