Publications

Vincent M, Wheeler M, Schaefer H, Rhoden J, Fitch S, Wikoff D. Quantitative bias assessment to facilitate assessment of (un)certainty in observational data evaluating acetaminophen use and liver cancer. Abstract 4279, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Buerger AN, Lea IA, Vincent MJ,…, Choksi NY, Britt J, Fitch S, Rogers S, Schaefer H, Haws L,…, Wikoff D, Borghoff SJ. Systematic evaluation of the carcinogenic potential of di-isononyl phthalate in humans. Abstract 3314, Society of Toxicology 65^th Annual Meeting, San Diego, CA, March 2026.

Schaefer H. An introduction to evidence integration. Abstract 1333, Society of Toxicology 64th Annual Meeting, Orlando, FL, 2025

Schaefer HR, Vincent MJ, Burns CJ, Lange SS. 2025. Increasing the utility of epidemiologic studies as key evidence in chemical risk assessment. Toxicol Sci 203(2):166-170; doi: 10.1093/toxsci/kfae134. PMID: 39657235.

Schaefer H. Cadmium–Initiatives to reduce dietary exposure. Society for Risk Analysis Annual Meeting, Austin, TX, 2024.

Schaefer H. Introduction: Challenges associated with the use of epidemiologic studies in chemical risk assessments. Abstract 1295, Society of Toxicology 63^rd Annual Meeting, Salt Lake City, UT, 2024.

Schaefer H. Capturing unknowns: Increasing utility of epidemiologic studies as key evidence in chemical risk assessment. Abstract 1294, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, 2024.

Flannery BM, Turley AE, Anyangwe N, Mattia A, Whiteside C, Hermansky S, Schaefer HR, Tyler T, Fitzpatrick SC. 2023. Retrospective analysis of dog study data from food and color additive petitions. Regul Toxicol Pharmacol 145(Dec):105523; doi: 10.1016/j.yrtph.2023.105523. PMID: 37956767.

Schaefer H. Continued refinement of systematic review to better facilitate risk assessment needs – Discussion of modifications to evidence synthesis and integration when considering observational data in dose-response assessment. German Federal Institute for Risk Assessment, Virtual, 2023.

Schaefer HR, Flannery BM, Crosby LM, Pouillot R, Farakos SMS, Van Doren JM, Dennis S, Fitzpatrick S, Middleton K. 2023. Reassessment of the cadmium toxicological reference value for use in human health assessments of foods. Regul Toxicol Pharmacol 144(Oct):105487; doi: 10.1016/j.yrtph.2023.105487. PMID: 37640100.

Schaefer H. Evidence-based methods in toxicology: Progress in the past decade and collaborative projections for the future. Abstract 1218, Society of Toxicology 62nd Annual Meeting, Nashville, TN, 2023.

Schaefer HR, Flannery BM, Crosby L, Jones-Dominic OE, Punzalan C, Middleton K. 2022. A systematic review of adverse health effects associated with oral cadmium exposure. Regul Toxicol Pharmacol 134(Oct):105243; doi: 10.1016/j.yrtph.2022.105243. PMID: 35981600.

Pouillot R, Farakos SS, Spungen J, Schaefer HR, Flannery BM, Van Doren JM. 2022. Cadmium physiologically based pharmacokinetic (PBPK) models for forward and reverse dosimetry: Review, evaluation, and adaptation to the U.S. population. Toxicol Lett 367(Aug):67-75; doi: 10.1016/j.toxlet.2022.07.812. PMID: 35901988. Corrigendum: Toxicol Lett 2023 377(March):14-15; doi: 10.1016/j.toxlet.2023.01.011.

Flannery BM, Schaefer HR, Middleton KB. 2022. A scoping review of infant and children health effects associated with cadmium exposure. Regul Toxicol Pharmacol 131(Jun):105155; doi: 10.1016/j.yrtph.2022.105155. PMID: 35257832.

Schaefer HR, Dennis S, Fitzpatrick S. 2020. Cadmium: Mitigation strategies to reduce dietary exposure. J Food Sci 85(2):260-267; doi: 10.1111/1750-3841.14997. PMID: 31957884.

Schaefer H, Fitzpatrick S, Flannery B. Chemical contaminants in children’s food: A review of recent literature. Abstract 2640, Society of Toxicology 58^th Annual Meeting, Baltimore, MD, March 2019.

Anyangwe N, Fitzpatrick S, Flannery B, Mattia A, Schaefer H, Tyler T, Whiteside C. Use of dog studies in US FDA’s safety assessments for food additives and color additives. Abstract 2781, Society of Toxicology 58^th Annual Meeting, Baltimore, MD, March 2019.

Toxicology Division, Texas Commission on Environmental Quality. 2017. White Paper: TCEQ Guidelines for Systematic Review and Evidence Integration. December 20. Prepared for Texas Commission on Environmental Quality (TCEQ). Available from: https://www.tceq.texas.gov/downloads/toxicology/dsd/position-white-papers/srguidelines.pdf.

Schaefer HR, Myers, JL. 2017. Guidelines for performing systematic reviews in the development of toxicity factors. Regul Toxicol Pharmacol 91(Dec):124-141; doi: 10.1016/j.yrtph.2017.10.008. PMID: 29080853.

Schaefer HR, Ethridge S, Myers, JL. 2017. Development Support Document for Ethylene Dibromide. CAS Registry No.: 106-93-4. Final. November 29. Prepared for Texas Commission on Environmental Quality (TCEQ). Available from: https://www.tceq.texas.gov/downloads/toxicology/dsd/final/edb.pdf.