Publication Topic

Cheng H, Orr STM, Bailey S… Liu L, Kath JC. 2021. Structure-based drug design and synthesis of PI3Kα-selective inhibitor (PF-06843195). J Med Chem 64(1):644–661.

Chang Y, Huynh CTT, Bastin KM, Rivera BN, Siddens LK, Tilton SC. 2020. Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures. Toxicol in Vitro 69:104991, doi: 10.1016/j.tiv.2020.104991.

Neier K, Montrose L, Chen K, Malloy M, Jones T, Svoboda L, et al. 2020. Short- and long-term effects of perinatal phthalate exposures on metabolic pathways in the mouse liver. Environ Epigenet 6(1):dvaa017; doi: 10.1093/eep/dvaa017.

Rivera BN, Ghetu C, Adams K, Anderson K, Tilton S. A novel approach to forming sufficiently similar mixtures from environmental exposure data. Pacific Northwest Association of Toxicologists Annual Meeting (virtual), November 2020.

Rivera BN, Ghetu C, Rohlman D, Adams K, Anderson K. A comprehensive comparison of indoor vs outdoor air quality across the United States. Society of Environmental Toxicology and Chemistry, virtual meeting, November 2020.

Bhat VS, Cohen SM, Gordon EB, Wood CE, Cullen JM, Harris MA, Proctor DM, Thompson CM. 2020. An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: A case study with hexavalent chromium, captan, and folpet. Crit Rev Toxicol 50(8) (open access).

Parker J, Boles C, Leleck O, Buerger AN, Egnot N, Sunderman A, et al. 2020. Advancing toward normal operations for arenas and stadiums. Toxicol Ind Health 36(9):718–727.

Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D, Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118:104788.

Fryzek J, Bylsma L, Mease K, Movva N, Welsh BT, Wood M. 2020. Critical insights into nonclinical toxicology and real-world evidence essential for a successful rare disease product launch. EpidStrategies, Inc., white paper.

White Paper

Mahony CA, Bowtell P, Huber M, Kosemund K, Pfuhler S, Zhu T, Barlow S, McMillan DA. 2020. Threshold of toxicological concern (TTC) for botanicals — Concentration data analysis of potentially genotoxic constituents to substantiate and extend the TTC approach to botanicals. Food Chem Toxicol 138:111182.

Mullen KR, Rivera BN, Tidwell AG, Ivanek R, Anderson KA, Ainsworth DM. 2020. Environmental surveillance and adverse neonatal health outcomes in foals born near unconventional natural gas development activity. Sci Tot Environ 732:138497.

Thompson CM, Donahue DA, Hobbs C, Costecalde Y, Franzen A, Suh M, Proctor DM, Harris MA. 2020. Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice. Regul Toxicol Pharmacol 116:104729; 10.1016/j.yrtph.2020.104729. Open access.

Lafranconi M, Budinsky R, Corey L, Haws L, Klapacz J, Chappell G, Golden R. Exposure to 1,4-dioxane above the metabolic saturation threshold induces a mitogenic key element in the mouse liver cancer mode of action. Abstract #1505 for Society of Toxicology virtual annual meeting, 2020.

East A, Price P, Dawson D, Glen G, Dionisio K, Isaacs K, Hubal EC, Vallero D. The Residential Population Generator (RPGen): Parameterization of residential, demographic, and physiological data to model intraindividual exposure, dose, and risk (presentation). Poster presented at Society of Environmental Toxicology and Chemistry North America 41st Annual Meeting, virtual conference, 2020, DOI: 10.23645/epacomptox.13476864, open access online.

Elbeddini A, Hooda N, Gazarin M, Webster P, McMillan J. 2020. Irinotecan-associated dysarthria in patients with pancreatic cancer: A single site experience. Am J Case Rep, doi: 10.12659/AJCR.924058.

Chesney A, Welsh B, Kimzey A, Lansita J. The process and challenges of deriving exposure-based limits for toxicological risk assessment for components and impurities present in cell therapy products with case studies. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

Bell S, Abedini J, Ceger P, Chang X, Cook B, Karmaus AL, Lea I, Mansouri K, Phillips J, McAfee E, Rai R, Rooney J, Sprankle C, Tandon A, Allen D, Casey W, Kleinstreuer N. 2020. An integrated chemical environment with tools for chemical safety testing. Toxicol in Vitro 67:104916.

Zorn KM, Foil DH, Russo DP, Clark AM, Hillwalker W, Feifarek D, Jones F, Klaren W, Brinkman A, Ekins S. Generation of machine-learning models to anticipate endocrine disruption. Society of Toxicology Annual Meeting, virtual, 2020.