Publications

Dobo KL, Greene N, Fred C, Glowienke S, Harvey JS, Hasselgren C, Jolly R, Kenyon MO, et al. 2012. In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey. Regul Toxicol Pharmacol 62(3):449-455; doi: 10.1016/j.yrtph.2012.01.007. PMID: 22321701.

Wang X, Greene N. 2012. Comparing measures of promiscuity and exploring their relationship to toxicity. Molec Inform 3(2):145-159; doi: 10.1002/minf.201100148. PMID: 27476959. Awarded Best Paper of 2012 by the editors of Molecular Informatics.

Boyer S, Muthas D, Greene N. 2011. Information, informatics and modeling in predictive toxicology. Chapter 5 in: Wilson AG, Rotella D, (eds), New Horizons in Predictive Toxicology: Current Status and Application. RSC Drug Discovery Series, Vol. 12. Royal Society of Chemistry Publishing, pp. 70-100; doi: 10.1039/9781849733045-00070.

Enayetallah AE, Ziemek D, Leininger MT, Randhawa R, Yang J, Manion TB, Mather DE,…, Greene N, et al. 2011. Modeling the mechanism of action of a DGAT1 inhibitor using a causal reasoning platform. PLoS One 6(11):e27009; doi: 10.1371/journal.pone.0027009. PMID: 22073239.

Greene N, Song M. 2011. Predicting in vivo safety characteristics using physicochemical properties and in vitro assays. Fut Med Chem 3(12):1503-1511; doi: 10.4155/fmc.11.89. PMID: 21882943.

Greene N, Aleo MD, Louise-May S, Price DA, Will Y. 2010. Using an in vitro cytotoxicity assay to aid in compound selection for in vivo safety studies. Bioorg Med Chem Lett 20(17):5308-5312; doi: 10.1016/j.bmcl.2010.06.129. PMID: 20655216.

Greene N, Fisk L, Naven RT, Note RR, Patel ML, Pelletier DJ. 2010. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol 23(7):1215-1222; doi: 10.1021/tx1000865. PMID: 20553011.

Naven RT, Louise-May S, Greene N. 2010. The computational prediction of genotoxicity. Exp Opin Drug Metabol Toxicol 6(7):1-11; doi: 10.1517/17425255.2010.495118. PMID: 20528613.