Publication Topic

Clewell HJ, Gentry PR, Gearhart JM, Covington TR, Banton MI, Andersen ME. 2001. Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone. Toxicol Sci 63(2):160–172; doi: 10.1093/toxsci/63.2.160. PMID: 11568359.

Lau C, Mole ML, Copeland FM, Rogers JM, Kavlock RJ, Shuey DL, Cameron AM, Ellis DH, et al. 2001. Toward a biologically-based dose-response model for the developmental toxicity of 5-fluorouracil in the rat: Acquisition of experimental data. Toxicol Sci 59(1):37–48; doi: 10.1093/toxsci/59.1.37. PMID: 11134542.

Setzer RW, Lau C, Mole ML, Copeland FM, Rogers JM, Kavlock RJ. 2001. Toward a biologically-based dose-response model for the developmental toxicity of 5-fluorouracil in the rat: A mathematical construct. Toxicol Sci 59(1):49–58; doi: 10.1093/toxsci/59.1.49. PMID: 11134543.

Clewell HJ III, Gentry PR, Allen BC, Covington TR, Gearhart JM. 2000. Development of a physiologically-based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment. Environ Health Perspect 108(Suppl 2):283–305; doi: 10.1289/ehp.00108s2283. PMID: 10807559.

Lau C, Anderson ME, Crawford-Brown DJ, Kavlock RJ, Kimmel CA, Knudsen TB, Muneoka K, Rogers JM, Setzer RW, Smith G, Tyl R. 2000. Evaluation of biologically based dose-response modeling for developmental toxicity: A workshop report. Regul Toxicol Pharmacol 31(2 Pt 1):190–199; 10.1006/rtph.1999.1360. PMID: 10854125.

Gentry R, Clewell H, Covington T, Wilson J. Investigation of the impact of benchmark and PBPK modeling on the derivation of MRLs. Poster presented at Society of Toxicology 39th Annual Meeting, Philadelphia, PA, March 2000.

Rish W, Kirman CR, Hays SM, Gargas ML, Andersen ME, Reitz RH, Guengerich FP, Green T, McConnell EE, Buckpit A, Voytek P, Dugard PH. 1999. Developing a physiologically based pharmacokinetic model to describe methylene chloride kinetics at the subcellular level. Toxicologist 48, Paper No. 671. Presented at Society of Toxicology 38th Annual Meeting, New Orleans, LA, March 1999.

Allen BC, Covington TR, Clewell HJ III. 1996. Investigation of the impact of pharmacokinetic variability and uncertainty on risks predicted with a pharmacokinetic model for chloroform. Toxicology 111(1-3):289–303; doi: 10.1016/0300-483X(96)03383-5. PMID: 8711743.

Saltiel J, Choi J-O, Sears Jr DF, Eaker DW, Mallory FB, Mallory CW. 1994. Effect of spectra shifts on the resolution of trans-1-(2-naphthyl)-2-phenylethene conformer UV spectra based upon principal component analysis with self-modeling. J Phys Chem 98(50):13162-13170; doi: 10.1021/j100101a012.

Choksi NY, Hussain A, Myers AM, Owens CE, Harvey RD, Wyrick SD, Baldessarini RJ, Booth RG. Stimulation of brain cAMP and dopamine synthesis by adenosine A2 and σ3 agonists. Poster presented at Society for Neuroscience Annual Meeting, 1994