Publication Topic

Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS,…, Patlewicz G, et al. 2023. Evaluation of per- and polyfluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. Chem Res Toxicol 36(3):402–419; doi: 10.1021/acs.chemrestox.2c00344. PMID: 36821828.

Houck K, Paul Friedman K, Feshuk M, Patlewicz G, Smeltz M, Clifton S, Wetmore BA, Velichko S, et al. 2023. Evaluation of 147 perfluoroalkyl substances for immunotoxic and other (patho)physiological activities through phenotypic screening of human primary cells. ALTEX 40(2):248–270; doi: 10.14573/altex.220304. PMID: 36129398.

East A, Dawson DE, Brady S, Vallero DA, Tornero-Velez R. 2023. A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models. Toxics 11(2):163; doi: 10.3390/toxics11020163. PMID: 36851038.

Patlewicz G, Richard AM, Williams AJ, Judson RS, Thomas RS. 2022. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. Comput Toxicol 24(Nov):100250; doi: 10.1016/j.comtox.2022.100250. PMID: 36969381.

Heintz MM, Chappell GA, Thompson CM, Haws LC. 2022. Evaluation of transcriptomic responses in livers of mice exposed to the short-chain PFAS compound HFPO-DA. Front Toxicol 4(Jun 27):937168; doi: 10.3389/ftox.2022.937168. PMID: 35832492.

Patlewicz G, Richard A, Williams A, Judson R, Thomas R. Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing. American Society for Cellular and Computation Toxicology 11^th Annual Meeting, Chapel Hill, NC, October 2022.

Carstens K, Carpenter A, FreudenrichT, Wallace K, Choo S, Patlewicz G, et al. Evaluation of per- and poly fluoroalkyl substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. American Society for Cellular and Computation Toxicology 11^th Annual Meeting, Chapel Hill, NC, October 2022.

Lea IA, Pham LL, Antonijevic T, Thompson C, Borghoff SJ. 2022. Assessment of the applicability of the threshold of toxicological concern for per- and polyfluoroalkyl substances. Regul Toxicol Pharmacol 133(August):105190; doi: 10.1016/j.yrtph.2022.105190. PMID: 35662637.

Carlson LM, Angrish M, Shirke AV, Radke EG, Schulz B, Kraft A, Judson RS, Patlewicz G, et al. 2022. Systematic evidence map for over one hundred and fifty per- and polyfluoroalkyl substances (PFAS). Environ Health Perspect 130(5):56001; doi: 10.1289/EHP10343. PMID: 35580034.

Racz L. PFAS: How did we get here and where are we going? Keynote address at Alliance of Hazardous Materials Professionals national meeting, Las Vegas, NV, March 2022.

Williams AJ, Gaines LG, Grulke CM, Lowe CN, Sinclair G, Samano V, Thillainadarajah I, Meyer B, Patlewicz G, Richard AM. 2022. Assembly and curation of list of per- and polyfluoroalkyl substances (PFAS) to support environmental science research. Front Environ Sci 10(Apr 5):1-13; doi: 10.3389/fenvs.2022.850019. PMID: 35936994.

Hearon SE, Orr AA, Moyer H, Wang M, Tamamis P, Phillips TD. 2022. Montmorillonite clay-based sorbents decrease the bioavailability of per- and polyfluoralkyl substances (PFAS) from soil and their translocation to plants. Environ Res 205(Apr 1):112433; doi: 10.1016/j.envres.2021.112433. PMID: 34875259.

Rogers JM, Heintz MM, Thompson CM, Haws LC. Development of a putative adverse outcome pathway for neonatal mortality in rodents: Implications for human health risk assessments of PFAS. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Richard AM, Hidle H, Patlewicz G, Williams AJ. 2022. Identification of branched and linear forms of PFOA and potential precursors: A user-friendly SMILES structure-based approach. Front Environ Sci 10(Mar 24):865488; doi: 10.3389/fenvs.2022.865488. PMID: 35494535.

Tornero-Velez R, Dawson D, East A, Breen M, Brady S, Vallero D, Hubal EC, Wambaugh, J. Using systematic evidence mapping to track the development of toxicokinetic models of PFAS from 2000–2021. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022; doi: 10.23645/epacomptox.19333283.

Hearon SE, Orr AA, Moyer H, Wang M, Tamamis P, Phillips TD. Montmorillonite clay-based sorbents decrease the bioavailability of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) from soil and their translocation to plants. Abstract 3113, Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Wang Z, Buser A, Cousins I, Demattio S, Drost W, Johansson O, Ohno K, Patlewicz G, et al. 2021. A new OECD definition for per- and polyfluoroalkyl substances. Environ Sci Technol 55(23):15575-15578; doi: 10.1021/acs.est.1c06896. PMID: 34751569.

Houck KA, Patlewicz G, Richard A, Williams AJ, Smeltz M, Clifton, MS, Wetmore B, Medvedev A, Makarov SS. 2021. Bioactivity profiling of per- and polyfluoroalkyl substances identifies potential toxicity pathways related to molecular structure. Toxicology 457(June 15):152789; doi: 10.1016/j.tox.2021.152789. PMID: 33887376.

Kempisty DM, Racz L. 2021. Forever Chemicals: Environmental, Economic, and Social Equity Concerns with PFAS in the Environment. Routledge, Taylor and Francis Group; ISBN 9780367456405.

Chappell GA, Thompson CM, Wolf JC, Cullen JM, Klaunig JE, Haws LC. 2020. Assessment of the mode of action underlying the effects of GenX in mouse liver and implications for assessing human health risks. Toxicol Pathol 48(3):494–508; doi: 10.1177/0192623320905803. PMID: 32138627.