Background and Purpose: Dioxin-like compounds (DLCs) are persistent, ubiquitous environmental contaminants that are formed during incomplete combustion activities and as byproducts of certain industrial chemistries. These compounds bind tightly to organic particulate matter, and are commonly detected at low levels in soils, sediments, and dust. Over the past several decades, regulatory efforts and technological advancements led to dramatic reductions in environmental releases of DLCs into the environment, and biomonitoring efforts in the U.S. demonstrate that human body burdens have been trending downwards. A comprehensive survey of background soil dioxin data published a decade ago found that background DLC concentrations across the U.S. are highly variable. Characterizing levels of background soil contamination is important for risk characterization and risk management, as regulators do not typically develop soil cleanup goals below background. The World Health Organization’s (WHO’s) Toxic Equivalency Factor (TEF) Expert Panel recently updated the 2005 TEFs for DLCs, which had been adopted for risk assessment by regulators around the globe. Based on this effort, the TEFs for a number of DLC congeners were revised from their 2005 TEF values. In their analysis, the WHO TEF Expert Panel noted that the updated TEFs (2022 TEFs) lead to a reduction in dietary DLC toxic equivalency (TEQ) concentration intake estimates; however, it is unclear what impact the 2022 TEFs will have on estimates of TEQ concentrations in environmental media, which can have quite different DLC congener profiles than dietary sources. Methods: In this pilot study we used the 2022 TEFs to recalculate the 2005 TEF-based DLC TEQ concentration estimates from three well-reported U.S. background soil surveys. The updated TEQ concentration estimates were compared with their 2005 TEQ values, and changes in the DLC congener contributions to TEQ were characterized. The 2005 and 2022 TEQ concentrations were compared with US EPA residential soil screening levels for DLCs (cancer based RSL = 4.8 ppt TEQ, noncancer-based RSL = 51 ppt TEQ) to provide insight into the impact the 2022 TEFs could have for soil dioxin risk assessment. Results: Despite smaller 2022 TEFs for some of the lower chlorinated DLCs (e.g., pentachlorinated dioxin and furan congeners) and certain dioxin-like polychlorinated biphenyls (e.g., PCB126), replacing the 2005 TEFs with the 2022 TEFs increased TEQ concentrations in the soil surveys included in this pilot study. The increase in TEQ concentrations was largely driven by larger 2022 TEFs for the hepta- and octachlorinated dioxin and furan congeners. The results showed a greater impact on the urban survey soils than the rural survey soils. The higher background soil 2022 TEQ concentrations also resulted in an increased frequency of soil sample exceedances of US EPA soil TEQ screening levels relative to the 2005 TEQ concentrations. Conclusions: This pilot study illustrates that the 2022 WHO TEFs may lead to higher DLC TEQ concentration estimates in soils when compared with the 2005 WHO TEFs. For the surveys included in this pilot study, this increase was the result of larger TEFs for the more highly chlorinated dioxins and furans, DLC congener groups that are commonly overrepresented in soils relative to lower chlorinated dioxin and furan congener groups. As regulatory bodies begin to consider adopting the 2022 WHO TEFs, these results underscore the utility of updating the broader U.S. background soil DLC survey database as a reference tool for regulators and stakeholders assessing and managing potential risks at sites where DLCs are chemicals of potential concern in soils.