Publications

Wikoff D, Fitch S, Vincent M, Southall MD, Atillasoy E, Weinstein RD, Ejaz SD, Rhoden JD, Choksi N. Biological plausibility assessment of acetaminophen and occurrence of developmental neurological outcomes in humans. Abstract 4768, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025. (Honored as one of the Risk Assessment Specialty Section’s Top 10 Abstracts).

Rivera BN, Lea IA, Fitch S, Choksi N, Franzen A, Bus J, Rushton EK, Borghoff SJ. Systematic evaluation of the evidence base on ethyl tert-butyl ether and tert-butyl alcohol for carcinogenic potential in humans: Low concern based on animal cancer studies and mechanistic data. Abstract 4697, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Borghoff SJ, Rivera BN, Fitch S, Buerger A, Choksi N, Franzen A, Bus J, Rushton EK, Lea I. Systematic evaluation of the evidence base on methyl tert-butyl ether for carcinogenic potential in humans; Low concern based on animal cancer studies and mechanistic data. Abstract 4702, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA. 2025. Systematic evaluation of the evidence base on methyl tert-butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224. PMID: 40084233.

Doepker C, Rabert C, Heard P, Dubnicka T, Choksi N, Eapen A. 2024. An investigation of the genotoxic potential of a well-characterized yerba mate extract. Toxicol Rep 12(June):477–484; doi: 10.1016/j.toxrep.2024.04.007. PMID: 38708314.

Mihalchik AL, Choksi NY, Roe AL, Wisser M, Whitaker K, Seibert D, Deore M, Pavlick L, Wikoff DS. 2024. Safety evaluation of 8 drug degradants present in over-the-counter cough and cold medications. Regul Toxicol Pharmacol 149(May):105621; doi: 10.1016/j.yrtph.2024.105621. PMID: 38608922.

Rooney J, Abedini J, Bell S, Chang X, Cook B, Ceger P, Choksi N, et al. Building confidence in alternative methods through ICE. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Allen DG, Rooney J, To K, Choksi N, Ceger P, Daniel A, et al. Variability in reference test method data and the impact on NAM evaluations. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Catalano S, Choksi N, Corvaro M, Kolle S, Stinchombe S, Latorre A, et al. Reducing animal use for eye irritation testing of agrochemicals in Brazil. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Rooney JP, Choksi NY, Ceger P, Daniel AB, Truax J, Allen D, Kleinstreuer N 2021. Analysis of variability in in vivo rabbit skin irritation assay results. Regul Toxicol Pharmacol 122(June):104920; doi: 10.1016/j.yrtph.2021.104920.

Clippinger AJ, Raabe HA, Allen DG, Choksi N, van der Zalm A, Kleinstreuer N, Barroso J, Lowit AB. 2021. Human-relevant approaches to assess eye corrosion/irritation potential of agrochemical formulations. Cutan Ocul Toxicol 40(2):145–167; doi: 10.1080/15569527.2021.1910291.

Choksi NY, Daniel AB, Allen DG, Clippinger AJ, Kleinstreuer NC. 2021. Prospective and retrospective evaluation of the eye irritation potential of agrochemical formulations. Research Triangle Park, NC: National Toxicology Program. NICEATM Report 01.

Rooney JP, Choksi N, Ceger P, Daniel AB, Truax J, Allen DG, Kleinstreuer NC. Variability in the rabbit skin irritation assay. Poster presented at Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Kandarova H, Raabe H, Hilberer A, Choksi N, Allen D. Retrospective review on in vitro phototoxicity data generated in 3D skin models to support the development of new OECD test guideline. Poster presented at Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Ceger P, Allen DG, Choksi N, Daniel A, Eckel W, Hamm J, et al. Retrospective evaluation of the acute fish toxicity test for pesticide registration. Poster presented at Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Choksi N. Identifying data on your chemical. Continuing Education Course: Rapid Chemical Assessment Using Open Computational Methods, Presented at Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Choksi N, Clippinger AJ, Gehen S, Corvaro M, Kolle SN, Bentley K, et al. Developing a defined approach for eye irritation testing. Poster presented at Society of Toxicology 59th Annual Meeting, Virtual, March 2020.

Howard AS, Choksi NY. 2020. Evaluation of two in silico programs for predicting mutagenicity and carcinogenicity potential for 4-methylimidazole (4-MeI) and known metabolites. Toxicol Mech Method 30:246–256; doi: 10.1080/15376516.2019.1709237.

Choksi N, Lebrun S, Nguyen M, Daniel A, DeGeorge G, Willoughby J, et al. 2020. Validation of the OptiSafe Eye Irritation Test. Cutan Ocul Toxicol 39(3):180–192; doi: 10.1080/15569527.2020.1787431.

Choksi NY, Truax J, Layton A, Matheson J, Mattie D, Varney T, et al. 2019. United States regulatory requirements for skin and eye irritation testing. Cutan Ocul Toxicol 38(2):141–155; doi: 10.1080/15569527.2018.1540494.