Publication Topic

Chappell G, Welsh B, Harvey S, Harris M, Wikoff D. Validation and application of a text mining tool in the identification and categorization of mechanistic data: A case study in improving problem formulation of carcinogenicity assessments. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Wikoff D, Borghoff S, Rager J, Harvey S, Haws L. 2016. A systematic review of the mechanistic evidence of tetrabromobisphenol TBBPA as a human carcinogen according to the ten key characteristics of carcinogens (TKCC) identified by Smith et al. (2016). PROSPERO 2016:CRD42016046429.

Borghoff SJ. Organization and review of mechanistic data according to “Ten Key Characteristics of Carcinogens” (TKCC) {Smith et al., 2016}. Presented at the 42^nd Annual Summer Meeting of the Toxicology Forum, July, Salt Lake City, UT, 2016.

Panko JM, Benson SM, Kreider ML. Meta-analysis of lung cancer risk related to diesel exposure by occupation and evaluation of exposure response. Abstract #2976. Poster at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

Bhusari S, Malarkey DE, Hong HH, Wang Y, Masinde T, Nolan M, Hooth NJ, Lea IA, Vasconcelos D, Sills RC, Hoenerhoff MJ. 2014. Mutation spectra of Kras and Tp53 in urethral and lung neoplasms in B6C3F1 mice treated with 3,3′,4,4′-tetrachloroazobenzene. Toxicol Pathol 42(3):555–564; doi: 10.1177/0192623313491169.

Thompson CM, Proctor DM, Suh M, Haws LC, Hebert CD, Mann JF, Shertzer HG, Hixon JG,Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90; doi: 10.1093/toxsci/kfr280.

Waters MD, Jackson MA, Lea IA. 2010. Characterizing and predicting carcinogenicity and mode-of-action using conventional and toxicogenomics methods. Mutat Res 705(3):184–200; doi: 10.1016/j.mrrev.2010.04.005.

Proctor DM, Gatto NM, Hong SJ, Allamneni KP. 2007. Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment. Toxicol Sci 98(2):313–326; doi: 10.1093/toxsci/kfm075.

Malfatti MA, Dingley KH, Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573. PMID: 17079477.

Chepanoske CL, Brown K, Turteltaub KW, Dingley KH. 2004. Characterization of a peptide adduct formed by N-acetoxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a reactive intermediate of the food carcinogen PhIP. Food Chem Toxicol 42(8):1367–1372; doi: 10.1016/j.fct.2003.11.012. PMID: 15207388.

Mally A, Zepnik H, Wanek P, Eder E, Dingley K, Ihmels H., et al. 2004. Ochratoxin A: Lack of formation of covalent DNA adducts. Chem Res Toxicol 17(2):234–242; doi: 10.1021/tx034188m. PMID: 14967011.

Turesky RJ, Richoz J, Constable A, Curtis KD, Dingley KH, Turteltaub KW. 2003. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats. Chem-Biol Interact 145(3):251–265; doi: 10.1016/S0009-2797(03)00022-X. PMID: 12732453.

Roberts SM, Jordan KE, Warren DA, Britt JK, James RC. 2002. Evaluation of the carcinogenicity of 1,1-dichloroethylene (vinylidene chloride). Regul Toxicol Pharmacol 35(1):44-55; doi: 10.1006/rtph.2001.1518.

Haws LC, Jackson BA, Turnbull D, Dressler WE. 1994. Two approaches for assessing human cancer risk from disperse blue 1. Regul Toxicol Pharmacol. 19(1):80-96; doi: 10.1006/rtph.1994.1007.

Monticello TM, Morgan KT. 1994. Cell proliferation and formaldehyde-induced respiratory carcinogenesis. Risk Anal 14(3):313-319; doi: 10.1111/j.1539-6924.1994.tb00246.x.

Jackson BA. Haws LC, Wixtrom RJ, Starr TB. Secondary mechanisms in carcinogenesis: Breaking out of the no-threshold paradigm. American College of Toxicology Annual Meeting, Savannah, GA, 1991.

Monticello TM, Renne R, Morgan KT. 1991. Chemically induced cell proliferation in upper respiratory tract carcinogenesis. Prog Clin Biol Res 369:323-225.

Goldsworthy TL, Monticello TM, Morgan KT, Bermudez E, Wilson D, Butterworth BE. 1991. Examination of potential mechanisms of carcinogenicity of 1,4-dioxane in rat nasal epithelial cells and hepatocytes. Arch Toxicol 65(1):1-9; doi: 10.1007/BF01973495.

Morgan KT, Monticello TM. 1989. Airflow, mucociliary clearance, and lesion distribution in the nasal passages of experimental animals. In: Feron VJ, Bosland MC (eds), Nasal Carcinogenesis in Rodents: Relevance to Human Risk. Wageningen, Netherlands: Pudec Publications, pp. 36-41.