2016 (70 POSTS)
Sisler JD, Pirela SV, Shaffer J, Mihalchik AL , Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, et al. 2016. Toxicological assessment of CoO and La2 O3 metal oxide nanoparticles in human small airway epithelial cells. Toxicol Sci 150(2):418-428; doi: 10.1093/toxsci/kfw005 .
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Topics: nanomaterials
2015 (48 POSTS)
Sahmel J, Avens HJ, Scott PK, Unice K, Burns A , Barlow CA, Madl AK, Henshaw J, Paustenbach DJ. 2015. Measured removal rates of chrysotile asbestos fibers from air and comparison with theoretical estimates based on gravitational settling and dilution ventilation. Inhal Toxicol 27(14):787-801; doi: 10.3109/08958378.2015.1110216 . PMID: 26671197.
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Topics: asbestos
James RC, Britt JK , Halmes NC, Guzelian PS. 2015. Evidence-based causation in toxicology: A 10-year retrospective. Hum Exp Toxicol 34(12):1245–1252; doi: 10.1177/0960327115601767 . PMID: 26614812.
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Topics: evidence-based reviews
Wirbisky SE , Freeman JL. 2015. Atrazine exposure and reproductive dysfunction through the hypothalamus-pituitary-gonadal (HPG) axis. Toxics 3(4):414–450; doi: 10.3390/toxics3040414 . PMID: 28713818.
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Topics: atrazine , reproductive toxicology
Madl AK, Kovochich M, Liong M, Finley BL , Paustenbach DJ, Oberdorster G. 2015. Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physiochemical properties and dose in animal and in vitro studies as a basis for risk assessment. Nanomed: Nanotech Biol Med 11(5):1285–1298; doi: 10.1016/j.nano.2015.02.006 . PMID: 25735266.
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Topics: chromium , cobalt , Metals , risk assessment
Wheeler MW, Park R, Bailer A, Whittaker C. 2015. Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits. J Occup Environ Hyg 12(sup1):S7-S17; doi: 10.1080/15459624.2015.1076934 . PMCID: PMC4685605.
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Topics: benchmark dose estimation (BMD) , dose-response , modeling , Occupational , Occupational exposure limits (OELs)
Shah F, Leung L, Barton HA, Will Y, Rodrigues AD, Greene N , Aleo MD. 2015. Setting clinical exposure levels of concern for drug-induced liver injury (DILI) using mechanistic in vitro assays. Toxicol Sci 147(2):500-14; doi: 10.1093/toxsci/kfv152 . PMID: 26206150.
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Topics: drug development , safety assessment
Becker RA, Patlewicz G , Simon T, Rowlands JC, Budinsky RA. 2015. The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor. Regul Toxicol Pharmacol 73(1):172-190; doi: 10.1016/j.yrtph.2015.06.015 . PMID: 26145830.
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Topics: Adverse outcome pathways (AOPs) , mode of action
Bottomley AL , Rowles A, Mitchell DJ, Rasmussen AD. 2015. Detection of mild and reversible neurohistopathological changes in the brain of juvenile (preweaned) beagle dogs treated with vigabatrin for up to 91 days. Toxicol Pathol 43(7):1015-24; doi: 10.1177/0192623315591838 . PMID: 26157036.
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Topics: toxicokinetics
Greene N , Pennie W. 2015. Computational toxicology: Friend or foe? Toxicol Res 4(5):1159-1172; doi: 10.1039/c5tx00055f .
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Topics: computational toxicology
Katz AJ, Chia VM, Schoonen WM, Kelsh MA . 2015. Acute lymphoblastic leukemia: An assessment of international incidence, survival, and disease burden. Cancer Causes Control 26(11):1627–1642.
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Topics: Cancer , Epidemiology
Mackay CE, Vivanco SN , Reinhardt TE, McClure S, Vercellone J. 2015. Real-time monitoring and assessment of thermal and toxicological risk associated with fire retardant textiles in a full-size simulation of an engulfment flash fire. Fire Technol 51(5):1167–1193; doi: 10.1007/s10694-015-0456-3 .
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Topics: flame retardants , risk assessment
Wheeler MW , Shao K, Bailer AJ. 2015. Quantile benchmark dose estimation for continuous endpoints. Environmetrics 26(5):363-72; doi: 10.1002/env.2432 .
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Topics: benchmark dose estimation (BMD) , Exposure Assessment , risk analysis , risk assessment
Thompson CM , Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M , Proctor DM , Bichteler A, Haws LC , Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66; doi: 10.1016/j.mrgentox.2015.05.004 . PMID: 26232259.
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Topics: chromium , microscopy
Young RR, Thompson CM , Dinesdurage HR, Elbekai RH, Suh M , Rohr AC, Proctor DM. 2015. A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats. Environ Mol Mutagen 56(7):629-636; doi: 10.1002/em.21951 . PMID: 25969955.
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Topics: mode of action
Gaffney SH, Abelmann A, Pierce JS, Glynn ME, Henshaw JL, McCarthy LA, Lotter JT, Liong M, Finley BL . 2015. Naturally occurring diacetyl and 2,3-pentanedione concentrations associated with roasting and grinding unflavored coffee beans in a commercial setting. Toxicol Rep 2(Aug 14):1171–1181; doi: 10.1016/j.toxrep.2015.08.003 .
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Topics: diacetyl , food additives
Steinbach T, Gad-McDonald S, Kruhlak N, Powley M, Greene N . 2015. (Q)SAR: A tool for the toxicologist. Int J Toxicol 34(4):352-4; doi: 10.1177/1091581815584914 . PMID: 25979517.
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Topics: computational toxicology
Greene N , Dobo KL, Kenyon MO, Cheung J, Munzner J, Sobol Z, Sluggett G, Zelesky T, et al. 2015. A practical application of two in silico systems for identification of potentially mutagenic impurities. Regul Toxicol Pharmacol 72(2):335-49; doi: 10.1016/j.yrtph.2015.05.008 . PMID: 25980641.
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Topics: computational toxicology , genotoxicity
Wirbisky SE , Weber GJ, Sepúlveda MS, Xiao C, Cannon JR, Freeman JL. 2015. Developmental origins of neurotransmitter and transcriptome alterations in adult female zebrafish exposed to atrazine during embryogenesis. Toxicology 333:156–167.
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Topics: atrazine
Klaren WD , Gadupudi GS, Wels B, Simmons DL, Olivier AK, Ludewig G, Robertson LW. 2015. Progression of micronutrient alteration and hepatotoxicity following acute exposure to PCB126. Toxicol 338(Dec):1–7; doi: 10.1016/j.tox.2015.09.004 . PMID: 26410179.
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