2006 (4 POSTS)
Tompkins EM, Farmer PB, Lamb JH, Jukes R, Dingley K , Ubick E, et al. 2006. A novel 14C-postlabeling assay using accelerator mass spectrometry for the detection of O6-methyldeoxy-guanosine adducts. Rapid Commun Mass Spectrom 20(5):883–891; doi: 10.1002/rcm.2370 . PMID: 16470516.
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Topics: spectrometry
Borowsky AD, Dingley KH , Ubick E, Turteltaub KW, Cardiff RD, Devere-White R. 2006. Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model. Neoplasia 8(9):708–715; doi: 10.1593/neo.06373 . PMID: 16984728.
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Topics: neoplasia
Malfatti MA, Dingley KH , Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573 . PMID: 17079477.
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Topics: Cancer , carcinogens
2005 (3 POSTS)
Ebeler SE, Dingley KH , Ubick E, Abel S, Mitchell AE, Burns SA, et al. 2005. Animal models and analytical approaches for understanding the relationships between wine and cancer. Drugs Exp Clin Res 31(1):19–27. PMID: 15921026 .
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Topics: Cancer , Food science
Rickert DE, Dingley K , Ubick E, Dix KJ, Molina L. 2005. Determination of the tissue distribution and excretion by accelerator mass spectrometry of the nonadecapeptide 14C-Moli1901 in beagle dogs after intratracheal instillation. Chem Biol Interact 155(1–2):55–61; doi: 10.1016/j.cbi.2005.04.002 . PMID: 15893299.
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Topics: spectrometry
Brown K, Dingley KH , Turteltaub KW. 2005. Accelerator mass spectrometry for biomedical research. Methods Enzymol 402:423–443; doi: 10.1016/S0076-6879(05)02014-8 . PMID: 16401518.
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Topics: spectrometry
2004 (3 POSTS)
Cupid BC, Lightfoot TJ, Russell D, Gant SJ, Turner PC, Dingley KH , et al. 2004. The formation of AFB(1)-macromolecular adducts in rats and humans at dietary levels of exposure. Food Chem Toxicol 42(4):559–569; doi: 10.1016/j.fct.2003.10.015 . PMID: 15019179.
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Topics: Exposure Assessment , Food science
Chepanoske CL, Brown K, Turteltaub KW, Dingley KH . 2004. Characterization of a peptide adduct formed by N -acetoxy-2-amino-1-methyl-6-phenylimidazo[4,5-b ]pyridine (PhIP), a reactive intermediate of the food carcinogen PhIP. Food Chem Toxicol 42(8):1367–1372; doi: 10.1016/j.fct.2003.11.012 . PMID: 15207388.
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Topics: carcinogens , Food science
Mally A, Zepnik H, Wanek P, Eder E, Dingley K , Ihmels H., et al. 2004. Ochratoxin A: Lack of formation of covalent DNA adducts. Chem Res Toxicol 17(2):234–242; doi: 10.1021/tx034188m . PMID: 14967011.
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Topics: carcinogens , Toxicology
2003 (3 POSTS)
Turesky RJ, Richoz J, Constable A, Curtis KD, Dingley KH , Turteltaub KW. 2003. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats. Chem-Biol Interact 145(3):251–265; doi: 10.1016/S0009-2797(03)00022-X . PMID: 12732453.
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Topics: carcinogens , Food science
Dingley KH , Ubick EA, Chiarappa-Zucca ML, Nowell S, Abel S, Ebeler SE, et al. 2003. Effect of dietary constituents with chemopreventive potential on adduct formation of a low-dose of the heterocyclic amines PhIP and IQ and phase II hepatic enzymes. Nutr Cancer 46(2):212–221; doi: 10.1207/S15327914NC4602_15 . PMID: 14690798.
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Topics: Cancer , Food science
Martin EA, Gaskell M, Al-Azzawi F, Garner RC, Brown K, Boocock DJ, Mattock E, Pring DW, Dingley K , et al. 2003. Tamoxifen DNA damage detected in human endometrium using the ultra sensitive technique of accelerator mass spectrometry. Cancer Res 63(23):8461–8465. PMID: 14679010.
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Topics: Cancer , spectrometry
2002 (2 POSTS)
Love AH, Hunt JR, Roberts ML, Southon JR, Chiarappa-Zucca ML, Dingley KH . 2002. Use of tritium accelerator mass spectrometry for tree ring analysis. Environ Sci Technol 36(13):2848–2852; doi: 10.1021/es015837o . PMID: 12144257.
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Topics: spectrometry
Williams KE, Carver TA, Miranda JJ, Kautiainen A, Vogel JS, Dingley K , et al. 2002. Attomole detection of in vivo protein targets of benzene in mice: Evidence for a highly reactive metabolite. Mol Cell Proteomics 1(11):885–895; doi: 10.1074/mcp.m200067-mcp200 . PMID: 12488464.
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