Background and Purpose: Numerous cohort and case-control studies have examined the potential relationship between exposure to asbestos and the development of head and neck cancers. In 2012, The International Agency for Research on Cancer (IARC) concluded that there was sufficient evidence of a causal association between exposure to all forms of asbestos (chrysotile, crocidolite, amosite, tremolite, actinolite, and anthophyllite) and the development of laryngeal cancer. It was noted that positive associations were also observed between exposure to all forms of asbestos and cancer of the pharynx. Further, and despite their conclusion that all forms of asbestos were associated with an increased risk of laryngeal cancer, IARC (2012) noted the following: “there is insufficient information in the published literature to discern whether any differences exist among asbestos fibre types in their ability to cause laryngeal cancer.” The primary studies addressing exposure to asbestos and laryngeal cancer risk included workers from industries that involved exposures to chrysotile fibers (e.g., chrysotile miners), amphibole fibers (e.g., crocidolite miners), or both (e.g., insulators or ship builders), yet no study to date has attempted to determine whether any of the observed associations were influenced by fiber type. Thus, the purpose of this analysis was to conduct a metaanalysis of laryngeal cancer risk in workers occupationally exposed to asbestos by fiber type. Methods: Peer-reviewed manuscripts were screened for relevance and included in the analysis if they met pre-defined inclusion criteria. Included studies underwent data extraction and were categorized into one of four mutually exclusive asbestos fiber type exposure categories: chrysotile; amphibole; mixed; unspecified. Meta-risk ratios (meta-RRs) and their corresponding 95% confidence intervals (CIs) were estimated for each fiber type exposure group using a random effects model. Results: Based on the results from 76 primary studies, an overall meta-RR of 1.27 (95% CI: 1.13-1.42) was calculated. A statistically significantly elevated meta-RR of 1.33 (95% CI: 1.17-1.52) was observed for the unspecified fiber type group (n=38). Among chrysotile-exposed study populations (n=12), the meta-RR was below unity (0.99, 95% CI: 0.94-1.03). Meta-RRs for the amphibole (1.32, 95% CI: 0.67-2.59) and mixed exposure (1.22, 95% CI: 0.94-1.58) groups (n=7 and n=19, respectively) were modestly elevated, but not statistically significant. Conclusions: Limitations included lack of adequate information to ascertain predominant fiber type exposures among half (n = 38) of the studies included, which contributed to a small number of studies in some fiber type specific categories. Nonetheless, the results suggest that groups exposed to chrysotile asbestos had no excess risk of laryngeal cancer, whereas amphibole and mixed exposures were associated with a slight elevation in risk. Overall, the results of this meta-analysis indicate that, similar to cancers of the lung and pleura, fiber potency differences should be considered when investigating the potential relationship between asbestos exposure and risk of laryngeal cancer.