Mease K , Sane RS, Podila L, Taub ME. 2012. Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: A strategy to assess the interaction of a new chemical entity with P-gp, BCRP and MRP2. J Pharm Sci 101(5):1888–1897; doi: 10.1002/jps.23069 . PMID: 22359351.
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Publication: Manuscripts
/ Topics: drug interactions , modeling
Wang A, Halbert RJ, Baerwaldt T, Nordyke RJ . 2012. U.S. payer perspectives on evidence for formulary decision-making. J Oncol Pract 8(3 Suppl):22s-27s; doi: 10.1200/JOP.2011.000526 . PMID: 22942820.
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Publication: Manuscripts
/ Topics: drug development , Health Economics and Outcomes Research (HEOR)
Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D . 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Publication: Abstracts and Presentations
/ Topics: chromium , modeling , pharmacokinetics
Dobo KL, Greene N , Fred C, Glowienke S, Harvey JS, Hasselgren C, Jolly R, Kenyon MO, et al. 2012. In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey. Regul Toxicol Pharmacol 62(3):449-455; doi: 10.1016/j.yrtph.2012.01.007 . PMID: 22321701.
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Publication: Manuscripts
/ Topics: computational toxicology , genotoxicity
Racz L , Muller JG, Goel RK. 2012. Fate of selected estrogens in two laboratory scale sequencing batch reactors fed with different organic carbon sources. Bioresource Technol 110(April):35–41; doi: 10.1016/j.biortech.2012.01.059 . PMID: 22382291.
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Publication: Manuscripts
/ Topics: computational toxicology
Henderson RG , Durando J, Oller A, Merkel DJ, Marone PA, Bates HK. 2012. Acute oral toxicity of nickel compounds. Regul Toxicol Pharmacol 62(3):425-432; doi: 10.1016/j.yrtph.2012.02.002 . PMID: 22333739.
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Publication: Manuscripts
/ Topics: Metals , nickel
Berman DW, Brorby GP , Sheehan PJ, Bogen KT, Holm SE. 2012. More on the dynamics of dust generation: The effects of mixing and sanding chrysotile, calcium carbonate, and other compounds on the characteristics of joint-compound dusts. Ann Occup Hyg 56(7):852-867.
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Publication: Manuscripts
/ Topics: asbestos
Mwanza JC, Lyke DF, Hertzberg RC, Haber L, Kohrman-Vincent M , Li R, et al. 2012. Cholinesterase inhibition and depression of the photic after discharge flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxur. Neurotoxicol 33(3):332–346; 10.1016/j.neuro.2012.02.006 .
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Publication: Manuscripts
/ Topics: Exposure Assessment
Maier A, Kohrman-Vincent M , Hertzberg R, Allen B, Haber LT, Dourson M. 2012. Critical review of dose-response options for F344 rat mammary tumors for acrylamide – Additional insights based on mode of action. Food Chem Toxicol 50(5):1763–1776; doi: 10.1016/j.fct.2012.02.002 .
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Publication: Manuscripts
/ Topics: mode of action
Barlow CA, Sahmel J, Madl AK, Donovan BL, Gaffney SH, Burns AM , Lee RJ, Van Orden D, Paustenbach DJ. Evaluation of chrysotile adherence to clothing exposed to known airborne asbestos concentrations and subsequent to vigorous shaking. International Society of Exposure Science (ISES) 22nd Annual Meeting, Seattle, WA, 2012.
Publication: Abstracts and Presentations
/ Topics: asbestos , Exposure Assessment
Kopec A, Forgacs AL, Kim S, Thompson CM , Zacharewski T. Comparative toxicogenomic analysis of Cr(VI) effects in rat and mouse small intestine. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Publication: Abstracts and Presentations
/ Topics: chromium
Thompson CM , Proctor DM , Harris MA. 2012. Duodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI). Toxicol Sci 126(1):287-288; doi: 10.1093/toxsci/kfr337 .
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Publication: Manuscripts
/ Topics: chromium
Fowler, JC, Bhattacharya S, Urban JD , Vaidehi N, Mailman RB. 2012. Receptor conformations involved in dopamine D2L receptor functional selectivity induced by selected transmembrane 5 serine mutations. Mol Pharmacol 81(6):820-831; doi: 10.1124/mol.111.075457 . PMID: 22416052.
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Publication: Manuscripts
/ Topics: pharmacokinetics
Lynch M, Brown L, Chun A, Reid J, Russel P. Risk communication for the Toxic Release Inventory. Poster presentation to Society for Risk Analysis, 2012.
Publication: Abstracts and Presentations
/ Topics: risk analysis
Wang X, Greene N . 2012. Comparing measures of promiscuity and exploring their relationship to toxicity. Molec Inform 3(2):145-159; doi: 10.1002/minf.201100148 . PMID: 27476959. Awarded Best Paper of 2012 by the editors of Molecular Informatics .
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Publication: Manuscripts
/ Topics: computational toxicology , pharmacology
O’Brien TJ, Hao D, Suh M, Proctor D, Thompson CM, Harris MA, Parsons BL, Meyers MB. 2012. K-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.
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Publication: Abstracts and Presentations
/ Topics: chromium , water
Henderson RG , Cappellini D, Seilkop SK, Bates HK, Oller AR. 2012. Oral bioaccessibility testing and read-across hazard assessment of nickel compounds. Regul Toxicol Pharmacol 63(1):20-28; doi: 10.1016/j.yrtph.2012.02.005 .
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Publication: Manuscripts
/ Topics: Metals , nickel , risk assessment
Perry C , Tachovsky JA, Ke M, Urban J , Haws L . Natural gas exploration and production in the Barnett Shale: Assessment of exposures to volatile organic compounds (VOCs). Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Publication: Abstracts and Presentations
/ Topics: VOCs
Urban J , Budinsky R, Rowlands J. 2012. An evaluation of single nucleotide polymorphisms in the human heat shock protein 90kDa alpha and beta isoforms. Drug Metab Pharmacokinet 27(2):268-278; doi: 10.2133/dmpk.DMPK-11-SC-114 .
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Publication: Manuscripts
/ Topics: pharmacokinetics
Proctor DM, Thompson CM, Suh M, Haws LC , Harris MA. 2012. Mode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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